Reviewed, UniProtKB/Swiss-Prot A8XKV0 (BCA1_CAEBR)

Names and origin

Protein names

Recommended name:
    Beta carbonic anhydrase 1
    EC=4.2.1.1

Gene names

Name:	bca-1
ORF Names:	CBG14861

Organism

Caenorhabditis briggsae [Complete proteome]

Taxonomic identifier

6238 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	270 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Reversible hydration of carbon dioxide By similarity.
Catalytic activity	H2CO3 = CO2 + H2O.
Cofactor	Binds 1 zinc ion per subunit By similarity. UniProtKB P45148
Sequence similarities	Belongs to the beta-class carbonic anhydrase family.

Ontologies

Keywords
Ligand	Metal-binding Zinc
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbon utilization Inferred from electronic annotation. Source: InterPro
Molecular function	carbonate dehydratase activity Inferred from electronic annotation. Source: EC zinc ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 270	270	Beta carbonic anhydrase 1		PRO_0000374065
Sites
	Metal binding	39	1	Zinc By similarity UniProtKB P45148
	Metal binding	41	1	Zinc By similarity UniProtKB P45148
	Metal binding	105	1	Zinc By similarity UniProtKB P45148
	Metal binding	108	1	Zinc By similarity UniProtKB P45148

Sequences

	Sequence		Length	Mass (Da)
	A8XKV0-1 [UniParc]. Last modified December 16, 2008. Version 2. Checksum: 5D2088C567CEF150	FASTA	270	30,739
	10 20 30 40 50 60 MNRIIRGVIQ YNQKIKAGLV KQFEHVSDHP NPTAVMFTCM DSRMLPTRFT QSAVGDMFVV 70 80 90 100 110 120 RNAGNMIPAA PNYGSYSEVS INTEPAALEL AVKRGKIRHV VVCGHSDCKA MNTLYQLHQC 130 140 150 160 170 180 PTKFDVSSPM DQWLRRNGFE SMKKLNERLH IGPKTMKFES EVAPSQSFEA IIDPMEKWSA 190 200 210 220 230 240 EDKLSQINVL QQIMNISTHE FLKDYLEAGN LHLHGAWFNI YDGEVFLFSK DRKRFVVIDE 250 260 270 KTVPSLSAEL ERRCPLPEDK AGDVVIQNLH

References

[1]

"The genome sequence of Caenorhabditis briggsae: a platform for comparative genomics." Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N., Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P., Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W., Hillier L.W. , Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A., Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E., Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K., Durbin R.M., Waterston R.H. PLoS Biol. 1:166-192(2003) [PubMed: 14624247] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AF16.

Cross-references

Sequence databases
EMBLGenBankDDBJ	CAAC02000521 Genomic DNA. Translation: CAP33274.2.
3D structure databases
ModBase	Search...
Genome annotation databases
GenomeReviews	Gene locus bca-1 in contig CU538969_GR.
Organism-specific databases
WormBase	WBGene00035244. Cbr-bca-1.
Family and domain databases
InterPro	IPR015892. Carbonic_anhydrase_CS. [Graphical view]
PROSITE	PS00704. PROK_CO2_ANHYDRASE_1. False negative. PS00705. PROK_CO2_ANHYDRASE_2. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

BCA1_CAEBR

Accession

Primary (citable) accession number: A8XKV0

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 5, 2009
Last sequence update:	December 16, 2008
Last modified:	October 13, 2009
This is version 15 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Caenorhabditis annotation project