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Protein
Submitted name:

Protein CBR-TWK-39

Gene

twk-39

Organism
Caenorhabditis briggsae
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ion channelUniRule annotationSAAS annotation

Keywords - Biological processi

Ion transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Protein CBR-TWK-39Imported
Gene namesi
Name:twk-39Imported
Synonyms:Cbr-twk-39Imported
ORF Names:CBG13294Imported, CBG_13294Imported
OrganismiCaenorhabditis briggsaeImported
Taxonomic identifieri6238 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000008549 Componenti: Chromosome III

Organism-specific databases

WormBaseiCBG13294a; CBP45333; WBGene00034073; Cbr-twk-39.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei21 – 44HelicalSequence analysisAdd BLAST24
Transmembranei119 – 139HelicalSequence analysisAdd BLAST21
Transmembranei151 – 172HelicalSequence analysisAdd BLAST22
Transmembranei178 – 193HelicalSequence analysisAdd BLAST16
Transmembranei495 – 514HelicalSequence analysisAdd BLAST20
Transmembranei556 – 577HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliA8XHH9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini116 – 175Ion_trans_2InterPro annotationAdd BLAST60
Domaini503 – 579Ion_trans_2InterPro annotationAdd BLAST77

Sequence similaritiesi

Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1418. Eukaryota.
COG1226. LUCA.
HOGENOMiHOG000217931.
InParanoidiA8XHH9.
OMAiSPAREYK.
OrthoDBiEOG091G03S1.

Family and domain databases

InterProiIPR003280. 2pore_dom_K_chnl.
IPR013099. K_chnl_dom.
[Graphical view]
PfamiPF07885. Ion_trans_2. 2 hits.
[Graphical view]
PRINTSiPR01333. 2POREKCHANEL.

Sequencei

Sequence statusi: Complete.

A8XHH9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRDEVRSFCL KVTTFVRTAT IFTITHVGLC FLVALYAVAG AFMFQAVEHP
60 70 80 90 100
YEMGLQGKVR NASMKVVDDI YRFINKKNVI EETAVKNESQ WALKEFEMLL
110 120 130 140 150
VHAMNFEGYD EHDEERPTFQ WTFSGALLYS ITVFTTIGYG HICPKTDTGR
160 170 180 190 200
LLTILYSVLG IPLMLLCLAN IAETLAQVFT YIYFKLCCAY CRWQKNRRRV
210 220 230 240 250
RRAALSFRYH PNAAVNVRRV QSSRSAQRHN TVRRHASLNR SRTRSNDTKS
260 270 280 290 300
VRSFNRYETT NAQLSNQPPR FDTMSLPGRR KISAQSRSPN GTMPRLPNFP
310 320 330 340 350
VQKRSFRGAH LQKSNTAINM EQLYTDDKRS RRGRHAVSES PAREYKGGLL
360 370 380 390 400
VRAQHQPEEG VVELKAYGGS AAAFHDLVTR KQRRDDAVPN VIISRTRDED
410 420 430 440 450
VKSDPEKTEE TSMSLTDDED MQKPPRRNNS ARELREKEMM MMHSMTHKQP
460 470 480 490 500
SMDSSTSRRM RDIDGRSYRS DRSERSDEMS LHSLRRNGHR AHEKMPVSVG
510 520 530 540 550
ICIVFAFISG GAWLFAWWEN WNGFDGAYYC FITLSTIGFG DIVPGQALDE
560 570 580 590 600
GSQEKLVVCA LYLLFGMALI AMCFKLMQDD VVQKARWLGQ KIGILARPFE
610 620 630 640 650
LSREIAKHAI FLFGYSISIR DESSESESDF DEDDMIEEDE EDGSEGRNDQ
660 670 680
VYDKRTISSG SSKQNDEYIH PRKYHHHHRR
Length:680
Mass (Da):78,296
Last modified:December 16, 2008 - v2
Checksum:iF871000199C010B5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE601226 Genomic DNA. Translation: CAP32103.2.

Genome annotation databases

EnsemblMetazoaiCBG13294; CBG13294; CBG13294.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE601226 Genomic DNA. Translation: CAP32103.2.

3D structure databases

ProteinModelPortaliA8XHH9.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiCBG13294; CBG13294; CBG13294.

Organism-specific databases

WormBaseiCBG13294a; CBP45333; WBGene00034073; Cbr-twk-39.

Phylogenomic databases

eggNOGiKOG1418. Eukaryota.
COG1226. LUCA.
HOGENOMiHOG000217931.
InParanoidiA8XHH9.
OMAiSPAREYK.
OrthoDBiEOG091G03S1.

Family and domain databases

InterProiIPR003280. 2pore_dom_K_chnl.
IPR013099. K_chnl_dom.
[Graphical view]
PfamiPF07885. Ion_trans_2. 2 hits.
[Graphical view]
PRINTSiPR01333. 2POREKCHANEL.
ProtoNetiSearch...

Entry informationi

Entry nameiA8XHH9_CAEBR
AccessioniPrimary (citable) accession number: A8XHH9
Entry historyi
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: December 16, 2008
Last modified: November 30, 2016
This is version 63 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.