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A8XFH3

- EIF3E_CAEBR

UniProt

A8XFH3 - EIF3E_CAEBR

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Protein
Eukaryotic translation initiation factor 3 subunit E
Gene
eif-3.E, CBG12457
Organism
Caenorhabditis briggsae
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome By similarity.UniRule annotation

GO - Molecular functioni

  1. translation initiation factor activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. formation of translation preinitiation complex Source: UniProtKB-HAMAP
  2. regulation of translational initiation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Eukaryotic translation initiation factor 3 subunit E
Short name:
eIF3e
Alternative name(s):
Eukaryotic translation initiation factor 3 subunit 6
Gene namesi
Name:eif-3.E
ORF Names:CBG12457
OrganismiCaenorhabditis briggsae
Taxonomic identifieri6238 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000008549: Chromosome I, UP000008549: Unassembled WGS sequence

Organism-specific databases

WormBaseiCBG12457; CBP35181; WBGene00033404; Cbr-eif-3.E.

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. eukaryotic 43S preinitiation complex Source: UniProtKB-HAMAP
  2. eukaryotic 48S preinitiation complex Source: UniProtKB-HAMAP
  3. eukaryotic translation initiation factor 3 complex Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 311311Eukaryotic translation initiation factor 3 subunit EUniRule annotation
PRO_0000365977Add
BLAST

Interactioni

Subunit structurei

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex By similarity.

Protein-protein interaction databases

STRINGi6238.CBG12457.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini167 – 273107PCI
Add
BLAST

Sequence similaritiesi

Belongs to the eIF-3 subunit E family.
Contains 1 PCI domain.

Phylogenomic databases

eggNOGiNOG324642.
HOGENOMiHOG000036697.
OrthoDBiEOG7QNVKP.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
HAMAPiMF_03004. eIF3e.
InterProiIPR016650. eIF3e.
IPR000717. PCI_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PANTHERiPTHR10317. PTHR10317. 1 hit.
PfamiPF01399. PCI. 1 hit.
[Graphical view]
SMARTiSM00088. PINT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8XFH3-1 [UniParc]FASTAAdd to Basket

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MFTVDMVDTL FKYSKFMYEC GNYTVASVCL YYYRNLVNQA DPNYLNALYG    50
KLASEILLQE WEHARDDLLK LRAYIDANPF DTEWELVTQR AWLMHWALFV 100
YYNYPKGRDE IIEMFLNQQP YLNAIQVLAP HLLRYLAVAV VTSKSRQKNS 150
LKDLVKVIDI ERHSYKDPVT DFLTCLYIKY DFDEAQEMLQ KCEEVLSNDF 200
FLTAVLGDFR ESARLLIFEM FCRIHQCITI EMLARRLNMS QEEAERWIVD 250
LIRTYRIEGA KIDSKLGQVV MGVKSVSIHE QVMENTKRLT LRAQQIALQL 300
EKGRQDKVKA N 311
Length:311
Mass (Da):36,685
Last modified:December 16, 2008 - v2
Checksum:i82AFD4D0196BD7C6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
HE600913 Genomic DNA. Translation: CAP31434.2.

Genome annotation databases

EnsemblMetazoaiCBG12457; CBG12457; CBG12457.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
HE600913 Genomic DNA. Translation: CAP31434.2 .

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 6238.CBG12457.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai CBG12457 ; CBG12457 ; CBG12457 .

Organism-specific databases

WormBasei CBG12457 ; CBP35181 ; WBGene00033404 ; Cbr-eif-3.E.

Phylogenomic databases

eggNOGi NOG324642.
HOGENOMi HOG000036697.
OrthoDBi EOG7QNVKP.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
HAMAPi MF_03004. eIF3e.
InterProi IPR016650. eIF3e.
IPR000717. PCI_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
PANTHERi PTHR10317. PTHR10317. 1 hit.
Pfami PF01399. PCI. 1 hit.
[Graphical view ]
SMARTi SM00088. PINT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AF16.

Entry informationi

Entry nameiEIF3E_CAEBR
AccessioniPrimary (citable) accession number: A8XFH3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: December 16, 2008
Last modified: February 19, 2014
This is version 41 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Translation initiation factors
    List of translation initiation factor entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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