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A8XFH3

- EIF3E_CAEBR

UniProt

A8XFH3 - EIF3E_CAEBR

Protein

Eukaryotic translation initiation factor 3 subunit E

Gene

eif-3.E

Organism
Caenorhabditis briggsae
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 42 (01 Oct 2014)
      Sequence version 2 (16 Dec 2008)
      Previous versions | rss
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    Functioni

    Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.UniRule annotation

    GO - Molecular functioni

    1. translation initiation factor activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. formation of translation preinitiation complex Source: UniProtKB-HAMAP
    2. regulation of translational initiation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Initiation factor

    Keywords - Biological processi

    Protein biosynthesis

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Eukaryotic translation initiation factor 3 subunit EUniRule annotation
    Short name:
    eIF3eUniRule annotation
    Alternative name(s):
    Eukaryotic translation initiation factor 3 subunit 6UniRule annotation
    Gene namesi
    Name:eif-3.EUniRule annotation
    ORF Names:CBG12457
    OrganismiCaenorhabditis briggsae
    Taxonomic identifieri6238 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
    ProteomesiUP000008549: Chromosome I, UP000008549: Unassembled WGS sequence

    Organism-specific databases

    WormBaseiCBG12457; CBP35181; WBGene00033404; Cbr-eif-3.E.

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. eukaryotic 43S preinitiation complex Source: UniProtKB-HAMAP
    2. eukaryotic 48S preinitiation complex Source: UniProtKB-HAMAP
    3. eukaryotic translation initiation factor 3 complex Source: UniProtKB-HAMAP

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 311311Eukaryotic translation initiation factor 3 subunit EPRO_0000365977Add
    BLAST

    Interactioni

    Subunit structurei

    Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.UniRule annotation

    Protein-protein interaction databases

    STRINGi6238.CBG12457.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini167 – 273107PCIUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the eIF-3 subunit E family.UniRule annotation
    Contains 1 PCI domain.UniRule annotation

    Phylogenomic databases

    eggNOGiNOG324642.
    HOGENOMiHOG000036697.
    OrthoDBiEOG7QNVKP.

    Family and domain databases

    Gene3Di1.10.10.10. 1 hit.
    HAMAPiMF_03004. eIF3e.
    InterProiIPR016650. eIF3e.
    IPR000717. PCI_dom.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view]
    PANTHERiPTHR10317. PTHR10317. 1 hit.
    PfamiPF01399. PCI. 1 hit.
    [Graphical view]
    SMARTiSM00088. PINT. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A8XFH3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFTVDMVDTL FKYSKFMYEC GNYTVASVCL YYYRNLVNQA DPNYLNALYG    50
    KLASEILLQE WEHARDDLLK LRAYIDANPF DTEWELVTQR AWLMHWALFV 100
    YYNYPKGRDE IIEMFLNQQP YLNAIQVLAP HLLRYLAVAV VTSKSRQKNS 150
    LKDLVKVIDI ERHSYKDPVT DFLTCLYIKY DFDEAQEMLQ KCEEVLSNDF 200
    FLTAVLGDFR ESARLLIFEM FCRIHQCITI EMLARRLNMS QEEAERWIVD 250
    LIRTYRIEGA KIDSKLGQVV MGVKSVSIHE QVMENTKRLT LRAQQIALQL 300
    EKGRQDKVKA N 311
    Length:311
    Mass (Da):36,685
    Last modified:December 16, 2008 - v2
    Checksum:i82AFD4D0196BD7C6
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HE600913 Genomic DNA. Translation: CAP31434.2.

    Genome annotation databases

    EnsemblMetazoaiCBG12457; CBG12457; CBG12457.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HE600913 Genomic DNA. Translation: CAP31434.2 .

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 6238.CBG12457.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai CBG12457 ; CBG12457 ; CBG12457 .

    Organism-specific databases

    WormBasei CBG12457 ; CBP35181 ; WBGene00033404 ; Cbr-eif-3.E.

    Phylogenomic databases

    eggNOGi NOG324642.
    HOGENOMi HOG000036697.
    OrthoDBi EOG7QNVKP.

    Family and domain databases

    Gene3Di 1.10.10.10. 1 hit.
    HAMAPi MF_03004. eIF3e.
    InterProi IPR016650. eIF3e.
    IPR000717. PCI_dom.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view ]
    PANTHERi PTHR10317. PTHR10317. 1 hit.
    Pfami PF01399. PCI. 1 hit.
    [Graphical view ]
    SMARTi SM00088. PINT. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AF16.

    Entry informationi

    Entry nameiEIF3E_CAEBR
    AccessioniPrimary (citable) accession number: A8XFH3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 3, 2009
    Last sequence update: December 16, 2008
    Last modified: October 1, 2014
    This is version 42 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programCaenorhabditis annotation project

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Translation initiation factors
      List of translation initiation factor entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3