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A8XFH3 (EIF3E_CAEBR) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Eukaryotic translation initiation factor 3 subunit E

Short name=eIF3e
Alternative name(s):
Eukaryotic translation initiation factor 3 subunit 6
Gene names
Name:eif-3.E
ORF Names:CBG12457
OrganismCaenorhabditis briggsae [Reference proteome]
Taxonomic identifier6238 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Protein attributes

Sequence length311 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome By similarity. HAMAP-Rule MF_03004

Subunit structure

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex By similarity.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_03004.

Sequence similarities

Belongs to the eIF-3 subunit E family.

Contains 1 PCI domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 311311Eukaryotic translation initiation factor 3 subunit E HAMAP-Rule MF_03004
PRO_0000365977

Regions

Domain167 – 273107PCI

Sequences

Sequence LengthMass (Da)Tools
A8XFH3 [UniParc].

Last modified December 16, 2008. Version 2.
Checksum: 82AFD4D0196BD7C6

FASTA31136,685
        10         20         30         40         50         60 
MFTVDMVDTL FKYSKFMYEC GNYTVASVCL YYYRNLVNQA DPNYLNALYG KLASEILLQE 

        70         80         90        100        110        120 
WEHARDDLLK LRAYIDANPF DTEWELVTQR AWLMHWALFV YYNYPKGRDE IIEMFLNQQP 

       130        140        150        160        170        180 
YLNAIQVLAP HLLRYLAVAV VTSKSRQKNS LKDLVKVIDI ERHSYKDPVT DFLTCLYIKY 

       190        200        210        220        230        240 
DFDEAQEMLQ KCEEVLSNDF FLTAVLGDFR ESARLLIFEM FCRIHQCITI EMLARRLNMS 

       250        260        270        280        290        300 
QEEAERWIVD LIRTYRIEGA KIDSKLGQVV MGVKSVSIHE QVMENTKRLT LRAQQIALQL 

       310 
EKGRQDKVKA N 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
HE600913 Genomic DNA. Translation: CAP31434.2.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING6238.CBG12457.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaCBG12457; CBG12457; CBG12457.

Organism-specific databases

WormBaseCBG12457; CBP35181; WBGene00033404; Cbr-eif-3.E.

Phylogenomic databases

eggNOGNOG324642.
HOGENOMHOG000036697.
OrthoDBEOG7QNVKP.

Family and domain databases

Gene3D1.10.10.10. 1 hit.
HAMAPMF_03004. eIF3e.
InterProIPR016650. eIF3e.
IPR000717. PCI_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PANTHERPTHR10317. PTHR10317. 1 hit.
PfamPF01399. PCI. 1 hit.
[Graphical view]
SMARTSM00088. PINT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameEIF3E_CAEBR
AccessionPrimary (citable) accession number: A8XFH3
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: December 16, 2008
Last modified: February 19, 2014
This is version 41 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Relevant documents

SIMILARITY comments

Index of protein domains and families

Translation initiation factors

List of translation initiation factor entries