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Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)]

Gene

gpdh-2

Organism
Caenorhabditis briggsae
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei98NADUniRule annotation1
Binding sitei121SubstrateUniRule annotation1
Binding sitei157NAD; via amide nitrogenUniRule annotation1
Active sitei209Proton acceptorUniRule annotation1
Binding sitei273NADUniRule annotation1
Binding sitei302NADUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 15NADUniRule annotation6

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandNADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)]UniRule annotation (EC:1.1.1.8UniRule annotation)
Gene namesi
Name:gpdh-2Imported
Synonyms:Cbr-gpdh-2Imported
ORF Names:CBG09958Imported, CBG_09958Imported
OrganismiCaenorhabditis briggsaeImported
Taxonomic identifieri6238 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000008549 Componenti: Chromosome III

Organism-specific databases

WormBaseiCBG09958a ; CBP02434 ; WBGene00031452 ; Cbr-gpdh-2

Subcellular locationi

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi6238.CBG09958

Structurei

3D structure databases

ProteinModelPortaliA8XA17
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 176NAD_Gly3P_dh_NInterPro annotationAdd BLAST172
Domaini198 – 343NAD_Gly3P_dh_CInterPro annotationAdd BLAST146

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni273 – 274Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2711 Eukaryota
COG0240 LUCA
HOGENOMiHOG000246855
InParanoidiA8XA17
KOiK00006
OMAiWLCKGFE
OrthoDBiEOG091G0DO6

Family and domain databases

Gene3Di1.10.1040.10, 1 hit
InterProiView protein in InterPro
IPR008927 6-PGluconate_DH-like_C_sf
IPR013328 6PGD_dom2
IPR006168 G3P_DH_NAD-dep
IPR006109 G3P_DH_NAD-dep_C
IPR017751 G3P_DH_NAD-dep_euk
IPR011128 G3P_DH_NAD-dep_N
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF07479 NAD_Gly3P_dh_C, 1 hit
PF01210 NAD_Gly3P_dh_N, 1 hit
PIRSFiPIRSF000114 Glycerol-3-P_dh, 1 hit
PRINTSiPR00077 GPDHDRGNASE
SUPFAMiSSF48179 SSF48179, 1 hit
SSF51735 SSF51735, 1 hit
TIGRFAMsiTIGR03376 glycerol3P_DH, 1 hit
PROSITEiView protein in PROSITE
PS00957 NAD_G3PDH, 1 hit

Sequencei

Sequence statusi: Complete.

A8XA17-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSPKKVTIIG SGNWGSAIAR IVGNTTKSFP DQFDPQVRMY VYEEIVNGEK
60 70 80 90 100
LSEVINTRHE NIKYLPGKIL PENVVAVTDL VKSCEGSNIL IFVVPHQFVK
110 120 130 140 150
GLCEKLVGKI PADTQAISLI KGVSTGGIER GGLKLISEEI KEILKIEVSV
160 170 180 190 200
LMGANLAPEV ANDNFCEATI GCKRKAEDGP LLKKLFHTDN FRINVVEDAH
210 220 230 240 250
TVELCGALKN VVACAAGFTD GLGYGDNTKA AVIRLGLMET TKFVEHYYPG
260 270 280 290 300
SNLETFFESC GIADLITTCY GGRNRKVCEA FVKTGKTLAE VEKELLNGQS
310 320 330 340 350
AQGPLTAEEV YLMMKKTGLD AKFPLFTAVH KICAGEMKPA ELVDCLRNHP

EHM
Length:353
Mass (Da):38,467
Last modified:January 15, 2008 - v1
Checksum:i0EAB0D53A386CF45
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE601459 Genomic DNA Translation: CAP29482.1
RefSeqiXP_002641636.1, XM_002641590.1

Genome annotation databases

EnsemblMetazoaiCBG09958a; CBG09958a; WBGene00031452
GeneIDi8583627
KEGGicbr:CBG09958

Similar proteinsi

Entry informationi

Entry nameiA8XA17_CAEBR
AccessioniPrimary (citable) accession number: A8XA17
Entry historyiIntegrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: May 23, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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