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A8X7W2

- A8X7W2_CAEBR

UniProt

A8X7W2 - A8X7W2_CAEBR

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Protein
Histone deacetylase
Gene
CBG09063, CBG_09063
Organism
Caenorhabditis briggsae
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.UniRule annotation

GO - Molecular functioni

  1. NAD-dependent histone deacetylase activity (H3-K14 specific) Source: UniProtKB-EC
  2. NAD-dependent histone deacetylase activity (H3-K18 specific) Source: UniProtKB-EC
  3. NAD-dependent histone deacetylase activity (H3-K9 specific) Source: UniProtKB-EC
  4. NAD-dependent histone deacetylase activity (H4-K16 specific) Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: UniProtKB-KW
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Chromatin regulatorUniRule annotation, HydrolaseUniRule annotationSAAS annotations

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone deacetylaseUniRule annotation (EC:3.5.1.98UniRule annotation)
Gene namesi
ORF Names:CBG09063Imported, CBG_09063Imported
OrganismiCaenorhabditis briggsaeImported
Taxonomic identifieri6238 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000008549: Chromosome III

Organism-specific databases

WormBaseiCBG09063; CBP08173; WBGene00030730.

Subcellular locationi

Nucleus By similarity UniRule annotation

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi6238.CBG09063.

Structurei

3D structure databases

ProteinModelPortaliA8X7W2.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0123.
HOGENOMiHOG000225180.
KOiK06067.
OMAiFNNYYEY.
OrthoDBiEOG7DNNTW.

Family and domain databases

Gene3Di3.40.800.20. 1 hit.
InterProiIPR000286. His_deacetylse.
IPR003084. His_deacetylse_1.
IPR023801. His_deacetylse_dom.
[Graphical view]
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiPF00850. Hist_deacetyl. 1 hit.
[Graphical view]
PIRSFiPIRSF037913. His_deacetylse_1. 1 hit.
PRINTSiPR01270. HDASUPER.
PR01271. HISDACETLASE.

Sequencei

Sequence statusi: Complete.

A8X7W2-1 [UniParc]FASTAAdd to Basket

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MVAPAPLRDQ SKRRVCYYYD TNVGNYYYGP GHVMKPHRIR MANELILSYG    50
LYQNLSIYRP RPASFEAMTT FHSDEYITFL RDANIDNLNS FGASKGKFSQ 100
NNDDCPLFDG LYEFCQLSCG GSLAAAIKLN KKKTDIAINW MGGLHHAKKS 150
ESSGFCYTND IVVGILELLK FHKRVLYVDI DIHHGDGVEE AFFDTNRVMT 200
VSFHRFGNFF PGTGDIKDVG IYNGRLYSVN VPLSDGITDE SYERIFVPVM 250
KKVMEMFDPQ AVVLQCGADS LYGDRLGKFN LSLRGHGACA EFFRKYDVPL 300
MMVGGGGYTP RNVARCWAYE TSIAVGIEVP NELPFNNYYE YFGPDYKLHI 350
EPSQVLKNDN PDQKLLELQK EIFENLSQLD KVPSVQMQPM EDDTLPVLEF 400
EDIARDEENP DVRLPMSIMD SCQHNDADFY DDENGGDDHR NEANGLRQAE 450
AENNL 455
Length:455
Mass (Da):51,696
Last modified:January 15, 2008 - v1
Checksum:iF47EEA3536489432
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
HE601284 Genomic DNA. Translation: CAP28723.1.
RefSeqiXP_002641202.1. XM_002641156.1.

Genome annotation databases

EnsemblMetazoaiCBG09063; CBG09063; CBG09063.
GeneIDi8583195.
KEGGicbr:CBG09063.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
HE601284 Genomic DNA. Translation: CAP28723.1 .
RefSeqi XP_002641202.1. XM_002641156.1.

3D structure databases

ProteinModelPortali A8X7W2.
ModBasei Search...

Protein-protein interaction databases

STRINGi 6238.CBG09063.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai CBG09063 ; CBG09063 ; CBG09063 .
GeneIDi 8583195.
KEGGi cbr:CBG09063.

Organism-specific databases

CTDi 8583195.
WormBasei CBG09063 ; CBP08173 ; WBGene00030730 .

Phylogenomic databases

eggNOGi COG0123.
HOGENOMi HOG000225180.
KOi K06067.
OMAi FNNYYEY.
OrthoDBi EOG7DNNTW.

Family and domain databases

Gene3Di 3.40.800.20. 1 hit.
InterProi IPR000286. His_deacetylse.
IPR003084. His_deacetylse_1.
IPR023801. His_deacetylse_dom.
[Graphical view ]
PANTHERi PTHR10625. PTHR10625. 1 hit.
Pfami PF00850. Hist_deacetyl. 1 hit.
[Graphical view ]
PIRSFi PIRSF037913. His_deacetylse_1. 1 hit.
PRINTSi PR01270. HDASUPER.
PR01271. HISDACETLASE.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AF16Imported.

Entry informationi

Entry nameiA8X7W2_CAEBR
AccessioniPrimary (citable) accession number: A8X7W2
Entry historyi
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: May 14, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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