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Protein
Submitted name:

Protein CBR-TWK-33

Gene

twk-33

Organism
Caenorhabditis briggsae
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ion channelUniRule annotationSAAS annotation

Keywords - Biological processi

Ion transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Protein CBR-TWK-33Imported
Gene namesi
Name:twk-33Imported
Synonyms:Cbr-twk-33Imported
ORF Names:CBG05682Imported, CBG_05682Imported
OrganismiCaenorhabditis briggsaeImported
Taxonomic identifieri6238 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000008549 Componenti: Chromosome V

Organism-specific databases

WormBaseiCBG05682; CBP21631; WBGene00028085; Cbr-twk-33.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei219 – 23921HelicalSequence analysisAdd
BLAST
Transmembranei344 – 36421HelicalSequence analysisAdd
BLAST
Transmembranei407 – 42620HelicalSequence analysisAdd
BLAST
Transmembranei438 – 45720HelicalSequence analysisAdd
BLAST
Transmembranei464 – 48421HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi6238.CBG05682.

Structurei

3D structure databases

ProteinModelPortaliA8X0F6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini302 – 37170Ion_trans_2InterPro annotationAdd
BLAST
Domaini412 – 48776Ion_trans_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1418. Eukaryota.
COG1226. LUCA.
HOGENOMiHOG000017600.
InParanoidiA8X0F6.
KOiK05323.
OMAiVESRHEK.
OrthoDBiEOG091G05MP.

Family and domain databases

InterProiIPR003280. 2pore_dom_K_chnl.
IPR013099. K_chnl_dom.
[Graphical view]
PfamiPF07885. Ion_trans_2. 2 hits.
[Graphical view]
PRINTSiPR01333. 2POREKCHANEL.

Sequencei

Sequence statusi: Complete.

A8X0F6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDIGIDGHQI NVPKTLFNSC QCACCCSNVK KIHEERDSLH DEEQNLENPD
60 70 80 90 100
SQERKTAISG GESPKLSPDL QKLEDPLEDS DDERPRARSV SVSNADLEER
110 120 130 140 150
NRLDSVSELD KSQFSTHRYT RHASIDRGNA TIGTKVGNPE DPIEKYYERN
160 170 180 190 200
NYTVTGRDRD FYNKLPSHLQ HRMSTHGDGI SRYSSPGALG QPVIPTLRRF
210 220 230 240 250
DKSMYWFAFH RKQIGFRHIC VVILVLLYTL LGAAMFWSVE SRHEKAKTLR
260 270 280 290 300
HVHHLEELLE KLAENMTESV NDINTTTSHS EMKVYIREAY IELMKLEGQY
310 320 330 340 350
KGSTYYKLED PQNNWKWTFE SAFFFSMNVY TTTGYGSIAP ESTLGQFLVC
360 370 380 390 400
LYGFIFVPVT LVVLRDLGQF FLVHLTKLYA LGIQKFRELN GDKHVDEDEI
410 420 430 440 450
ISLPIKACLL LLAAYLGACT VFIYFYDELS GEEAGSGMSI FLCFYFSFIS
460 470 480 490 500
LSTIGLGDVM PNNATFSPII SIIFFFGMAV TKVVNRNTFI AVENGIFGTL
510 520 530 540 550
TLVENKLDGI VTRRSAAVKP EDKVPSPKVQ RAFSMDADSV AQPEEAANEV
560 570 580 590 600
LNNFTVRSIA TFMKSNADIY GGGFGRVQLR RGDLMNTDNQ MTVNSVSQLR
610
HRAPSQSNNN NNTGGGHNV
Length:619
Mass (Da):69,772
Last modified:January 15, 2008 - v1
Checksum:iCBB811596D505930
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE601419 Genomic DNA. Translation: CAP26116.1.
RefSeqiXP_002638629.1. XM_002638583.1.

Genome annotation databases

EnsemblMetazoaiCBG05682; CBG05682; CBG05682.
GeneIDi8580626.
KEGGicbr:CBG05682.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE601419 Genomic DNA. Translation: CAP26116.1.
RefSeqiXP_002638629.1. XM_002638583.1.

3D structure databases

ProteinModelPortaliA8X0F6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6238.CBG05682.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiCBG05682; CBG05682; CBG05682.
GeneIDi8580626.
KEGGicbr:CBG05682.

Organism-specific databases

CTDi8580626.
WormBaseiCBG05682; CBP21631; WBGene00028085; Cbr-twk-33.

Phylogenomic databases

eggNOGiKOG1418. Eukaryota.
COG1226. LUCA.
HOGENOMiHOG000017600.
InParanoidiA8X0F6.
KOiK05323.
OMAiVESRHEK.
OrthoDBiEOG091G05MP.

Family and domain databases

InterProiIPR003280. 2pore_dom_K_chnl.
IPR013099. K_chnl_dom.
[Graphical view]
PfamiPF07885. Ion_trans_2. 2 hits.
[Graphical view]
PRINTSiPR01333. 2POREKCHANEL.
ProtoNetiSearch...

Entry informationi

Entry nameiA8X0F6_CAEBR
AccessioniPrimary (citable) accession number: A8X0F6
Entry historyi
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: September 7, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.