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Protein
Submitted name:

Protein CBR-TWK-35

Gene

twk-35

Organism
Caenorhabditis briggsae
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ion channelUniRule annotationSAAS annotation

Keywords - Biological processi

Ion transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Protein CBR-TWK-35Imported
Gene namesi
Name:twk-35Imported
Synonyms:Cbr-twk-35Imported
ORF Names:CBG05561Imported, CBG_05561Imported
OrganismiCaenorhabditis briggsaeImported
Taxonomic identifieri6238 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000008549 Componenti: Chromosome V

Organism-specific databases

WormBaseiCBG05561; CBP07127; WBGene00027985; Cbr-twk-35.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei142 – 16221HelicalSequence analysisAdd
BLAST
Transmembranei239 – 26022HelicalSequence analysisAdd
BLAST
Transmembranei267 – 28519HelicalSequence analysisAdd
BLAST
Transmembranei337 – 35721HelicalSequence analysisAdd
BLAST
Transmembranei369 – 38618HelicalSequence analysisAdd
BLAST
Transmembranei392 – 41423HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi6238.CBG05561.

Structurei

3D structure databases

ProteinModelPortaliA8X056.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini232 – 29160Ion_trans_2InterPro annotationAdd
BLAST
Domaini345 – 41874Ion_trans_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1418. Eukaryota.
COG1226. LUCA.
HOGENOMiHOG000017820.
InParanoidiA8X056.
KOiK05323.
OMAiAGTICTT.
OrthoDBiEOG744T8R.

Family and domain databases

InterProiIPR003280. 2pore_dom_K_chnl.
IPR013099. K_chnl_dom.
[Graphical view]
PfamiPF07885. Ion_trans_2. 2 hits.
[Graphical view]
PRINTSiPR01333. 2POREKCHANEL.

Sequencei

Sequence statusi: Complete.

A8X056-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLSHGESRQ SFKQKKAEEK RRRSSSGHGP QAKQSLAVLA QLMLPALIEE
60 70 80 90 100
HTAQQEDVFV PAHYRADGSL ASTVTNRRHV LQRVNLLQRA NCQMRKGAAG
110 120 130 140 150
VWDIAGRAHL AGKRKVEQLQ QKPPLWLVIL NRAYHKYGLK HAVLILVFLV
160 170 180 190 200
YCIAGGLIFW LIEEPFQSEL RDKWHQKIYN NRTERVDFMM KRIFNNSDFL
210 220 230 240 250
IYIKGNTTTR LEQFFKEEFA SYENQLGVKW SQQKMDWDFW NAVLFAGTIC
260 270 280 290 300
TTIGYGHIYP MTDAGRLLTM CFALFGIPLM LLVLQDFGKL LTITMKFPWF
310 320 330 340 350
QTKRLMRRIM RCCTKQPIEE MREIERQERH DLDIFDLPLP VGIGLIVVWI
360 370 380 390 400
FICSFVLSVW DHNWTLLESF YFFFTSLSTV GLGDLVPSSP RLLITMFGFI
410 420 430 440 450
LVGLSLVSMV INLLQAKMKS TYEAGRNDDK ALTHHAHTLP TSLGVMQCYS
460 470 480 490 500
ADEEKKADVS ERSLSRSTQT SLSLPGVRQV VLRSDGVHWV NTDTSSPTKS
510 520 530 540 550
PDEVTNLVEM ETALRVCEQI GDNNNEEYSE GESLICETEV LLELGECLSD

LERCDSI
Length:557
Mass (Da):63,788
Last modified:January 15, 2008 - v1
Checksum:iA43A31F9F47A6572
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE601419 Genomic DNA. Translation: CAP26016.1.
RefSeqiXP_002638529.1. XM_002638483.1.

Genome annotation databases

EnsemblMetazoaiCBG05561; CBG05561; CBG05561.
GeneIDi8580526.
KEGGicbr:CBG05561.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE601419 Genomic DNA. Translation: CAP26016.1.
RefSeqiXP_002638529.1. XM_002638483.1.

3D structure databases

ProteinModelPortaliA8X056.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6238.CBG05561.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiCBG05561; CBG05561; CBG05561.
GeneIDi8580526.
KEGGicbr:CBG05561.

Organism-specific databases

CTDi8580526.
WormBaseiCBG05561; CBP07127; WBGene00027985; Cbr-twk-35.

Phylogenomic databases

eggNOGiKOG1418. Eukaryota.
COG1226. LUCA.
HOGENOMiHOG000017820.
InParanoidiA8X056.
KOiK05323.
OMAiAGTICTT.
OrthoDBiEOG744T8R.

Family and domain databases

InterProiIPR003280. 2pore_dom_K_chnl.
IPR013099. K_chnl_dom.
[Graphical view]
PfamiPF07885. Ion_trans_2. 2 hits.
[Graphical view]
PRINTSiPR01333. 2POREKCHANEL.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AF16Imported.

Entry informationi

Entry nameiA8X056_CAEBR
AccessioniPrimary (citable) accession number: A8X056
Entry historyi
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: May 11, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.