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Protein

Aspartate aminotransferase

Gene

got-2.2

Organism
Caenorhabditis briggsae
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartate aminotransferaseUniRule annotation (EC:2.6.1.1UniRule annotation)
Gene namesi
Name:got-2.2Imported
Synonyms:Cbr-got-2.2Imported
ORF Names:CBG05011Imported, CBG_05011Imported
OrganismiCaenorhabditis briggsaeImported
Taxonomic identifieri6238 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000008549 Componenti: Chromosome X

Organism-specific databases

WormBaseiCBG05011; CBP01290; WBGene00027571; Cbr-got-2.2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiA8WYZ3.

Interactioni

Subunit structurei

Homodimer.UniRule annotation

GO - Molecular functioni

Protein-protein interaction databases

STRINGi6238.CBG05011.

Structurei

3D structure databases

ProteinModelPortaliA8WYZ3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini43 – 409Aminotran_1_2InterPro annotationAdd BLAST367

Phylogenomic databases

eggNOGiKOG1411. Eukaryota.
COG1448. LUCA.
HOGENOMiHOG000185898.
InParanoidiA8WYZ3.
KOiK14455.
OMAiWANHAAV.
OrthoDBiEOG091G06G3.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR000796. Asp_trans.
IPR004838. NHTrfase_class1_PyrdxlP-BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11879. PTHR11879. 1 hit.
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
PRINTSiPR00799. TRANSAMINASE.
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00105. AA_TRANSFER_CLASS_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8WYZ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVSKKLFST AVRGKSWWSH VEMGPPDAIL GVTEAFKADK NPKKINLGVG
60 70 80 90 100
AYRDDQGKPF VLPSVKEAER QVIAANLDKE YAGIVGLPEF TKLSAKLALG
110 120 130 140 150
ENSSVITDKR IFTTQSISGT GALRIGSEFL SKYSKTKVIY QPTPTWGNHV
160 170 180 190 200
PVFKFAGMDV KQYRYYDKST CGFDEAGALA DIAQIPEGSV ILLHACAHNP
210 220 230 240 250
TGVDPSREQW KKISDIVKKR NLFVFFDMAY QGFASGDVDN DAFAVRYFLE
260 270 280 290 300
QGHNIVLAQS FAKNMGLYGE RVGAFSVVCA DADEAARVAS QVKILIRPLY
310 320 330 340 350
SNPPVHGARI ASRILADPAL NKQWLGDVKL MADRIITMRT QLKDLLAKEG
360 370 380 390 400
STRNWEHITN QIGMFCFTGI NPQQVEKLIK EHSVYLTKDG RISVAGISSN
410
NVAYLAHALH QVTK
Length:414
Mass (Da):45,631
Last modified:January 15, 2008 - v1
Checksum:i80E57946703CE7EA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE600917 Genomic DNA. Translation: CAP25602.1.
RefSeqiXP_002644843.1. XM_002644797.1.

Genome annotation databases

EnsemblMetazoaiCBG05011; CBG05011; CBG05011.
GeneIDi8586839.
KEGGicbr:CBG05011.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE600917 Genomic DNA. Translation: CAP25602.1.
RefSeqiXP_002644843.1. XM_002644797.1.

3D structure databases

ProteinModelPortaliA8WYZ3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6238.CBG05011.

Proteomic databases

PRIDEiA8WYZ3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiCBG05011; CBG05011; CBG05011.
GeneIDi8586839.
KEGGicbr:CBG05011.

Organism-specific databases

CTDi8586839.
WormBaseiCBG05011; CBP01290; WBGene00027571; Cbr-got-2.2.

Phylogenomic databases

eggNOGiKOG1411. Eukaryota.
COG1448. LUCA.
HOGENOMiHOG000185898.
InParanoidiA8WYZ3.
KOiK14455.
OMAiWANHAAV.
OrthoDBiEOG091G06G3.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR000796. Asp_trans.
IPR004838. NHTrfase_class1_PyrdxlP-BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11879. PTHR11879. 1 hit.
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
PRINTSiPR00799. TRANSAMINASE.
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00105. AA_TRANSFER_CLASS_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA8WYZ3_CAEBR
AccessioniPrimary (citable) accession number: A8WYZ3
Entry historyi
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: October 5, 2016
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Miscellaneous

In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.UniRule annotation

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.