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A8WY01

- A8WY01_CAEBR

UniProt

A8WY01 - A8WY01_CAEBR

Protein

Histone deacetylase

Gene

hda-1

Organism
Caenorhabditis briggsae
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 1 (15 Jan 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.UniRule annotation

    GO - Molecular functioni

    1. NAD-dependent histone deacetylase activity (H3-K14 specific) Source: UniProtKB-EC
    2. NAD-dependent histone deacetylase activity (H3-K18 specific) Source: UniProtKB-EC
    3. NAD-dependent histone deacetylase activity (H3-K9 specific) Source: UniProtKB-EC
    4. NAD-dependent histone deacetylase activity (H4-K16 specific) Source: UniProtKB-EC

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Chromatin regulatorUniRule annotation, HydrolaseUniRule annotationSAAS annotation

    Keywords - Biological processi

    Transcription, Transcription regulationUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Histone deacetylaseUniRule annotation (EC:3.5.1.98UniRule annotation)
    Gene namesi
    Name:hda-1Imported
    Synonyms:Cbr-hda-1Imported
    ORF Names:CBG04588Imported, CBG_04588Imported
    OrganismiCaenorhabditis briggsaeImported
    Taxonomic identifieri6238 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
    ProteomesiUP000008549: Chromosome V

    Organism-specific databases

    WormBaseiCBG04588; CBP06924; WBGene00027230; Cbr-hda-1.

    Subcellular locationi

    Nucleus UniRule annotation

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    NucleusUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi6238.CBG04588.

    Structurei

    3D structure databases

    ProteinModelPortaliA8WY01.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the histone deacetylase family. HD Type 1 subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0123.
    HOGENOMiHOG000225180.
    KOiK06067.
    OMAiQIQPDNE.
    OrthoDBiEOG7DNNTW.

    Family and domain databases

    Gene3Di3.40.800.20. 1 hit.
    InterProiIPR000286. His_deacetylse.
    IPR003084. His_deacetylse_1.
    IPR023801. His_deacetylse_dom.
    [Graphical view]
    PANTHERiPTHR10625. PTHR10625. 1 hit.
    PfamiPF00850. Hist_deacetyl. 1 hit.
    [Graphical view]
    PIRSFiPIRSF037913. His_deacetylse_1. 1 hit.
    PRINTSiPR01270. HDASUPER.
    PR01271. HISDACETLASE.

    Sequencei

    Sequence statusi: Complete.

    A8WY01-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNSNGPLQEH GKRRVAYYYD SNIGNYYYGQ GHVMKPHRIR MTHHLVLNYG    50
    LYRSMEIFRP FPATFDDMTR FHSEEYMLFL KSANPDNLKS FNKQMLKFNV 100
    GEDCPLFDGL YEFCQLSSGG SLAAATKLNK QKVDIAINWM GGLHHAKKSE 150
    ASGFCYTNDI VLGILELLKY HKRVLYVDID VHHGDGVEEA FYTTDRVMTV 200
    SFHKYGDFFP GTGDLKDIGA GKGKLYSVNV PLRDGITDSS YQSIFKPIMT 250
    KVMERFDPSA VVLQCGADSL NGDRLGPFNL TLKGHGECAR FFRSYNVPLM 300
    MVGGGGYTPR NVARCWTYET SIAVDREVAN ELPYNDYFEY FGPNYRLHIE 350
    QSNANNENNP ELLTKLQADV IANLEKLTFV PSVQMRPIED DALRSMNDSS 400
    ALVDMADPDR RLPAEVTDQM IQDEGDFYDG EREGDDRRNE SDGKRAAQLD 450
    SEGGK 455
    Length:455
    Mass (Da):51,566
    Last modified:January 15, 2008 - v1
    Checksum:i75F1C52EAC9FF2E9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HE601135 Genomic DNA. Translation: CAP25261.1.
    RefSeqiXP_002637802.1. XM_002637756.1.

    Genome annotation databases

    EnsemblMetazoaiCBG04588; CBG04588; CBG04588.
    GeneIDi8579799.
    KEGGicbr:CBG04588.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HE601135 Genomic DNA. Translation: CAP25261.1 .
    RefSeqi XP_002637802.1. XM_002637756.1.

    3D structure databases

    ProteinModelPortali A8WY01.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 6238.CBG04588.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai CBG04588 ; CBG04588 ; CBG04588 .
    GeneIDi 8579799.
    KEGGi cbr:CBG04588.

    Organism-specific databases

    CTDi 8579799.
    WormBasei CBG04588 ; CBP06924 ; WBGene00027230 ; Cbr-hda-1.

    Phylogenomic databases

    eggNOGi COG0123.
    HOGENOMi HOG000225180.
    KOi K06067.
    OMAi QIQPDNE.
    OrthoDBi EOG7DNNTW.

    Family and domain databases

    Gene3Di 3.40.800.20. 1 hit.
    InterProi IPR000286. His_deacetylse.
    IPR003084. His_deacetylse_1.
    IPR023801. His_deacetylse_dom.
    [Graphical view ]
    PANTHERi PTHR10625. PTHR10625. 1 hit.
    Pfami PF00850. Hist_deacetyl. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF037913. His_deacetylse_1. 1 hit.
    PRINTSi PR01270. HDASUPER.
    PR01271. HISDACETLASE.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AF16Imported.

    Entry informationi

    Entry nameiA8WY01_CAEBR
    AccessioniPrimary (citable) accession number: A8WY01
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 15, 2008
    Last sequence update: January 15, 2008
    Last modified: October 1, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3