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A8WY01

- A8WY01_CAEBR

UniProt

A8WY01 - A8WY01_CAEBR

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Protein

Histone deacetylase

Gene

hda-1

Organism
Caenorhabditis briggsae
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.UniRule annotation

GO - Molecular functioni

  1. NAD-dependent histone deacetylase activity (H3-K14 specific) Source: UniProtKB-EC
  2. NAD-dependent histone deacetylase activity (H3-K18 specific) Source: UniProtKB-EC
  3. NAD-dependent histone deacetylase activity (H3-K9 specific) Source: UniProtKB-EC
  4. NAD-dependent histone deacetylase activity (H4-K16 specific) Source: UniProtKB-EC

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: UniProtKB-KW
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Chromatin regulatorUniRule annotation, HydrolaseUniRule annotationSAAS annotation

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone deacetylaseUniRule annotation (EC:3.5.1.98UniRule annotation)
Gene namesi
Name:hda-1Imported
Synonyms:Cbr-hda-1Imported
ORF Names:CBG04588Imported, CBG_04588Imported
OrganismiCaenorhabditis briggsaeImported
Taxonomic identifieri6238 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000008549: Chromosome V

Organism-specific databases

WormBaseiCBG04588; CBP06924; WBGene00027230; Cbr-hda-1.

Subcellular locationi

Nucleus UniRule annotation

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi6238.CBG04588.

Structurei

3D structure databases

ProteinModelPortaliA8WY01.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the histone deacetylase family. HD Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0123.
HOGENOMiHOG000225180.
InParanoidiA8WY01.
KOiK06067.
OMAiQIQPDNE.
OrthoDBiEOG7DNNTW.

Family and domain databases

Gene3Di3.40.800.20. 1 hit.
InterProiIPR000286. His_deacetylse.
IPR003084. His_deacetylse_1.
IPR023801. His_deacetylse_dom.
[Graphical view]
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiPF00850. Hist_deacetyl. 1 hit.
[Graphical view]
PIRSFiPIRSF037913. His_deacetylse_1. 1 hit.
PRINTSiPR01270. HDASUPER.
PR01271. HISDACETLASE.

Sequencei

Sequence statusi: Complete.

A8WY01-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNSNGPLQEH GKRRVAYYYD SNIGNYYYGQ GHVMKPHRIR MTHHLVLNYG
60 70 80 90 100
LYRSMEIFRP FPATFDDMTR FHSEEYMLFL KSANPDNLKS FNKQMLKFNV
110 120 130 140 150
GEDCPLFDGL YEFCQLSSGG SLAAATKLNK QKVDIAINWM GGLHHAKKSE
160 170 180 190 200
ASGFCYTNDI VLGILELLKY HKRVLYVDID VHHGDGVEEA FYTTDRVMTV
210 220 230 240 250
SFHKYGDFFP GTGDLKDIGA GKGKLYSVNV PLRDGITDSS YQSIFKPIMT
260 270 280 290 300
KVMERFDPSA VVLQCGADSL NGDRLGPFNL TLKGHGECAR FFRSYNVPLM
310 320 330 340 350
MVGGGGYTPR NVARCWTYET SIAVDREVAN ELPYNDYFEY FGPNYRLHIE
360 370 380 390 400
QSNANNENNP ELLTKLQADV IANLEKLTFV PSVQMRPIED DALRSMNDSS
410 420 430 440 450
ALVDMADPDR RLPAEVTDQM IQDEGDFYDG EREGDDRRNE SDGKRAAQLD

SEGGK
Length:455
Mass (Da):51,566
Last modified:January 15, 2008 - v1
Checksum:i75F1C52EAC9FF2E9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE601135 Genomic DNA. Translation: CAP25261.1.
RefSeqiXP_002637802.1. XM_002637756.1.

Genome annotation databases

EnsemblMetazoaiCBG04588; CBG04588; CBG04588.
GeneIDi8579799.
KEGGicbr:CBG04588.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE601135 Genomic DNA. Translation: CAP25261.1 .
RefSeqi XP_002637802.1. XM_002637756.1.

3D structure databases

ProteinModelPortali A8WY01.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 6238.CBG04588.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai CBG04588 ; CBG04588 ; CBG04588 .
GeneIDi 8579799.
KEGGi cbr:CBG04588.

Organism-specific databases

CTDi 8579799.
WormBasei CBG04588 ; CBP06924 ; WBGene00027230 ; Cbr-hda-1.

Phylogenomic databases

eggNOGi COG0123.
HOGENOMi HOG000225180.
InParanoidi A8WY01.
KOi K06067.
OMAi QIQPDNE.
OrthoDBi EOG7DNNTW.

Family and domain databases

Gene3Di 3.40.800.20. 1 hit.
InterProi IPR000286. His_deacetylse.
IPR003084. His_deacetylse_1.
IPR023801. His_deacetylse_dom.
[Graphical view ]
PANTHERi PTHR10625. PTHR10625. 1 hit.
Pfami PF00850. Hist_deacetyl. 1 hit.
[Graphical view ]
PIRSFi PIRSF037913. His_deacetylse_1. 1 hit.
PRINTSi PR01270. HDASUPER.
PR01271. HISDACETLASE.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AF16Imported.

Entry informationi

Entry nameiA8WY01_CAEBR
AccessioniPrimary (citable) accession number: A8WY01
Entry historyi
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: October 29, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3