Reviewed, UniProtKB/Swiss-Prot A8WXM1 (OXDD1_CAEBR)

Names and origin

Protein names

Recommended name:
    D-aspartate oxidase 1
      Short name=DASOX 1
    EC=1.4.3.1
Alternative name(s):
    DDO 1

Gene names

Name:

CBG04460

Organism

Caenorhabditis briggsae [Complete proteome]

Taxonomic identifier

6238 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	331 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Selectively catalyzes the oxidative deamination of D-aspartate and its N-methylated derivative, N-methyl D-aspartate By similarity.
Catalytic activity	D-aspartate + H(2)O + O(2) = oxaloacetate + NH(3) + H(2)O(2).
Cofactor	FAD By similarity.
Sequence similarities	Belongs to the DAMOX/DASOX family.
Caution	The conserved active site Tyr residue in position 221 is replaced by a Phe.

Ontologies

Keywords
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	D-amino-acid oxidase activity Inferred from electronic annotation. Source: InterPro D-aspartate oxidase activity Inferred from electronic annotation. Source: EC binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 331	331	D-aspartate oxidase 1		PRO_0000317122
Regions
	Nucleotide binding	5 – 19	15	FAD Potential
Sites
	Active site	302	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	A8WXM1-1 [UniParc]. Last modified January 15, 2008. Version 1. Checksum: 87BE766D5D2E7FBD	FASTA	331	37,518
	10 20 30 40 50 60 MLPKIAVIGE GVIGCTSALQ IAKAIPNSKI TIFHDKPFEN SCSAGPAGLF RIDYEENTEY 70 80 90 100 110 120 GRASFAWFSH LYRTTKGAET GVKLVSGHIQ SDNLESLKQQ QRAYGDIVYN FRFLDDRERL 130 140 150 160 170 180 DIFPSPSKHC IHYTAYASEG NKYVPYLKRL LLEQKVEFQQ KNVENLDTIA DAGYDVIVNC 190 200 210 220 230 240 AGLYGGKLAG DDDQCYPIRG VILEVDAPWH KHFNYRDFTT FTIPKENSVV IGSTKQDNRW 250 260 270 280 290 300 DLEITDEDRN DILSRYIELH PGMREPKILK EWSALRPGRK HVRIESQQRK TTETGKEYTV 310 320 330 VHHYGHGSNG FTLGWGTAIE ATKLVKKALG L

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Caenorhabditis briggsae: a platform for comparative genomics." Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N., Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P., Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W., Hillier L.W. , Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A., Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E., Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K., Durbin R.M., Waterston R.H. PLoS Biol. 1:166-192(2003) [PubMed: 14624247] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AF16.
[2]	The C.briggsae Sequencing Consortium Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases Cited for: SEQUENCE REVISION. Strain: AF16.

Cross-references

Sequence databases
EMBLGenBankDDBJ	CAAC02000460 Genomic DNA. Translation: CAP25156.1.
3D structure databases
ModBase	Search...
Organism-specific databases
WormBase	WBGene00027125. CBG04460.
Family and domain databases
InterPro	IPR006181. D-amino_acid_oxidase_CS. IPR006076. FAD-dep_OxRdtase. IPR016040. NAD(P)-bd. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
Pfam	PF01266. DAO. 1 hit. [Graphical view]
PROSITE	PS00677. DAO. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

OXDD1_CAEBR

Accession

Primary (citable) accession number: A8WXM1

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	January 15, 2008
Last modified:	November 25, 2008
This is version 9 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Caenorhabditis annotation project