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A8WVU7

- CPG1_CAEBR

UniProt

A8WVU7 - CPG1_CAEBR

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Protein

Chondroitin proteoglycan 1

Gene

cpg-1

Organism
Caenorhabditis briggsae
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Required for polar body extrusion during cytokinesis in embryo development. Affects cortical granule size. Shown to have roles in meiotic chromosome segregation, osmotic barrier function and polarization in conjunction with cpg-2. Binds chitin (By similarity).By similarity

GO - Molecular functioni

  1. chitin binding Source: UniProtKB

GO - Biological processi

  1. chitin metabolic process Source: InterPro
  2. embryo development Source: UniProtKB
  3. mitotic cytokinesis Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Developmental protein

Keywords - Biological processi

Cell cycle, Cell division

Keywords - Ligandi

Chitin-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chondroitin proteoglycan 1
Alternative name(s):
Cell junction protein 1
Cytokinesis protein cej-1
Gene namesi
Name:cpg-1
ORF Names:CBG03957
OrganismiCaenorhabditis briggsae
Taxonomic identifieri6238 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000008549: Chromosome I, UP000008549: Unassembled WGS sequence

Organism-specific databases

WormBaseiCBG03957; CBP06611; WBGene00026714; Cbr-cpg-1.

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1818Sequence AnalysisAdd
BLAST
Chaini19 – 686668Chondroitin proteoglycan 1PRO_0000320219Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi46 – 461N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi96 ↔ 109PROSITE-ProRule annotation
Glycosylationi143 – 1431N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi261 ↔ 274PROSITE-ProRule annotation
Glycosylationi285 – 2851N-linked (GlcNAc...)Sequence Analysis
Glycosylationi635 – 6351N-linked (GlcNAc...)Sequence Analysis
Glycosylationi664 – 6641N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Disulfide bond, Glycoprotein, Proteoglycan

Interactioni

Protein-protein interaction databases

STRINGi6238.CBG03957.

Structurei

3D structure databases

ProteinModelPortaliA8WVU7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini63 – 12058Chitin-binding type-2 1PROSITE-ProRule annotationAdd
BLAST
Domaini228 – 28558Chitin-binding type-2 2PROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi316 – 592277Thr-richSequence AnalysisAdd
BLAST

Sequence similaritiesi

Contains 2 chitin-binding type-2 domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiNOG259424.
HOGENOMiHOG000111921.
InParanoidiA8WVU7.
OMAiTTVGYEP.
OrthoDBiEOG7SR4NG.

Family and domain databases

Gene3Di2.170.140.10. 2 hits.
InterProiIPR002557. Chitin-bd_dom.
[Graphical view]
PfamiPF01607. CBM_14. 2 hits.
[Graphical view]
SMARTiSM00494. ChtBD2. 2 hits.
[Graphical view]
SUPFAMiSSF57625. SSF57625. 2 hits.
PROSITEiPS50940. CHIT_BIND_II. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A8WVU7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLPKSVLIVA FLVASSSAQY GVTGMYENLP LESTTVEASG EGSGYNESND
60 70 80 90 100
DGFVTGADAV AIDTDCSTKE DGLYAIGGCS PQFLTCSGGI ARIMDCPANL
110 120 130 140 150
IYDQRIIACE YSYNVPECSG VPQDVSSTQA YYPATEETTP AENVTVPAET
160 170 180 190 200
TVDPYAPVEV ATTAAPSEDV PVETTASPYA PVEVETTTAP AEDVTVPEET
210 220 230 240 250
TVAPYAPVEV YTTAAPANDE PVTRTLLDKT CNGKADGFYS FGQCSDHYIA
260 270 280 290 300
CSNGYTIPMQ CPARLSFDEA RVICDYTMNV PECQNGSGNY EGSAEETTTE
310 320 330 340 350
ASGELPYSNG YGYEETTTAA ADVPSTEGYA PETTAEAWVA PYRLESTTAA
360 370 380 390 400
DVPTTTVGYA PEVIEETTTS EYVEETTTAA DVSTTTTVEY VPEVTETTTA
410 420 430 440 450
PYVEETTTAE YVEETTTAAD VPTTTTVAYA PEVTETTTVP YIEETTTVEE
460 470 480 490 500
ATTAADVPTT TGYVPEVIET TTTPYVEETT TAEYVEETST AADVPTTTTV
510 520 530 540 550
AYAPEVTETT TVPYIEETTT VEEATTAADV PTTTGYVPEV IETTTTPYVE
560 570 580 590 600
ETTTVEETTT TTVAYAPEVV ETTTTPYVEE STTTPYVEET TTALMFHPPQ
610 620 630 640 650
SKATKLPQIH HPASKEHLLS SHAHKTIETV SMDMNLSSSA SRDSSSLQSK
660 670 680
DDAQLLTKLR SATNRTSTKE ATTRTQNMHA HYHRNH
Length:686
Mass (Da):73,321
Last modified:January 15, 2008 - v1
Checksum:i6C43466951D120A8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE600906 Genomic DNA. Translation: CAP24760.1.
RefSeqiXP_002639373.1. XM_002639327.1.

Genome annotation databases

EnsemblMetazoaiCBG03957; CBG03957; CBG03957.
GeneIDi8581366.
KEGGicbr:CBG03957.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE600906 Genomic DNA. Translation: CAP24760.1 .
RefSeqi XP_002639373.1. XM_002639327.1.

3D structure databases

ProteinModelPortali A8WVU7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 6238.CBG03957.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai CBG03957 ; CBG03957 ; CBG03957 .
GeneIDi 8581366.
KEGGi cbr:CBG03957.

Organism-specific databases

CTDi 8581366.
WormBasei CBG03957 ; CBP06611 ; WBGene00026714 ; Cbr-cpg-1.

Phylogenomic databases

eggNOGi NOG259424.
HOGENOMi HOG000111921.
InParanoidi A8WVU7.
OMAi TTVGYEP.
OrthoDBi EOG7SR4NG.

Family and domain databases

Gene3Di 2.170.140.10. 2 hits.
InterProi IPR002557. Chitin-bd_dom.
[Graphical view ]
Pfami PF01607. CBM_14. 2 hits.
[Graphical view ]
SMARTi SM00494. ChtBD2. 2 hits.
[Graphical view ]
SUPFAMi SSF57625. SSF57625. 2 hits.
PROSITEi PS50940. CHIT_BIND_II. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AF16Imported.

Entry informationi

Entry nameiCPG1_CAEBR
AccessioniPrimary (citable) accession number: A8WVU7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: January 15, 2008
Last modified: October 29, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3