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A8WFR0

- LAMP5_DANRE

UniProt

A8WFR0 - LAMP5_DANRE

Protein

Lysosome-associated membrane glycoprotein 5

Gene

lamp5

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 32 (01 Oct 2014)
      Sequence version 1 (15 Jan 2008)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Lysosome-associated membrane glycoprotein 5
    Alternative name(s):
    Lysosome-associated membrane protein 5
    Short name:
    LAMP-5
    Gene namesi
    Name:lamp5
    ORF Names:zgc:165600
    OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
    Taxonomic identifieri7955 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
    ProteomesiUP000000437: Unplaced

    Organism-specific databases

    ZFINiZDB-GENE-080220-19. zgc:165600.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasmic vesicle membrane Source: UniProtKB
    2. dendrite Source: UniProtKB-SubCell
    3. dendrite membrane Source: UniProtKB
    4. early endosome membrane Source: UniProtKB
    5. endoplasmic reticulum-Golgi intermediate compartment membrane Source: UniProtKB
    6. endosome membrane Source: UniProtKB
    7. growth cone membrane Source: UniProtKB
    8. integral component of membrane Source: UniProtKB-KW
    9. plasma membrane Source: UniProtKB
    10. recycling endosome membrane Source: UniProtKB

    Keywords - Cellular componenti

    Cell membrane, Cell projection, Cytoplasmic vesicle, Endosome, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1818Sequence AnalysisAdd
    BLAST
    Chaini19 – 275257Lysosome-associated membrane glycoprotein 5PRO_0000360415Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi24 – 241N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi42 – 421N-linked (GlcNAc...)Sequence Analysis

    Post-translational modificationi

    Glycosylated.By similarity

    Keywords - PTMi

    Glycoprotein

    Structurei

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini19 – 228210ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini250 – 27526CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei229 – 24921HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the LAMP family.Curated

    Keywords - Domaini

    Signal, Transmembrane, Transmembrane helix

    Phylogenomic databases

    HOVERGENiHBG051186.

    Family and domain databases

    InterProiIPR018134. LAMP_CS.
    IPR002000. Lysosome-assoc_membr_glycop.
    [Graphical view]
    PANTHERiPTHR11506. PTHR11506. 1 hit.
    PfamiPF01299. Lamp. 1 hit.
    [Graphical view]
    PROSITEiPS00310. LAMP_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    A8WFR0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEFQLLLLCS VWALGVCAEQ EVENLSGLST NPERDIFVVR ENGTTCLMAE    50
    FAVRFLIPYD VLALNGIDLI TEQTSVAIPR GAQIAGKCGP SESELQISWA 100
    AQAFNFHIYF SKEKRVQGSD GKAPEAEVWK INRVQLVYDT SENTHFINAY 150
    NPGKHTASTH RLSALVTPAG RSYVCAAQQT LTLISSDHQK GVTVSIYDIQ 200
    IQPFDINADF VFSEPYKCVT DQREQLEQTL PLVLGLILGL IIVITISVYH 250
    FHLKLNAAHT QQPTLPRDRS LYKNM 275
    Length:275
    Mass (Da):30,686
    Last modified:January 15, 2008 - v1
    Checksum:i20452432C6B9A8C5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC154416 mRNA. Translation: AAI54417.1.
    RefSeqiNP_001107133.1. NM_001113661.1.
    UniGeneiDr.67298.

    Genome annotation databases

    GeneIDi100006791.
    KEGGidre:100006791.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC154416 mRNA. Translation: AAI54417.1 .
    RefSeqi NP_001107133.1. NM_001113661.1.
    UniGenei Dr.67298.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 100006791.
    KEGGi dre:100006791.

    Organism-specific databases

    ZFINi ZDB-GENE-080220-19. zgc:165600.

    Phylogenomic databases

    HOVERGENi HBG051186.

    Miscellaneous databases

    NextBioi 20787271.

    Family and domain databases

    InterProi IPR018134. LAMP_CS.
    IPR002000. Lysosome-assoc_membr_glycop.
    [Graphical view ]
    PANTHERi PTHR11506. PTHR11506. 1 hit.
    Pfami PF01299. Lamp. 1 hit.
    [Graphical view ]
    PROSITEi PS00310. LAMP_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. NIH - Zebrafish Gene Collection (ZGC) project
      Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Eye.

    Entry informationi

    Entry nameiLAMP5_DANRE
    AccessioniPrimary (citable) accession number: A8WFR0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 20, 2009
    Last sequence update: January 15, 2008
    Last modified: October 1, 2014
    This is version 32 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3