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Protein
Submitted name:

Aquaporin 9

Gene

AQP9

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

TransportUniRule annotation

Enzyme and pathway databases

ReactomeiR-SSC-432030. Transport of glycerol from adipocytes to the liver by Aquaporins.
R-SSC-432047. Passive transport by Aquaporins.

Names & Taxonomyi

Protein namesi
Submitted name:
Aquaporin 9Imported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:AQP9Imported
OrganismiSus scrofa (Pig)
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
Proteomesi
  • UP000008227 Componenti: Chromosome 1

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei30 – 48HelicalSequence analysisAdd BLAST19
Transmembranei54 – 74HelicalSequence analysisAdd BLAST21
Transmembranei104 – 125HelicalSequence analysisAdd BLAST22
Transmembranei158 – 179HelicalSequence analysisAdd BLAST22
Transmembranei191 – 209HelicalSequence analysisAdd BLAST19
Transmembranei243 – 265HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSSSCG00000004597.

Interactioni

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000004954.

Structurei

3D structure databases

ProteinModelPortaliA8WCF7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MIP/aquaporin (TC 1.A.8) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0224. Eukaryota.
COG0580. LUCA.
GeneTreeiENSGT00510000046311.
HOGENOMiHOG000288287.
HOVERGENiHBG106057.
KOiK09877.
OMAiWNETKDA.
OrthoDBiEOG091G0FMS.
TreeFamiTF313173.

Family and domain databases

CDDicd00333. MIP. 1 hit.
Gene3Di1.20.1080.10. 1 hit.
InterProiIPR023271. Aquaporin-like.
IPR015685. Aquaporin_9.
IPR000425. MIP.
IPR022357. MIP_CS.
[Graphical view]
PANTHERiPTHR19139. PTHR19139. 1 hit.
PfamiPF00230. MIP. 1 hit.
[Graphical view]
PRINTSiPR02021. AQUAPORIN9.
PR00783. MINTRINSICP.
SUPFAMiSSF81338. SSF81338. 1 hit.
TIGRFAMsiTIGR00861. MIP. 1 hit.
PROSITEiPS00221. MIP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8WCF7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQPEMEQKKK SLKQRLVLKN SLAKEMLSEF LGTFIMIVLG CGSVAQAVLS
60 70 80 90 100
RGHFGGILTI NIGFPMAVVM AIYATGGVSG GHINPAVSFA LCLFGRMKWS
110 120 130 140 150
KLPFYMGAQF LGAFAGAATL FGIYYDALMS FADGKLLITG ENATAQIFAT
160 170 180 190 200
YPAPYLSLIN AFADQVVATM FLLIIVFAVF DSRNLGVPRG LQPIVIGLLI
210 220 230 240 250
VVIASSLGMN SGCAMNPARD LSPRLFTALA GWGFEVFTAG NNFWWIPVVG
260 270 280 290
PLVGGAIGGL VYVLFIEIHH SYPNPHFEVE QSEDKPEKYE LNVIM
Length:295
Mass (Da):31,888
Last modified:January 15, 2008 - v1
Checksum:iA50461020431AAA0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU302241 Genomic DNA. No translation available.
EU220427 mRNA. Translation: ABW96899.1.
RefSeqiNP_001106154.1. NM_001112684.1.
UniGeneiSsc.58610.
Ssc.61682.

Genome annotation databases

EnsembliENSSSCT00000005078; ENSSSCP00000004954; ENSSSCG00000004597.
GeneIDi100127153.
KEGGissc:100127153.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU302241 Genomic DNA. No translation available.
EU220427 mRNA. Translation: ABW96899.1.
RefSeqiNP_001106154.1. NM_001112684.1.
UniGeneiSsc.58610.
Ssc.61682.

3D structure databases

ProteinModelPortaliA8WCF7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000004954.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSSSCT00000005078; ENSSSCP00000004954; ENSSSCG00000004597.
GeneIDi100127153.
KEGGissc:100127153.

Organism-specific databases

CTDi366.

Phylogenomic databases

eggNOGiKOG0224. Eukaryota.
COG0580. LUCA.
GeneTreeiENSGT00510000046311.
HOGENOMiHOG000288287.
HOVERGENiHBG106057.
KOiK09877.
OMAiWNETKDA.
OrthoDBiEOG091G0FMS.
TreeFamiTF313173.

Enzyme and pathway databases

ReactomeiR-SSC-432030. Transport of glycerol from adipocytes to the liver by Aquaporins.
R-SSC-432047. Passive transport by Aquaporins.

Gene expression databases

BgeeiENSSSCG00000004597.

Family and domain databases

CDDicd00333. MIP. 1 hit.
Gene3Di1.20.1080.10. 1 hit.
InterProiIPR023271. Aquaporin-like.
IPR015685. Aquaporin_9.
IPR000425. MIP.
IPR022357. MIP_CS.
[Graphical view]
PANTHERiPTHR19139. PTHR19139. 1 hit.
PfamiPF00230. MIP. 1 hit.
[Graphical view]
PRINTSiPR02021. AQUAPORIN9.
PR00783. MINTRINSICP.
SUPFAMiSSF81338. SSF81338. 1 hit.
TIGRFAMsiTIGR00861. MIP. 1 hit.
PROSITEiPS00221. MIP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA8WCF7_PIG
AccessioniPrimary (citable) accession number: A8WCF7
Entry historyi
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: November 2, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.