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Protein

Beta-lactamase

Gene

bcl1

Organism
Bacillus clausii
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

A beta-lactam + H2O = a substituted beta-amino acid.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseSAAS annotation
Biological processAntibiotic resistanceSAAS annotation

Enzyme and pathway databases

BRENDAi3.5.2.6. 7525.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-lactamaseSAAS annotation (EC:3.5.2.6SAAS annotation)
Gene namesi
Name:bcl1Imported
OrganismiBacillus clausiiImported
Taxonomic identifieri79880 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL5439.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 36Sequence analysisAdd BLAST36
ChainiPRO_500272608837 – 307Beta-lactamaseSequence analysisAdd BLAST271

Structurei

3D structure databases

ProteinModelPortaliA8RR46.
SMRiA8RR46.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-A beta-lactamase family.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Family and domain databases

InterProiView protein in InterPro
IPR012338. Beta-lactam/transpept-like.
IPR000871. Beta-lactam_class-A.
PRINTSiPR00118. BLACTAMASEA.
SUPFAMiSSF56601. SSF56601. 1 hit.

Sequencei

Sequence statusi: Complete.

A8RR46-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRSFFMLKT KITSSILVGA CLLIGCSNGN EQPVSNEPEP EESVETGEAV
60 70 80 90 100
FKALEEEYAA RLGVFALDTG TGQTVSYRSD ERFTYASAHK PLAVAVLLQQ
110 120 130 140 150
KSIEELEQLI TYSADDLVNY NPITENHVET GMTLRELSDA SIRYSDNTAA
160 170 180 190 200
NFIFDEIGGP EGFKEGLRAI GDTVTEPERI EPELNHVEPG EIQDTSTPEA
210 220 230 240 250
LAKSLQEFAL GEALPADKQE LLIDWLIGNT TGDALIRAGV PEGWEVGDKT
260 270 280 290 300
GAGSYGTRND IAILWPPEKE PIILAVLSSK DEKDAEYDDE LIAKATEEVI

NLLAQTE
Length:307
Mass (Da):33,512
Last modified:January 15, 2008 - v1
Checksum:i9FC232A849F5399E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF540343 Genomic DNA. Translation: ABU39980.1.
RefSeqiWP_035202387.1. NZ_CP012475.1.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiA8RR46_BACCS
AccessioniPrimary (citable) accession number: A8RR46
Entry historyiIntegrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: July 5, 2017
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)