ID   A8QX06_9ACTN            Unreviewed;       702 AA.
AC   A8QX06;
DT   15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT   15-JAN-2008, sequence version 1.
DT   27-MAR-2024, entry version 71.
DE   SubName: Full=TreX {ECO:0000313|EMBL:ABV26724.1};
GN   Name=treX {ECO:0000313|EMBL:ABV26724.1};
OS   Actinoplanes sp. SN223/29.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Actinoplanes.
OX   NCBI_TaxID=442459 {ECO:0000313|EMBL:ABV26724.1};
RN   [1] {ECO:0000313|EMBL:ABV26724.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=SN223/29 {ECO:0000313|EMBL:ABV26724.1};
RA   Lee J.-S., Pape G., Hai T.;
RL   Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ABV26724.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=SN223/29 {ECO:0000313|EMBL:ABV26724.1};
RX   PubMed=18663442; DOI=10.1007/s00253-008-1582-3;
RA   Lee J.S., Hai T., Pape H., Kim T.J., Suh J.W.;
RT   "Three trehalose synthetic pathways in the acarbose-producing Actinoplanes
RT   sp. SN223/29 and evidence for the TreY role in biosynthesis of component
RT   C.";
RL   Appl. Microbiol. Biotechnol. 80:767-778(2008).
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 13 family.
CC       {ECO:0000256|ARBA:ARBA00008061}.
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DR   EMBL; EF364111; ABV26724.1; -; Genomic_DNA.
DR   AlphaFoldDB; A8QX06; -.
DR   CAZy; CBM48; Carbohydrate-Binding Module Family 48.
DR   CAZy; GH13; Glycoside Hydrolase Family 13.
DR   GO; GO:0004133; F:glycogen debranching enzyme activity; IEA:InterPro.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005980; P:glycogen catabolic process; IEA:InterPro.
DR   CDD; cd11326; AmyAc_Glg_debranch; 1.
DR   CDD; cd02856; E_set_GDE_Isoamylase_N; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR044505; GlgX_Isoamylase_N_E_set.
DR   InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR   InterPro; IPR004193; Glyco_hydro_13_N.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR011837; Glycogen_debranch_GlgX.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR014756; Ig_E-set.
DR   NCBIfam; TIGR02100; glgX_debranch; 1.
DR   PANTHER; PTHR43002; GLYCOGEN DEBRANCHING ENZYME; 1.
DR   PANTHER; PTHR43002:SF1; ISOAMYLASE 1, CHLOROPLASTIC; 1.
DR   Pfam; PF00128; Alpha-amylase; 1.
DR   Pfam; PF02922; CBM_48; 1.
DR   SMART; SM00642; Aamy; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF81296; E set domains; 1.
DR   SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE   3: Inferred from homology;
FT   DOMAIN          180..565
FT                   /note="Glycosyl hydrolase family 13 catalytic"
FT                   /evidence="ECO:0000259|SMART:SM00642"
FT   REGION          466..486
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        466..480
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   702 AA;  79824 MW;  3E7E6ED814913B70 CRC64;
     MQVWPGHRYP LGATYDGTGT NFAIFSEVAE AVELCLFDAS GNERKVLLHE QDAFVWHAYL
     PGVEPGQRYG YRVYGPYERT AGRCNPHKLL LDPYARAVDS DIDWHPSLYA YEMGNPDQMS
     DLDSAPYMPK GVVVNPYFDW GNDRRPDIPY HHSVIYETHV KGLTQRHPEI PREMRGTYAA
     IGHPAIIEHL KSLGVTAVEL MPVHQFVHDN RLHDLGLRNY WGYNTLGFFA PYHGYSGTGT
     LGQQTQEFRG MVKALHAAGM EVILDVVYNH TAEGNHLGPT LSLKGIDNRT YYRLVDDQPQ
     FYMDYTGTGN SLNVRSPQSL QLIMDSLRYW VTEMHVDGFR FDLASTLARE FYDVDRLSTF
     FEVVQQDPIV GQVKLIAEPW DVGPGGYQVG NFPPNWTEWN GKYRDTVRDF WRGEPATLAE
     FASRITGSAD LYQDDGRKPF HSINFVTAHD GFTLNDLVAY NDKHNEANGE ENRDGESHNR
     SWNCGIEGPT QDEKVLELRA KQRRNFLATL MLSQGVPMIS HGDELGRTQQ GNNNAYCQDD
     EISWIDWENA DEQLLEFARK LTAFRHRHQV FQRRRFFTGL PVTARGGGDP LPDLEWFTPD
     GRPMAGDDWG NDFGRAVALF VNGEGIRERG QYGQRHVDSS FLLFFNAHDA PIEFATPPAE
     YGEKWEKVIE TAEPSPDRPS VVEAGHKILV PDRSLIVLDR TV
//