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A8QLH9 (A8QLH9_DANRE) Unreviewed, UniProtKB/TrEMBL

Last modified January 22, 2014. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Name:brca2 EMBL ABO27625.1 ZFIN ZDB-GENE-060510-3
OrganismDanio rerio (Zebrafish) (Brachydanio rerio) EMBL ABO27625.1
Taxonomic identifier7955 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Protein attributes

Sequence length2874 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

Sequences

Sequence LengthMass (Da)Tools
A8QLH9 [UniParc].

Last modified January 15, 2008. Version 1.
Checksum: 0D9F99FD015E74BD

FASTA2,874317,416
        10         20         30         40         50         60 
MFENFFHQID RELGPLNPDW FEELNKRASR DEGSAESSKA GENESIKAPE TSALASQLFS 

        70         80         90        100        110        120 
TPRIFKQRHF PQSPDSIPNE KSQNEGANGE LSAFPWTESS PCLFGSAKDS PKFDRSSEKP 

       130        140        150        160        170        180 
RDCFGLLDTP KRSLARSAKQ ISESLGAQIN PDLSWTSSFN TPPSMTPTVI LPTTEDRVAS 

       190        200        210        220        230        240 
ASILKDKESI FVRKLFPSLS KDSENATTLK QDVVTKSESI EADDLGEKTV CSPNESLDIS 

       250        260        270        280        290        300 
SLWKQRVPNA IEDGDVRNTV QNVLDGAEDV LSIFFSNNTS ACRKIKSKER IRKRITNSSE 

       310        320        330        340        350        360 
DVKSVFLTSE PEQKLKADAE TKSPSKNDDS IQWTPLSLSE TILTEGCSST SLVDNNNTVA 

       370        380        390        400        410        420 
PSETNDGAIF KYTSESSQTC PQSVRLESSP EGTQCQKFLL DKSSAFMLNK KPRKFVYQVS 

       430        440        450        460        470        480 
SSDMSTTLTG SKADLPKCLD QTLKEGPSVE ELSVCLNKSS FTNENPIGDQ TQPQAVEQLS 

       490        500        510        520        530        540 
SEHLDHGLDM TQLSKAFAEE FTQEIMAGGL LDMRVQSNQK VQVQPKAEPE PKNKDGNHTD 

       550        560        570        580        590        600 
ISNLADISVN SPNKSTSITT FEISHDSGCP TTFSDLDRTT ASFADIGEYF PTFKTANNKF 

       610        620        630        640        650        660 
ICIPTEAIVK AKASLDEAAG DGLAKTSNQT KPKHFHVTET MCKSVSRSIP APRPPVRQSI 

       670        680        690        700        710        720 
PSNHASGVSV SDASKTDSPK RFKMNLLNCS LPQSDESDCK TGSKTIITVS DAGLQTESLL 

       730        740        750        760        770        780 
KEKLGRSSES SKPIHQKADF ERSAERHAVF DISSTQKPTA VDSSCDDLEE NGTLTASQKA 

       790        800        810        820        830        840 
DVTELCSLLE EANSQYEFTQ YKSTNIGSHN RTTEKEWDPD ILNDIDFDDS FSCDVVKGKH 

       850        860        870        880        890        900 
PSKTNASSVN TSDLISFRSD LKEKQNGTVA LSVTEESALV DGMRSILSKS SDNSHFHTFG 

       910        920        930        940        950        960 
FKTAKGKAIS VSEKSLNKAK HFFEEDYKEA TFTGVINQEH FKTEPSVKTC ISAENNNAQT 

       970        980        990       1000       1010       1020 
KQDVSLSCEE VNAAHNMIHW QEAGNAGTEP NCLRDKTDVV CVDSNIHFGF STARGAKLKV 

      1030       1040       1050       1060       1070       1080 
SEKALEQARM FLNDVDSIGK SQTPKLVPRS SGKHDVSMQS TRLQKTKNLC RGETSIKISQ 

      1090       1100       1110       1120       1130       1140 
PDSGVANQIS NGADITTFNS ENVFQEQKSG NAAKEVCEKI SPSETSMPQP QQGYGFQTAS 

      1150       1160       1170       1180       1190       1200 
GKGVSVLPSA LKKTKAIFKD CDSNIDNLQS TNMEERKTKL DVEIVKQTNA LISNSKSVTF 

      1210       1220       1230       1240       1250       1260 
SDVEEFKTDL INNLDQEAPQ KEVCELKGLQ SEFSNLISSN GNCGFSTASG KKVSVSAEAL 

      1270       1280       1290       1300       1310       1320 
QRAKDVLFES VDGFSCANVY KKTNQVVDIQ LDSSSSGKHK GFCTAGGKKV AFSATGLQKA 

      1330       1340       1350       1360       1370       1380 
KNLFRGCEEE SLTTEQNCKG LSNVLMLACN GVSLIPEPGN SSGGNVGFST AGGRKMDISV 

      1390       1400       1410       1420       1430       1440 
TALQKANNLF KDCEEESLAS RSLAHQGFTT ASGKNVFVSE KALSEVRAVF AGCDETSFSL 

      1450       1460       1470       1480       1490       1500 
ELKKSSENNV GFSTAGGKKV TISDTSLQRT MNLFQDCEEE SLGSRSLKHQ GCKGFTTASG 

      1510       1520       1530       1540       1550       1560 
KNVTVSEKAL SEVRAVFAGC DEASFSHEPK NISGNKIGFS TTVEKMTTAL EMPNNNNNFK 

      1570       1580       1590       1600       1610       1620 
DCEEESLASR NLMHQACKGF TTASGKNVTV SETALNEVKA VFAGCDEATF DLEPKKSLGS 

      1630       1640       1650       1660       1670       1680 
NIGFSTAGGK KVTISSTALQ RAQTLFKDCE EEKEVFESEK APLPTKSFHA RSEDIVDGNL 

      1690       1700       1710       1720       1730       1740 
KFDQTNKKNP RLSTASGKVV SVTKVSLEET STFFREFDNQ NTATDNQLLL RDSSKHYPQH 

      1750       1760       1770       1780       1790       1800 
KDRQTKATLH PKAARNEPAH LDLHSLDFNS CTDTQQIYFE QEAMACTKAL LEDDDLIESA 

      1810       1820       1830       1840       1850       1860 
GLITSEDIDN KRRPSFSDVQ TIESVDQNRK RKRQVDGSSV ADSGQPPLKR QLLSEFDRTL 

      1870       1880       1890       1900       1910       1920 
HAKTSGLTPL KSCPNGTLKD RRVFKYNVHL KPYVTSPVLF PVNQQSNNIE EHCSTESVQK 

      1930       1940       1950       1960       1970       1980 
RCNSDHMGGV FNPPFQKNMN PPTSNSQDAS KVSSGIVLSF NVVNQEENPN SKEMDQIMAI 

      1990       2000       2010       2020       2030       2040 
SKSHCDRGKQ NCNEKNQDSK SKSSSSVQSI PLKIGNFDEK DMIALQESLQ LARDMQDMRL 

      2050       2060       2070       2080       2090       2100 
RKKKRQTIRP VPGSLYLAKT SGVSRKSLRD AVGCTCPSQY TQDELSQHGV HHKVLEITSE 

      2110       2120       2130       2140       2150       2160 
NAESFRFDCS DYFTCEHLME SGALQLADGG WLVPDSKGTV GKEEFFSALC GTPGVDPKLI 

      2170       2180       2190       2200       2210       2220 
SDVWVFNHYR WIIWKRASME RTFPYLIGGL CLTPEQVLLQ LKFRYDVEVD HSQRSALRRI 

      2230       2240       2250       2260       2270       2280 
MERDDTPAKT LVLCVCGIVQ TCQNPEKTMK DDKSPSAKME SCVIWLTDGW YSIKSLLDPP 

      2290       2300       2310       2320       2330       2340 
LSAMLNKGRL KIGDKIVTSG AELVGSQEAC PPLEAPESLM LKISANSTRR ARWDTKLGYY 

      2350       2360       2370       2380       2390       2400 
RDPRPIRLLL SSLYASGGLV SCVNLLVLRS YPTQWMEKKP NSVFIFRNDR AEDREARKHS 

      2410       2420       2430       2440       2450       2460 
NSKHKSLDLL ISKIQTQFEK EMEGKKKKRA QRKTFSRHEI ETLQDGDELY EAMEQDAAVE 

      2470       2480       2490       2500       2510       2520 
TRLSHKQMEA VSKYRCCREE KRQAELQERV QKAVMEAQEA EGGCPNRDVT PVWKLSVIDA 

      2530       2540       2550       2560       2570       2580 
TDMQSNCVYT LNIWRPTREL QGLLREGHRY RAYHLASSEG KKRSGVAHIQ LTATKKTLFQ 

      2590       2600       2610       2620       2630       2640 
DIEVSPEWLH QHFRARECVR FRELQNPHFS SPCGEVDIVG YIVSIEGKQG HCPVLHLVDE 

      2650       2660       2670       2680       2690       2700 
NFDLVTVRTY SSLEQLAVEE LVKPRALVAI CNLQVRVLSG PVPSLYAGEQ ALFSINPKES 

      2710       2720       2730       2740       2750       2760 
YLQEAMAHLK TFAQNYEQFF NLAEEKVSDV VPSGVLGSFQ SPRTPGVQPF PKMNGTVTPQ 

      2770       2780       2790       2800       2810       2820 
QKSSIFSPFT PLNRRTPAST SNSEVKDPKN LKRRRGLDYL SRIPSPPPLI PLKTRAPPCI 

      2830       2840       2850       2860       2870 
NKTFNPPRKS VTPKPPQKEC SPASRPPAGE EKWVHDEELA MIDTQALVGG LMND 

« Hide

References

[1]"Zebrafish brca2/fancD1 Models Human Early Onset Breast Cancer Gene (BRCA2)."
Titus T.A., Wilson C., Starks A.M., Yan Y.L., Frohnmayer J.D., Postlethwait J.H.
Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
EF088196 mRNA. Translation: ABO27625.1.
UniGeneDr.108077.

3D structure databases

ProteinModelPortalA8QLH9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING7955.ENSDARP00000099674.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

ZFINZDB-GENE-060510-3. brca2.

Phylogenomic databases

eggNOGNOG331296.
HOVERGENHBG106730.

Family and domain databases

Gene3D2.40.50.140. 4 hits.
InterProIPR015525. BRCA2.
IPR015187. BRCA2_OB_1.
IPR015188. BRCA2_OB_3.
IPR002093. BRCA2_repeat.
IPR015252. DNA_recomb/repair_BRCA2_hlx.
IPR012340. NA-bd_OB-fold.
IPR015205. Tower.
[Graphical view]
PANTHERPTHR11289. PTHR11289. 1 hit.
PfamPF09169. BRCA-2_helical. 1 hit.
PF09103. BRCA-2_OB1. 1 hit.
PF09104. BRCA-2_OB3. 1 hit.
PF00634. BRCA2. 9 hits.
PF09121. Tower. 1 hit.
[Graphical view]
PIRSFPIRSF002397. BRCA2. 1 hit.
SUPFAMSSF50249. SSF50249. 4 hits.
SSF81872. SSF81872. 1 hit.
PROSITEPS50138. BRCA2_REPEAT. 12 hits.
[Graphical view]
ProtoNetSearch...

Other

NextBio20888361.

Entry information

Entry nameA8QLH9_DANRE
AccessionPrimary (citable) accession number: A8QLH9
Entry history
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: January 22, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)