A8QHU6 (A8QHU6_BRUMA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
ATP-dependent Clp protease, ATP-binding subunit, putative EMBL EDP28174.1

Gene names

ORF Names:

Bm1_57610 EMBL EDP28174.1

Organism

Brugia malayi (Filarial nematode worm) [Complete proteome]

Taxonomic identifier

6279 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Nematoda › Chromadorea › Spirurida › Filarioidea › Onchocercidae › Brugia

Protein attributes

Sequence length	571 AA.
Sequence status	Fragment.
Protein existence	Predicted

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU003299 EMBL EDP28174.1 Nucleotide-binding
Molecular function	Hydrolase Protease EMBL EDP28174.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	protein folding Inferred from electronic annotation. Source: InterPro proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW nucleoside-triphosphatase activity Inferred from electronic annotation. Source: InterPro peptidase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	571	1	EMBL EDP28174.1

Sequences

	Sequence		Length	Mass (Da)
	A8QHU6 [UniParc]. Last modified January 15, 2008. Version 1. Checksum: FE8B1BE5C42A107B	FASTA	571	62,849
	10 20 30 40 50 60 MVCPSSAVVI ARRQCQSFLI VRTVRHITKS GGSSNDSGSG TDDWENNNTS SEHILFRQRI 70 80 90 100 110 120 PLHASVPLTG KHVTTRWNIW RTSSCNSRCD ECGKPLKNIP SSTPSSRYLI CENCRRLFSC 130 140 150 160 170 180 GPPDEDDEKG SILKASEADK KPPYPKEIYG FLNKYIIGQE QAKKTLSVGV YQHYLRLYHN 190 200 210 220 230 240 IENNVSSPAM NNAEGNRPRT GASSSGVLYQ EDYSRTSRAD IRFFSEVTAP QQKHRIASPV 250 260 270 280 290 300 FRPLPENDVP IRLEKSNILL LGPSGVGKTF ITQTLARILD VPIALCDCTS MTQAGYVGED 310 320 330 340 350 360 VESVVQKLVQ NAGGNVERAQ QGIVFLDEID KIAAAHNVQS HAFRDVSGEG VQHALLKLVE 370 380 390 400 410 420 GTLVNVKSSR KSMSTQQDFV QVDTTDILFV ASGAFTALDR IVGKRLDKKT LGLGAKSGMQ 430 440 450 460 470 480 RITDDDKLEA AISKKRDDLL RQADQGDLIS FGIVPELVGR FPVIVPFHSL DKGMLVRVLT 490 500 510 520 530 540 EPTNSLLAQK KLEFAMDGAD LSFSSDALDE IAALALERKT GARALRSIVE KVLLEAKFTV 550 560 570 PGSDIESVHI NRECVQGKAD YVYTRRAQQA T

References

[1]

"Draft genome of the filarial nematode parasite Brugia malayi." Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E., Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T., Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L. , Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M., Pop M., White O., Barton G.J., Carlow C.K.S., Crawford M.J., Daub J., Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F., Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.-W., Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M.A., McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J., Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E., Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G., Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B., Blaxter M.L., Scott A.L. Science 317:1756-1760(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	DS239991 Genomic DNA. Translation: EDP28174.1.
RefSeq	XP_001902980.1. XM_001902945.1.
3D structure databases
ProteinModelPortal	A8QHU6.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6106402.
KEGG	bmy:Bm1_57610.
Organism-specific databases
CTD	6106402.
Phylogenomic databases
InParanoid	A8QHU6.
KO	K03544.
Family and domain databases
InterPro	IPR003593. AAA+_ATPase. IPR013093. ATPase_AAA-2. IPR019489. Clp_ATPase_C. IPR004487. Clp_protease_ATP-bd_su_ClpX. [Graphical view]
PANTHER	PTHR11262:SF4. PTHR11262:SF4. 1 hit.
Pfam	PF07724. AAA_2. 1 hit. PF10431. ClpB_D2-small. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. SM01086. ClpB_D2-small. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A8QHU6_BRUMA

Accession

Primary (citable) accession number: A8QHU6

Entry history

Integrated into UniProtKB/TrEMBL:	January 15, 2008
Last sequence update:	January 15, 2008
Last modified:	October 3, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)