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Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)]

Gene

MGL_2451

Organism
Malassezia globosa (strain ATCC MYA-4612 / CBS 7966) (Dandruff-associated fungus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei123SubstrateUniRule annotation1
Active sitei209Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Ligandi

NADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)]UniRule annotation (EC:1.1.1.8UniRule annotation)
Gene namesi
ORF Names:MGL_2451Imported
OrganismiMalassezia globosa (strain ATCC MYA-4612 / CBS 7966) (Dandruff-associated fungus)Imported
Taxonomic identifieri425265 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaUstilaginomycotinaMalasseziomycetesMalassezialesMalasseziaceaeMalassezia
Proteomesi
  • UP000008837 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:MGL_2451.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi425265.XP_001730655.1.

Structurei

3D structure databases

ProteinModelPortaliA8Q3M8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 175NAD_Gly3P_dh_NInterPro annotationAdd BLAST169
Domaini198 – 342NAD_Gly3P_dh_CInterPro annotationAdd BLAST145

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni274 – 275Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2711. Eukaryota.
COG0240. LUCA.
InParanoidiA8Q3M8.
KOiK00006.
OrthoDBiEOG092C3ZQP.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
SSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.
PROSITEiPS00957. NAD_G3PDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8Q3M8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVAHKQKVAI IGSGNWGSAI AKIAGFNTAR HSDVFEPIVH MYVYEEIVDG
60 70 80 90 100
RKLTSIINED HVNTKYLPHA KLPENVVATP SPEEAARDAT LLVFVLPHQF
110 120 130 140 150
ILNVCKSLKH ALAPDAHAIS MIKGVEVADK NISIFPDVIE KALGIPCAAL
160 170 180 190 200
SGANIANEVA SGLFSETTVG YRPHQRALAE YYVKLFDTPK FRVGMIEDVA
210 220 230 240 250
GVSLCGALKN IIAVGAGFVD GLGWGGNAKA AIMRIGLMEM RRFALEFFKD
260 270 280 290 300
VRPETFTETS AGVADLITTC YGGRNRKCAE AFVKTGKPFN VLEAELLNGQ
310 320 330 340
KLQGTETTRD VYEFLQSRGK IEEYPLFKTI YDISFNGLDP KLLTERL
Length:347
Mass (Da):37,976
Last modified:January 15, 2008 - v1
Checksum:iED90F5ADE4D493B8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAYY01000008 Genomic DNA. Translation: EDP43441.1.
RefSeqiXP_001730655.1. XM_001730603.1.

Genome annotation databases

GeneIDi5854962.
KEGGimgl:MGL_2451.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAYY01000008 Genomic DNA. Translation: EDP43441.1.
RefSeqiXP_001730655.1. XM_001730603.1.

3D structure databases

ProteinModelPortaliA8Q3M8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi425265.XP_001730655.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5854962.
KEGGimgl:MGL_2451.

Organism-specific databases

EuPathDBiFungiDB:MGL_2451.

Phylogenomic databases

eggNOGiKOG2711. Eukaryota.
COG0240. LUCA.
InParanoidiA8Q3M8.
KOiK00006.
OrthoDBiEOG092C3ZQP.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
SSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.
PROSITEiPS00957. NAD_G3PDH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA8Q3M8_MALGO
AccessioniPrimary (citable) accession number: A8Q3M8
Entry historyi
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: October 5, 2016
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.