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Protein

Acetyl-coenzyme A synthetase

Gene

MGL_0349

Organism
Malassezia globosa (strain ATCC MYA-4612 / CBS 7966) (Dandruff-associated fungus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Acetyl-coenzyme A synthetaseUniRule annotation (EC:6.2.1.1UniRule annotation)
Gene namesi
ORF Names:MGL_0349Imported
OrganismiMalassezia globosa (strain ATCC MYA-4612 / CBS 7966) (Dandruff-associated fungus)Imported
Taxonomic identifieri425265 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaUstilaginomycotinaMalasseziomycetesMalassezialesMalasseziaceaeMalassezia
ProteomesiUP000008837 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:MGL_0349.

Structurei

3D structure databases

ProteinModelPortaliA8PT10.
SMRiA8PT10. Positions 29-629.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent AMP-binding enzyme family.UniRule annotation

Phylogenomic databases

InParanoidiA8PT10.
KOiK01895.
OrthoDBiEOG7M3J82.

Family and domain databases

InterProiIPR011904. Ac_CoA_lig.
IPR025110. AMP-bd_C.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
PfamiPF00501. AMP-binding. 1 hit.
PF13193. AMP-binding_C. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02188. Ac_CoA_lig_AcsA. 1 hit.
PROSITEiPS00455. AMP_BINDING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8PT10-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSENEFINIP SRVNGSDKTR PRAHIDETMY NQMHHRSIHE NDQFWAEEAN
60 70 80 90 100
RMISWYVPFK TVQYGDFGRG NIGWFLEGQL NASYNLVDRW AFERPDDIAL
110 120 130 140 150
IWEADEPGSH IYISFSELLD RVCQVAGVLH SLGVRKGDIV IIYMPMIPEA
160 170 180 190 200
VISMLACARI GAVHSVVFAG FSSDSLRDRV QDSRTRVVMT SDEGRRGGRT
210 220 230 240 250
IATKSIVDAA LKECSSVEHV LVAKRTGAVD VPWVDGRDKW LSELAAQQRT
260 270 280 290 300
YFPPVSMNSE DPLFVLYTSG STGKPKGIVH TTAGYLLGAG LSVKHVFDVH
310 320 330 340 350
PGDRFGCMAD IGWITGHTYI VYGPLMNGTA TLIFESTPMY PTPSRYWEVV
360 370 380 390 400
DTHKLTQFYT APTSIRMLRR MGPEHVQNYD LSTLRVLGTV GEPINPEAWH
410 420 430 440 450
WYNEVVGRGH CAIVDTYWMT EGGSHMITSL PGAIKSKPGA ASKPFWGLKP
460 470 480 490 500
VLLDSQTGQE LQGVDTEGVL AMSRPWPSLA RTILNDHSRF LDTYMRPYPG
510 520 530 540 550
YFFTGDSAYR DKDGYIWIRG RVDDVINVSG HRLSTSEIES ALAEHPGVAE
560 570 580 590 600
SAAVGAPDEL TGQTIAVFVA LKPDYVYDSL EDLTKELSIQ VRRAIGPFAT
610 620 630 640 650
PKRILCVRDL PKTRSGKIVR RVLRKIVCNE ADQLGDLSTL SDPSVLDHLL
660
VRADIGATAP CMTSRYCD
Length:668
Mass (Da):74,397
Last modified:January 15, 2008 - v1
Checksum:iFF18630269464BFA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAYY01000001 Genomic DNA. Translation: EDP45360.1.
RefSeqiXP_001732574.1. XM_001732522.1.

Genome annotation databases

GeneIDi5856880.
KEGGimgl:MGL_0349.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAYY01000001 Genomic DNA. Translation: EDP45360.1.
RefSeqiXP_001732574.1. XM_001732522.1.

3D structure databases

ProteinModelPortaliA8PT10.
SMRiA8PT10. Positions 29-629.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5856880.
KEGGimgl:MGL_0349.

Organism-specific databases

EuPathDBiFungiDB:MGL_0349.

Phylogenomic databases

InParanoidiA8PT10.
KOiK01895.
OrthoDBiEOG7M3J82.

Family and domain databases

InterProiIPR011904. Ac_CoA_lig.
IPR025110. AMP-bd_C.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
PfamiPF00501. AMP-binding. 1 hit.
PF13193. AMP-binding_C. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02188. Ac_CoA_lig_AcsA. 1 hit.
PROSITEiPS00455. AMP_BINDING. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC MYA-4612 / CBS 7966Imported.

Entry informationi

Entry nameiA8PT10_MALGO
AccessioniPrimary (citable) accession number: A8PT10
Entry historyi
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: April 29, 2015
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.