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A8PT10

- A8PT10_MALGO

UniProt

A8PT10 - A8PT10_MALGO

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Protein

Acetyl-coenzyme A synthetase

Gene

MGL_0349

Organism
Malassezia globosa (strain ATCC MYA-4612 / CBS 7966) (Dandruff-associated fungus)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.UniRule annotation

GO - Molecular functioni

  1. acetate-CoA ligase activity Source: UniProtKB-EC
  2. AMP binding Source: InterPro
  3. ATP binding Source: UniProtKB-KW

GO - Biological processi

  1. acetyl-CoA biosynthetic process from acetate Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Acetyl-coenzyme A synthetaseUniRule annotation (EC:6.2.1.1UniRule annotation)
Gene namesi
ORF Names:MGL_0349Imported
OrganismiMalassezia globosa (strain ATCC MYA-4612 / CBS 7966) (Dandruff-associated fungus)Imported
Taxonomic identifieri425265 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaUstilaginomycotinaMalasseziomycetesMalassezialesMalasseziaceaeMalassezia
ProteomesiUP000008837: Unassembled WGS sequence

Structurei

3D structure databases

ProteinModelPortaliA8PT10.
SMRiA8PT10. Positions 29-629.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent AMP-binding enzyme family.UniRule annotation

Phylogenomic databases

InParanoidiA8PT10.
KOiK01895.
OrthoDBiEOG7M3J82.

Family and domain databases

InterProiIPR011904. Ac_CoA_lig.
IPR025110. AMP-bd_C.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
PfamiPF00501. AMP-binding. 1 hit.
PF13193. AMP-binding_C. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02188. Ac_CoA_lig_AcsA. 1 hit.
PROSITEiPS00455. AMP_BINDING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8PT10-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSENEFINIP SRVNGSDKTR PRAHIDETMY NQMHHRSIHE NDQFWAEEAN
60 70 80 90 100
RMISWYVPFK TVQYGDFGRG NIGWFLEGQL NASYNLVDRW AFERPDDIAL
110 120 130 140 150
IWEADEPGSH IYISFSELLD RVCQVAGVLH SLGVRKGDIV IIYMPMIPEA
160 170 180 190 200
VISMLACARI GAVHSVVFAG FSSDSLRDRV QDSRTRVVMT SDEGRRGGRT
210 220 230 240 250
IATKSIVDAA LKECSSVEHV LVAKRTGAVD VPWVDGRDKW LSELAAQQRT
260 270 280 290 300
YFPPVSMNSE DPLFVLYTSG STGKPKGIVH TTAGYLLGAG LSVKHVFDVH
310 320 330 340 350
PGDRFGCMAD IGWITGHTYI VYGPLMNGTA TLIFESTPMY PTPSRYWEVV
360 370 380 390 400
DTHKLTQFYT APTSIRMLRR MGPEHVQNYD LSTLRVLGTV GEPINPEAWH
410 420 430 440 450
WYNEVVGRGH CAIVDTYWMT EGGSHMITSL PGAIKSKPGA ASKPFWGLKP
460 470 480 490 500
VLLDSQTGQE LQGVDTEGVL AMSRPWPSLA RTILNDHSRF LDTYMRPYPG
510 520 530 540 550
YFFTGDSAYR DKDGYIWIRG RVDDVINVSG HRLSTSEIES ALAEHPGVAE
560 570 580 590 600
SAAVGAPDEL TGQTIAVFVA LKPDYVYDSL EDLTKELSIQ VRRAIGPFAT
610 620 630 640 650
PKRILCVRDL PKTRSGKIVR RVLRKIVCNE ADQLGDLSTL SDPSVLDHLL
660
VRADIGATAP CMTSRYCD
Length:668
Mass (Da):74,397
Last modified:January 15, 2008 - v1
Checksum:iFF18630269464BFA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAYY01000001 Genomic DNA. Translation: EDP45360.1.
RefSeqiXP_001732574.1. XM_001732522.1.

Genome annotation databases

GeneIDi5856880.
KEGGimgl:MGL_0349.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAYY01000001 Genomic DNA. Translation: EDP45360.1 .
RefSeqi XP_001732574.1. XM_001732522.1.

3D structure databases

ProteinModelPortali A8PT10.
SMRi A8PT10. Positions 29-629.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 5856880.
KEGGi mgl:MGL_0349.

Phylogenomic databases

InParanoidi A8PT10.
KOi K01895.
OrthoDBi EOG7M3J82.

Family and domain databases

InterProi IPR011904. Ac_CoA_lig.
IPR025110. AMP-bd_C.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view ]
Pfami PF00501. AMP-binding. 1 hit.
PF13193. AMP-binding_C. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR02188. Ac_CoA_lig_AcsA. 1 hit.
PROSITEi PS00455. AMP_BINDING. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC MYA-4612 / CBS 7966Imported.

Entry informationi

Entry nameiA8PT10_MALGO
AccessioniPrimary (citable) accession number: A8PT10
Entry historyi
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: October 29, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3