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A8PIP2 (A8PIP2_BRUMA) Unreviewed, UniProtKB/TrEMBL

Last modified October 16, 2013. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
DNA ligase RuleBase RU000617

EC=6.5.1.1 RuleBase RU000617
Gene names
ORF Names:Bm1_26765 EMBL EDP34348.1
OrganismBrugia malayi (Filarial nematode worm) [Complete proteome]
Taxonomic identifier6279 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaNematodaChromadoreaSpiruridaFilarioideaOnchocercidaeBrugia

Protein attributes

Sequence length552 AA.
Sequence statusFragment.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). RuleBase RU000617

Sequence similarities

Belongs to the ATP-dependent DNA ligase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue5521 EMBL EDP34348.1

Sequences

Sequence LengthMass (Da)Tools
A8PIP2 [UniParc].

Last modified January 15, 2008. Version 1.
Checksum: A87111048411F8DF

FASTA55262,357
        10         20         30         40         50         60 
MGKKLFFRIP YLCLAKTFEG IEATSSRLEI VKILASFFMK VIERTPSELA TCVYLCVNKL 

        70         80         90        100        110        120 
GPTYEGMELG IAEGALMKAI AQATGRKIDK LKEDLNQKGD LGLVAQMSRS NQRILFTPAP 

       130        140        150        160        170        180 
LTVTAVFHKL QDMAKTSGHM AMNKKVDMIK SLLVSCRDCE ARYLIRCLSG KLRIGLAEQS 

       190        200        210        220        230        240 
ILAALANAFT DFEIKKTGEK LSCEKMKERQ AEDILLLRST YSECPDYEKV VAAVLNGGLS 

       250        260        270        280        290        300 
KLPEKCKITP GIPVKPMLAH PTKGIAEVLK RFGGSVFACE FKYDGERAQI HYDSSGIKIF 

       310        320        330        340        350        360 
SRNQENNTDK YPDLKELLKQ IMDEETTSFI IDSEIVAFDP IHETILPFQI LSTRKRKNVG 

       370        380        390        400        410        420 
DSEIKVKVHV FMFDLLFWNG QSLTKSPYRK RREMLQRHFK EVGGVCGFVA SKDTEDTEQI 

       430        440        450        460        470        480 
SEFLDDAIKG NCEGLMIKTL DVDATYEIAK RSHSWLKLKK DYLDTIGDTV DLTVIGAFFG 

       490        500        510        520        530        540 
TGKRTGVYGG YLLACYNPIN EEYESICKIG TGLTDDDLRQ QHQYFEELRI EKARPYYSYD 

       550 
SSLKPDVWFD PK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DS239297 Genomic DNA. Translation: EDP34348.1.
RefSeqXP_001896804.1. XM_001896769.1.

3D structure databases

ProteinModelPortalA8PIP2.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6100253.
KEGGbmy:Bm1_26765.

Organism-specific databases

CTD6100253.

Phylogenomic databases

InParanoidA8PIP2.
KOK10747.

Family and domain databases

Gene3D1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00574. dnl1. 1 hit.
PROSITEPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA8PIP2_BRUMA
AccessionPrimary (citable) accession number: A8PIP2
Entry history
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: October 16, 2013
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)