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Protein

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Gene

CC1G_06084

Organism
Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003) (Inky cap fungus) (Hormographiella aspergillata)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

Succinate + a quinone = fumarate + a quinol.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes fumarate from succinate (eukaryal route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (CC1G_09250), Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (CC1G_06084)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes fumarate from succinate (eukaryal route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
Biological processElectron transportUniRule annotation, Transport, Tricarboxylic acid cycleUniRule annotation
LigandFADUniRule annotation, Flavoprotein

Enzyme and pathway databases

UniPathwayiUPA00223; UER01006

Names & Taxonomyi

Protein namesi
Recommended name:
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrialUniRule annotation (EC:1.3.5.1UniRule annotation)
Gene namesi
ORF Names:CC1G_06084Imported
OrganismiCoprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003) (Inky cap fungus) (Hormographiella aspergillata)Imported
Taxonomic identifieri240176 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaAgaricomycetesAgaricomycetidaeAgaricalesPsathyrellaceaeCoprinopsis
Proteomesi
  • UP000001861 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:CC1G_06084

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MembraneUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi240176.XP_001839894.1

Structurei

3D structure databases

ProteinModelPortaliA8PA35
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini52 – 447FAD_binding_2InterPro annotationAdd BLAST396
Domaini502 – 638Succ_DH_flav_CInterPro annotationAdd BLAST137

Sequence similaritiesi

Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.UniRule annotation

Keywords - Domaini

Transit peptideUniRule annotation

Phylogenomic databases

eggNOGiKOG2403 Eukaryota
COG1053 LUCA
InParanoidiA8PA35
KOiK00234
OrthoDBiEOG092C17LB

Family and domain databases

Gene3Di3.50.50.60, 2 hits
3.90.700.10, 1 hit
InterProiView protein in InterPro
IPR003953 FAD-binding_2
IPR036188 FAD/NAD-bd_sf
IPR003952 FRD_SDH_FAD_BS
IPR037099 Fum_R/Succ_DH_flav-like_C_sf
IPR015939 Fum_Rdtase/Succ_DH_flav-like_C
IPR027477 Succ_DH/fumarate_Rdtase_cat_sf
IPR011281 Succ_DH_flav_su_fwd
IPR014006 Succ_Dhase_FrdA_Gneg
PfamiView protein in Pfam
PF00890 FAD_binding_2, 1 hit
PF02910 Succ_DH_flav_C, 1 hit
SUPFAMiSSF46977 SSF46977, 1 hit
SSF51905 SSF51905, 2 hits
SSF56425 SSF56425, 1 hit
TIGRFAMsiTIGR01816 sdhA_forward, 1 hit
TIGR01812 sdhA_frdA_Gneg, 1 hit
PROSITEiView protein in PROSITE
PS00504 FRD_SDH_FAD_BINDING, 1 hit

Sequencei

Sequence statusi: Complete.

A8PA35-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLAARSVRRS LLGHARAFHA SSKVSRVVAT NPVKAQEVKG WGKYPLIEHE
60 70 80 90 100
YDAVVVGAGG AGLRAAFGLA EAGFKTACIT KLFPTRSHTV AAQGGINAAL
110 120 130 140 150
GNMTEDDWRW HMYDTVKGSD WLGDQDAIHY MCREAPNTVI ELEHFGVPFS
160 170 180 190 200
RTKEGKIYQR AFGGQSLKFG KGGQAYRCAA AADRTGHAIL HTLYGQSLRH
210 220 230 240 250
DTNFFIEYFA LDLIMQDGEC VGVIALNMED GTLHRFRAHK TVLATGGYGR
260 270 280 290 300
AYFSCTSAHT CSGDGNAMVA RAGLPQQDLE FVQFHPTGIY GAGCLITEGS
310 320 330 340 350
RGEGGYLLNS EGERFMERYA PTAKDLASRD VVSRSMTIEI REGRGVGPEK
360 370 380 390 400
DHIYLQLSHL PPDILHERLP GISETAAIFA GVDVTKEPIP VLPTVHYNMG
410 420 430 440 450
GIPTRYTGEV ITVDENGNDK VVPGLYAAGE AASVSVHGAN RLGANSLLDI
460 470 480 490 500
VVFGRAVAHH IRDTWTPGKP HKTIPEESGL ESIEFLDKIR RADGPEPTAK
510 520 530 540 550
IRLDLQKAMQ ADAAVFRTQE SLDEGVEKVR EIYNNFKNVG IKDRSMIWNS
560 570 580 590 600
DLVETLELRN LLQCAIQTIV SAAARKESRG AHAREDYPER DDENWMKHTL
610 620 630
SYQPDVESPD VKLAYRRVIE TTLDENECKP VPPFKRVY
Length:638
Mass (Da):70,251
Last modified:January 15, 2008 - v1
Checksum:iE3265800883FC51B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACS02000002 Genomic DNA Translation: EAU81873.1
RefSeqiXP_001839894.1, XM_001839842.2

Genome annotation databases

EnsemblFungiiEAU81873; EAU81873; CC1G_06084
GeneIDi6016517
KEGGicci:CC1G_06084

Similar proteinsi

Entry informationi

Entry nameiA8PA35_COPC7
AccessioniPrimary (citable) accession number: A8PA35
Entry historyiIntegrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: January 15, 2008
Last modified: March 28, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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