A8NTV6 (A8NTV6_BRUMA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Glutamate decarboxylase, 67 kDa isoform, putative EMBL EDP37739.1

Gene names

ORF Names:

Bm1_09745 EMBL EDP37739.1

Organism

Brugia malayi (Filarial nematode worm) [Complete proteome]

Taxonomic identifier

6279 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Nematoda › Chromadorea › Spirurida › Filarioidea › Onchocercidae › Brugia

Protein attributes

Sequence length	384 AA.
Sequence status	Fragment.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000382
Sequence similarities	Belongs to the group II decarboxylase family. RuleBase RU000382

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000382
Molecular function	Lyase RuleBase RU000382
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	carboxylic acid metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	carboxy-lyase activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	384	1	EMBL EDP37739.1

Sequences

	Sequence		Length	Mass (Da)
	A8NTV6 [UniParc]. Last modified January 15, 2008. Version 1. Checksum: 312FF2912BF9091E	FASTA	384	43,418
	10 20 30 40 50 60 MQSNNTSSST NLTKIYAAEL LPQNKRNWDS AKKFLEEIVK ILLEYINEEN QRENKILDFY 70 80 90 100 110 120 HPAEMQKLID LSIPDNPRTL HQLLQDCREV LRLGVRTGHP RFFNQISCGL DLVSMAGEWL 130 140 150 160 170 180 TATANTNMFT YEIAPVFILM EKEVTKKMAE LIGWQDSDAI FAPGGAISNL YAMNAARHSR 190 200 210 220 230 240 FPRCKPLGQS DLPTLCTFTS EDSHYSIKGA AAVMGIGTDN CFSIPTDPSG RMIPEALEQR 250 260 270 280 290 300 IIQCKKDGME PFFVCATAGT TVYGAWDPIP QIADICDRHK LWLHVDAAWG GGLLLSPEHR 310 320 330 340 350 360 HKLCGIERAN SVTWNPHKLM GALLQCSACF IKQEGLLFQT NQMSADYLFQ QDKPYDVSFD 370 380 TGDKAMQCGR HNDIFKLWLM WRSK

References

[1]

"Draft genome of the filarial nematode parasite Brugia malayi." Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E., Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T., Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L. , Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M., Pop M., White O., Barton G.J., Carlow C.K.S., Crawford M.J., Daub J., Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F., Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.-W., Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M.A., McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J., Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E., Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G., Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B., Blaxter M.L., Scott A.L. Science 317:1756-1760(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	DS237959 Genomic DNA. Translation: EDP37739.1.
RefSeq	XP_001893422.1. XM_001893387.1.
3D structure databases
ProteinModelPortal	A8NTV6.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6096882.
KEGG	bmy:Bm1_09745.
Organism-specific databases
CTD	6096882.
Phylogenomic databases
InParanoid	A8NTV6.
KO	K01580.
Family and domain databases
Gene3D	3.40.640.10. 1 hit.
InterPro	IPR002129. PyrdxlP-dep_de-COase. IPR015424. PyrdxlP-dep_Trfase. IPR015421. PyrdxlP-dep_Trfase_major_sub1. [Graphical view]
Pfam	PF00282. Pyridoxal_deC. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A8NTV6_BRUMA

Accession

Primary (citable) accession number: A8NTV6

Entry history

Integrated into UniProtKB/TrEMBL:	January 15, 2008
Last sequence update:	January 15, 2008
Last modified:	March 6, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)