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Protein
Submitted name:

Protein BM-SLI-1, isoform b

Gene

Bm-sli-1

Organism
Brugia malayi (Filarial nematode worm)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
  2. signal transducer activity Source: InterPro
  3. ubiquitin-protein transferase activity Source: InterPro
  4. zinc ion binding Source: InterPro

GO - Biological processi

  1. cell surface receptor signaling pathway Source: InterPro
  2. regulation of signaling Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Protein BM-SLI-1, isoform bImported
Gene namesi
Name:Bm-sli-1Imported
ORF Names:BM_Bm5061bImported
OrganismiBrugia malayi (Filarial nematode worm)Imported
Taxonomic identifieri6279 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaSpiruridaFilarioideaOnchocercidaeBrugia
ProteomesiUP000026912: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: InterPro
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliA8NML1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

InParanoidiA8NML1.

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
1.20.930.20. 1 hit.
3.30.40.10. 1 hit.
3.30.505.10. 1 hit.
InterProiIPR024162. Adaptor_Cbl.
IPR014741. Adaptor_Cbl_EF_hand-like.
IPR003153. Adaptor_Cbl_N_hlx.
IPR014742. Adaptor_Cbl_SH2-like.
IPR024159. Cbl_PTB.
IPR011992. EF-hand-dom_pair.
IPR000980. SH2.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
IPR017907. Znf_RING_CS.
[Graphical view]
PANTHERiPTHR23007. PTHR23007. 1 hit.
PfamiPF02262. Cbl_N. 1 hit.
PF02761. Cbl_N2. 1 hit.
PF02762. Cbl_N3. 1 hit.
[Graphical view]
SMARTiSM00184. RING. 1 hit.
SM00252. SH2. 1 hit.
[Graphical view]
SUPFAMiSSF47668. SSF47668. 1 hit.
SSF55550. SSF55550. 1 hit.
PROSITEiPS51506. CBL_PTB. 1 hit.
PS00518. ZF_RING_1. 1 hit.
PS50089. ZF_RING_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8NML1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLSAMVVGYV DMIVGSFVRI ITGIEWKVGN NHSWILPEGV TESGKYIRQP
60 70 80 90 100
NFAHQMAVSG FASSILNKIH EIVSGGAVSI LHSYNGRSDT VAGPSNMMQI
110 120 130 140 150
QDRRLVEKTF KLMDTVVKHC QQPRLNLKNS PPFILDILPD TYHQLSTIIS
160 170 180 190 200
KNPNVLKDNT YLVLFLENVQ SKCKQTMKLF KEDRERIYDE RSAARRNLTK
210 220 230 240 250
LSLIFSHMLA ELKAEFPDGH FIGENFRITK KEADAFWRES FGIKTTVPWF
260 270 280 290 300
EFRIALSKVH RLNTGLETLA LKTTIDLTVN EHISNFEFDV FTRLFQPWNT
310 320 330 340 350
LLHNWQLLAV THPGYVAFLT YDEVKQKLQK YSNKPGSYVF RLSCTRLGQW
360 370 380 390 400
AVGYVAPDGK IYQTIPQNKS LIQALVDGSR EGFYRFPDGR PTNPDLSHAL
410 420 430 440 450
QPSPEGRVKV TPEQYQIYCE MGTTFEMCKI CAENNKNVKL EPCGHLLCTP
460 470 480 490 500
CLQSWQESDG GGTCPFCRCE IKGTERIIID SFDPIEANKK LGYETIIEKS
510 520 530 540 550
TVKNVRQSWP PRSEAVPPRR APPLPPRYDS SSAGNSPSVT HKQLIFDVPI
560 570 580 590 600
ASNNNMSTHN EGKLDQTRND AIPNSTSQLK VLAPTTTEGS SYVNVVTSGG
610
KSNYEGLQYV NTAVINGQT
Length:619
Mass (Da):69,769
Last modified:July 9, 2014 - v2
Checksum:i2090541133572332
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HF574788 Genomic DNA. Translation: CDQ05117.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HF574788 Genomic DNA. Translation: CDQ05117.1.

3D structure databases

ProteinModelPortaliA8NML1.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

InParanoidiA8NML1.

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
1.20.930.20. 1 hit.
3.30.40.10. 1 hit.
3.30.505.10. 1 hit.
InterProiIPR024162. Adaptor_Cbl.
IPR014741. Adaptor_Cbl_EF_hand-like.
IPR003153. Adaptor_Cbl_N_hlx.
IPR014742. Adaptor_Cbl_SH2-like.
IPR024159. Cbl_PTB.
IPR011992. EF-hand-dom_pair.
IPR000980. SH2.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
IPR017907. Znf_RING_CS.
[Graphical view]
PANTHERiPTHR23007. PTHR23007. 1 hit.
PfamiPF02262. Cbl_N. 1 hit.
PF02761. Cbl_N2. 1 hit.
PF02762. Cbl_N3. 1 hit.
[Graphical view]
SMARTiSM00184. RING. 1 hit.
SM00252. SH2. 1 hit.
[Graphical view]
SUPFAMiSSF47668. SSF47668. 1 hit.
SSF55550. SSF55550. 1 hit.
PROSITEiPS51506. CBL_PTB. 1 hit.
PS00518. ZF_RING_1. 1 hit.
PS50089. ZF_RING_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Ghedin E.
    Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiA8NML1_BRUMA
AccessioniPrimary (citable) accession number: A8NML1
Entry historyi
Integrated into UniProtKB/TrEMBL: January 15, 2008
Last sequence update: July 9, 2014
Last modified: January 7, 2015
This is version 47 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.