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Protein

Histone-lysine N-methyltransferase

Gene

CC1G_09124

Organism
Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003) (Inky cap fungus) (Hormographiella aspergillata)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

GO - Molecular functioni

  1. histone methyltransferase activity (H3-K36 specific) Source: InterPro

GO - Biological processi

  1. DNA-templated transcription, elongation Source: InterPro
  2. regulation of transcription, DNA-templated Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotation, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone-lysine N-methyltransferaseSAAS annotation (EC:2.1.1.43SAAS annotation)
Gene namesi
ORF Names:CC1G_09124Imported
OrganismiCoprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003) (Inky cap fungus) (Hormographiella aspergillata)Imported
Taxonomic identifieri240176 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaAgaricomycetesAgaricomycetidaeAgaricalesPsathyrellaceaeCoprinopsis
ProteomesiUP000001861 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

  1. chromosome Source: InterPro
  2. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation

Phylogenomic databases

InParanoidiA8NJ83.
KOiK11423.
OrthoDBiEOG7P8PH3.

Family and domain databases

InterProiIPR006560. AWS_dom.
IPR025788. Hist-Lys_N-MeTrfase_SET2_fun.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR013257. SRI.
[Graphical view]
PfamiPF00856. SET. 1 hit.
PF08236. SRI. 1 hit.
[Graphical view]
SMARTiSM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEiPS51215. AWS. 1 hit.
PS50868. POST_SET. 1 hit.
PS51568. SAM_MT43_SET2_1. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8NJ83-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAAATDNYP VSSDTLATDT NMALDTVQPG LEGEPMSVDV KPDLNLKTED
60 70 80 90 100
SLVPPSTSLA DLDMKGEKSD SSSSLNGSPN ESSKSSSPTA TSSKPQKAST
110 120 130 140 150
PGPQLIGDLP IAREDALKTF NEIPFNNYQF KSLGRSRESV LKTFAPCVDN
160 170 180 190 200
EDNACGPYSD CINRLTQVEC LPEDCRCRSH CQNQRFQKRQ YANIEIVLTE
210 220 230 240 250
KKGYGLRAED DIPKDSFIYE YVGDVVSPNS FKKRMREYAE EGIQHFYFMM
260 270 280 290 300
LQKDEFIDAT KSGGIGRFAN HSCNPNCYVA KWTVGDHVRM GIFSKRLIRK
310 320 330 340 350
HEELTFNYNV DRYGHQAQTC YCGEPNCIGF IGGKTQTDVA TMDDLYLDAL
360 370 380 390 400
GITDEDDVAA LKGTKKKKGK KIDDPDFMPS VKPIVEKEVP KVVQAIRQTS
410 420 430 440 450
NRKVLYKLLT RIKITDDQAA LRQIMRLRGY SVMKNVLEDY VADLDLVELV
460 470 480 490 500
LQCLESWPLL NRNKVDDSQI MTSVEGHATS ERESLQALAK KLMEHWQSLP
510 520 530 540 550
LYNRIPKRAL PQDDGPSKDK PDTPTLDPYE EQIKRRRQEE EQKLRWVRIR
560 570 580 590 600
AQQLEREKQQ RQFREHQRGL VKDLYDPFPP QPQKPSVDTS SKMQEMLKAI
610 620 630 640 650
IANATETVAA EEKRKAEEAE AKAKAEAAAA EKAARRKARA AAKKAMTPEE
660 670 680 690 700
KEALKEKRLM KLIGAVVVKS MSKYARGLQK DYFKKYAKEL TQVITEKEKK
710 720 730 740 750
SSSYKEGRLE SLSEEKVAKI KKFSKDYIAK VLRKLEKAGK YSSQSSRATT
760 770 780 790 800
EQTGASSSTH TQTPNSLDGG DGSINGGGEV PMSVEEAMDM EEDSDVDADG
810 820
SVAGDEEQRR AFRNGDGRED GSKTMK
Length:826
Mass (Da):92,686
Last modified:August 9, 2010 - v2
Checksum:iB0D3C7006807D734
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACS02000010 Genomic DNA. Translation: EAU87663.2.
RefSeqiXP_001834167.2. XM_001834115.2.

Genome annotation databases

GeneIDi6010673.
KEGGicci:CC1G_09124.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACS02000010 Genomic DNA. Translation: EAU87663.2.
RefSeqiXP_001834167.2. XM_001834115.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi6010673.
KEGGicci:CC1G_09124.

Phylogenomic databases

InParanoidiA8NJ83.
KOiK11423.
OrthoDBiEOG7P8PH3.

Family and domain databases

InterProiIPR006560. AWS_dom.
IPR025788. Hist-Lys_N-MeTrfase_SET2_fun.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR013257. SRI.
[Graphical view]
PfamiPF00856. SET. 1 hit.
PF08236. SRI. 1 hit.
[Graphical view]
SMARTiSM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEiPS51215. AWS. 1 hit.
PS50868. POST_SET. 1 hit.
PS51568. SAM_MT43_SET2_1. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Insights into evolution of multicellular fungi from the assembled chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus)."
    Stajich J.E., Wilke S.K., Ahren D., Au C.H., Birren B.W., Borodovsky M., Burns C., Canback B., Casselton L.A., Cheng C.K., Deng J., Dietrich F.S., Fargo D.C., Farman M.L., Gathman A.C., Goldberg J., Guigo R., Hoegger P.J.
    , Hooker J.B., Huggins A., James T.Y., Kamada T., Kilaru S., Kodira C., Kues U., Kupfer D., Kwan H.S., Lomsadze A., Li W., Lilly W.W., Ma L.J., Mackey A.J., Manning G., Martin F., Muraguchi H., Natvig D.O., Palmerini H., Ramesh M.A., Rehmeyer C.J., Roe B.A., Shenoy N., Stanke M., Ter-Hovhannisyan V., Tunlid A., Velagapudi R., Vision T.J., Zeng Q., Zolan M.E., Pukkila P.J.
    Proc. Natl. Acad. Sci. U.S.A. 107:11889-11894(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003Imported.

Entry informationi

Entry nameiA8NJ83_COPC7
AccessioniPrimary (citable) accession number: A8NJ83
Entry historyi
Integrated into UniProtKB/TrEMBL: January 14, 2008
Last sequence update: August 9, 2010
Last modified: March 3, 2015
This is version 44 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.