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A8MZ97

- CB074_HUMAN

UniProt

A8MZ97 - CB074_HUMAN

Protein

Uncharacterized protein C2orf74

Gene

C2orf74

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 48 (01 Oct 2014)
      Sequence version 3 (24 Nov 2009)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uncharacterized protein C2orf74
    Gene namesi
    Name:C2orf74
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 2

    Organism-specific databases

    HGNCiHGNC:34439. C2orf74.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA162379547.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 194194Uncharacterized protein C2orf74PRO_0000343566Add
    BLAST

    Proteomic databases

    PaxDbiA8MZ97.
    PRIDEiA8MZ97.

    PTM databases

    PhosphoSiteiA8MZ97.

    Expressioni

    Gene expression databases

    BgeeiA8MZ97.
    CleanExiHS_C2orf74.
    GenevestigatoriA8MZ97.

    Organism-specific databases

    HPAiHPA026826.

    Interactioni

    Protein-protein interaction databases

    BioGridi130940. 2 interactions.
    IntActiA8MZ97. 1 interaction.

    Structurei

    3D structure databases

    ProteinModelPortaliA8MZ97.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei15 – 3521HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG43234.
    HOGENOMiHOG000111333.
    HOVERGENiHBG107583.
    InParanoidiA8MZ97.
    OMAiDHERRVI.
    OrthoDBiEOG70W3GF.
    PhylomeDBiA8MZ97.

    Family and domain databases

    InterProiIPR027813. DUF4642.
    [Graphical view]
    PfamiPF15484. DUF4642. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A8MZ97-1 [UniParc]FASTAAdd to Basket

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    MSLLAKPMSF ETTAITFFII LLICLICILL LLVVFLYKCF QGRKGKETKK    50
    VPCTDANGGV DCAAAKVVTS NPEDHERILM QVMNLNVPMR PGILVQRQSK 100
    EVLATPLENR RDMEAEEENQ INEKQEPENA GETGQEEDDG LQKIHTSVTR 150
    TPSVVESQKR PLKGVTFSRE VIVVDLGNEY PTPRSYTREH KERK 194
    Length:194
    Mass (Da):21,915
    Last modified:November 24, 2009 - v3
    Checksum:iDD90134F5F912145
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC016747 Genomic DNA. No translation available.
    RefSeqiNP_001137431.1. NM_001143959.1.
    XP_005264344.1. XM_005264287.2.
    UniGeneiHs.140617.

    Genome annotation databases

    EnsembliENST00000432605; ENSP00000402915; ENSG00000237651.
    GeneIDi339804.
    KEGGihsa:339804.
    UCSCiuc010ypl.1. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC016747 Genomic DNA. No translation available.
    RefSeqi NP_001137431.1. NM_001143959.1.
    XP_005264344.1. XM_005264287.2.
    UniGenei Hs.140617.

    3D structure databases

    ProteinModelPortali A8MZ97.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 130940. 2 interactions.
    IntActi A8MZ97. 1 interaction.

    PTM databases

    PhosphoSitei A8MZ97.

    Proteomic databases

    PaxDbi A8MZ97.
    PRIDEi A8MZ97.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000432605 ; ENSP00000402915 ; ENSG00000237651 .
    GeneIDi 339804.
    KEGGi hsa:339804.
    UCSCi uc010ypl.1. human.

    Organism-specific databases

    CTDi 339804.
    GeneCardsi GC02P061372.
    HGNCi HGNC:34439. C2orf74.
    HPAi HPA026826.
    neXtProti NX_A8MZ97.
    PharmGKBi PA162379547.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG43234.
    HOGENOMi HOG000111333.
    HOVERGENi HBG107583.
    InParanoidi A8MZ97.
    OMAi DHERRVI.
    OrthoDBi EOG70W3GF.
    PhylomeDBi A8MZ97.

    Miscellaneous databases

    GenomeRNAii 339804.
    NextBioi 97553.

    Gene expression databases

    Bgeei A8MZ97.
    CleanExi HS_C2orf74.
    Genevestigatori A8MZ97.

    Family and domain databases

    InterProi IPR027813. DUF4642.
    [Graphical view ]
    Pfami PF15484. DUF4642. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
      , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
      Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiCB074_HUMAN
    AccessioniPrimary (citable) accession number: A8MZ97
    Secondary accession number(s): C9JP62
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 1, 2008
    Last sequence update: November 24, 2009
    Last modified: October 1, 2014
    This is version 48 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 2
      Human chromosome 2: entries, gene names and cross-references to MIM

    External Data

    Dasty 3