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A8MZ97

- CB074_HUMAN

UniProt

A8MZ97 - CB074_HUMAN

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Protein

Uncharacterized protein C2orf74

Gene

C2orf74

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C2orf74
Gene namesi
Name:C2orf74
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 2

Organism-specific databases

HGNCiHGNC:34439. C2orf74.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei15 – 3521HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162379547.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 194194Uncharacterized protein C2orf74PRO_0000343566Add
BLAST

Proteomic databases

MaxQBiA8MZ97.
PaxDbiA8MZ97.
PRIDEiA8MZ97.

PTM databases

PhosphoSiteiA8MZ97.

Expressioni

Gene expression databases

BgeeiA8MZ97.
CleanExiHS_C2orf74.
ExpressionAtlasiA8MZ97. baseline.
GenevestigatoriA8MZ97.

Organism-specific databases

HPAiHPA026826.

Interactioni

Protein-protein interaction databases

BioGridi130940. 2 interactions.
IntActiA8MZ97. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliA8MZ97.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG43234.
GeneTreeiENSGT00390000004911.
HOGENOMiHOG000111333.
HOVERGENiHBG107583.
InParanoidiA8MZ97.
OMAiDHERRVI.
OrthoDBiEOG70W3GF.
PhylomeDBiA8MZ97.

Family and domain databases

InterProiIPR027813. DUF4642.
[Graphical view]
PfamiPF15484. DUF4642. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8MZ97-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSLLAKPMSF ETTAITFFII LLICLICILL LLVVFLYKCF QGRKGKETKK
60 70 80 90 100
VPCTDANGGV DCAAAKVVTS NPEDHERILM QVMNLNVPMR PGILVQRQSK
110 120 130 140 150
EVLATPLENR RDMEAEEENQ INEKQEPENA GETGQEEDDG LQKIHTSVTR
160 170 180 190
TPSVVESQKR PLKGVTFSRE VIVVDLGNEY PTPRSYTREH KERK
Length:194
Mass (Da):21,915
Last modified:November 24, 2009 - v3
Checksum:iDD90134F5F912145
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC016747 Genomic DNA. No translation available.
RefSeqiNP_001137431.1. NM_001143959.1.
XP_005264344.1. XM_005264287.2.
UniGeneiHs.140617.

Genome annotation databases

EnsembliENST00000432605; ENSP00000402915; ENSG00000237651.
GeneIDi339804.
KEGGihsa:339804.
UCSCiuc010ypl.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC016747 Genomic DNA. No translation available.
RefSeqi NP_001137431.1. NM_001143959.1.
XP_005264344.1. XM_005264287.2.
UniGenei Hs.140617.

3D structure databases

ProteinModelPortali A8MZ97.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 130940. 2 interactions.
IntActi A8MZ97. 1 interaction.

PTM databases

PhosphoSitei A8MZ97.

Proteomic databases

MaxQBi A8MZ97.
PaxDbi A8MZ97.
PRIDEi A8MZ97.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000432605 ; ENSP00000402915 ; ENSG00000237651 .
GeneIDi 339804.
KEGGi hsa:339804.
UCSCi uc010ypl.1. human.

Organism-specific databases

CTDi 339804.
GeneCardsi GC02P061372.
HGNCi HGNC:34439. C2orf74.
HPAi HPA026826.
neXtProti NX_A8MZ97.
PharmGKBi PA162379547.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG43234.
GeneTreei ENSGT00390000004911.
HOGENOMi HOG000111333.
HOVERGENi HBG107583.
InParanoidi A8MZ97.
OMAi DHERRVI.
OrthoDBi EOG70W3GF.
PhylomeDBi A8MZ97.

Miscellaneous databases

ChiTaRSi C2orf74. human.
GenomeRNAii 339804.
NextBioi 97553.

Gene expression databases

Bgeei A8MZ97.
CleanExi HS_C2orf74.
ExpressionAtlasi A8MZ97. baseline.
Genevestigatori A8MZ97.

Family and domain databases

InterProi IPR027813. DUF4642.
[Graphical view ]
Pfami PF15484. DUF4642. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiCB074_HUMAN
AccessioniPrimary (citable) accession number: A8MZ97
Secondary accession number(s): C9JP62
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 2008
Last sequence update: November 24, 2009
Last modified: November 26, 2014
This is version 50 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM

External Data

Dasty 3