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Protein

EF-hand calcium-binding domain-containing protein 9

Gene

EFCAB9

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
EF-hand calcium-binding domain-containing protein 9
Gene namesi
Name:EFCAB9
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 5

Organism-specific databases

HGNCiHGNC:34530. EFCAB9.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA164718963.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 197197EF-hand calcium-binding domain-containing protein 9PRO_0000340648Add
BLAST

Proteomic databases

PRIDEiA8MZ26.

PTM databases

PhosphoSiteiA8MZ26.

Expressioni

Gene expression databases

BgeeiA8MZ26.
GenevestigatoriA8MZ26.

Organism-specific databases

HPAiHPA056274.

Structurei

3D structure databases

ProteinModelPortaliA8MZ26.
SMRiA8MZ26. Positions 28-167.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini59 – 9436EF-hand 1PROSITE-ProRule annotationAdd
BLAST
Domaini136 – 17136EF-hand 2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 2 EF-hand domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiNOG324011.
GeneTreeiENSGT00390000007501.
HOGENOMiHOG000112340.
HOVERGENiHBG107838.
InParanoidiA8MZ26.
OMAiKQGSFLW.
OrthoDBiEOG74FF2R.
PhylomeDBiA8MZ26.
TreeFamiTF328944.

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
InterProiIPR011992. EF-hand-dom_pair.
IPR002048. EF_hand_dom.
[Graphical view]
PROSITEiPS50222. EF_HAND_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8MZ26-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRLKQGSFLW YLYLDKIYCL LSVRNVKALA EYFHILDVHG KNTLNDVLFY
60 70 80 90 100
HFLHHVTDLK KAQINIVFDM LDWNAVGEID FEKFYMLVCM LLAHQNHLEG
110 120 130 140 150
QFMYRHSRPV FDLLDLKGDL RIGAKNFEMY RFLFNIQKQE LKDLFRDFDI
160 170 180 190
TGDNRLNYQE FKLYTIIYTD KLQKRQKTEE KEKGERKRSL YSKCHIK
Length:197
Mass (Da):23,937
Last modified:June 10, 2008 - v2
Checksum:i248012FD9746D508
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC024561 Genomic DNA. No translation available.
CCDSiCCDS54946.1.
RefSeqiNP_001164654.1. NM_001171183.1.
UniGeneiHs.716824.

Genome annotation databases

EnsembliENST00000398186; ENSP00000381247; ENSG00000214360.
GeneIDi285588.
KEGGihsa:285588.
UCSCiuc021yhr.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC024561 Genomic DNA. No translation available.
CCDSiCCDS54946.1.
RefSeqiNP_001164654.1. NM_001171183.1.
UniGeneiHs.716824.

3D structure databases

ProteinModelPortaliA8MZ26.
SMRiA8MZ26. Positions 28-167.
ModBaseiSearch...
MobiDBiSearch...

PTM databases

PhosphoSiteiA8MZ26.

Proteomic databases

PRIDEiA8MZ26.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000398186; ENSP00000381247; ENSG00000214360.
GeneIDi285588.
KEGGihsa:285588.
UCSCiuc021yhr.1. human.

Organism-specific databases

CTDi285588.
GeneCardsiGC05P171554.
HGNCiHGNC:34530. EFCAB9.
HPAiHPA056274.
neXtProtiNX_A8MZ26.
PharmGKBiPA164718963.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiNOG324011.
GeneTreeiENSGT00390000007501.
HOGENOMiHOG000112340.
HOVERGENiHBG107838.
InParanoidiA8MZ26.
OMAiKQGSFLW.
OrthoDBiEOG74FF2R.
PhylomeDBiA8MZ26.
TreeFamiTF328944.

Miscellaneous databases

GenomeRNAii285588.
NextBioi95620.
PROiA8MZ26.

Gene expression databases

BgeeiA8MZ26.
GenevestigatoriA8MZ26.

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
InterProiIPR011992. EF-hand-dom_pair.
IPR002048. EF_hand_dom.
[Graphical view]
PROSITEiPS50222. EF_HAND_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The DNA sequence and comparative analysis of human chromosome 5."
    Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S., Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M., She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.
    , Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.
    Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiEFCB9_HUMAN
AccessioniPrimary (citable) accession number: A8MZ26
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: June 10, 2008
Last modified: January 7, 2015
This is version 62 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.