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Protein

Inactive ubiquitin carboxyl-terminal hydrolase MINDY-4B

Gene

MINDY4B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

In contrast to other members of the MINDY family, lacks the conserved active sites required for deubiquitination.Curated

Names & Taxonomyi

Protein namesi
Recommended name:
Inactive ubiquitin carboxyl-terminal hydrolase MINDY-4B
Alternative name(s):
Protein FAM188B2
Gene namesi
Name:MINDY4BImported
Synonyms:C3orf76, FAM188B2
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

HGNCiHGNC:35475 MINDY4B
neXtProtiNX_A8MYZ0

Pathology & Biotechi

Organism-specific databases

DisGeNETi646951
OpenTargetsiENSG00000214237
PharmGKBiPA165697258

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003435731 – 460Inactive ubiquitin carboxyl-terminal hydrolase MINDY-4BAdd BLAST460

Proteomic databases

PaxDbiA8MYZ0
PRIDEiA8MYZ0

PTM databases

iPTMnetiA8MYZ0
PhosphoSitePlusiA8MYZ0

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG2871 Eukaryota
ENOG410XSGV LUCA
GeneTreeiENSGT00530000063283
InParanoidiA8MYZ0
PhylomeDBiA8MYZ0

Family and domain databases

InterProiView protein in InterPro
IPR025257 DUF4205
PfamiView protein in Pfam
PF13898 DUF4205, 1 hit
SMARTiView protein in SMART
SM01174 DUF4205, 1 hit

Sequencei

Sequence statusi: Complete.

A8MYZ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDMEVLGQEQ SSEQLDLEEI SRKISFLDKW REIFSYHRLG TNNSTPQNHE
60 70 80 90 100
GNHTSADENE DGTGLSQPKG QGHLPSSGLC SIPNPSIISS KLGGFPISLA
110 120 130 140 150
MATKLRQILF GNTVHVFSYN WKKAYFRFHD PSSELAFTLE VGKGGARSIQ
160 170 180 190 200
MAVQGSIIKY LLFTRKGKDC NLGNLCEISK KEQEQALAAA LAGILWAAGA
210 220 230 240 250
AQKATICLVT EDIYVASTPD YSVDNFTERL QLFEFLEKEA AEKFIYDHLL
260 270 280 290 300
CFRGEGSHGV ILFLYSLIFS RTFERLQMDL DVTTTQLLQP NAGGFLCRQA
310 320 330 340 350
VLNMILTGRA SPNVFNGCEE GKSQETLHGV LTRSDVGYLQ WGKDASEDDR
360 370 380 390 400
LSQVGSMLKT PKLPIWLCNI NGNYSILFCT NRQLLSDWKM ERLFDLYFYS
410 420 430 440 450
GQPSQKKLVR LTIDTHSHHW ERDQQEEKHG PRRRFSPVEM AIRTKWSEAT
460
INWNGTVPFF
Length:460
Mass (Da):51,976
Last modified:March 28, 2018 - v3
Checksum:i01C819A64DC43DB0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC016142 Genomic DNA No translation available.
AC020636 Genomic DNA No translation available.
AC108674 Genomic DNA No translation available.
UniGeneiHs.380222
Hs.739058

Genome annotation databases

EnsembliENST00000465419; ENSP00000491923; ENSG00000214237

Similar proteinsi

Entry informationi

Entry nameiMIY4B_HUMAN
AccessioniPrimary (citable) accession number: A8MYZ0
Secondary accession number(s): A0A1W2PQ44
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: March 28, 2018
Last modified: May 23, 2018
This is version 52 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. Peptidase families
    Classification of peptidase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

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