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A8MYV0

- DCD2C_HUMAN

UniProt

A8MYV0 - DCD2C_HUMAN

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Protein

Doublecortin domain-containing protein 2C

Gene

DCDC2C

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 1 out of 5- Protein inferred from homologyi

Functioni

GO - Biological processi

  1. intracellular signal transduction Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Doublecortin domain-containing protein 2C
Gene namesi
Name:DCDC2C
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 2

Organism-specific databases

HGNCiHGNC:32696. DCDC2C.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 355355Doublecortin domain-containing protein 2CPRO_0000344449Add
BLAST

Proteomic databases

PaxDbiA8MYV0.
PRIDEiA8MYV0.

PTM databases

PhosphoSiteiA8MYV0.

Expressioni

Gene expression databases

BgeeiA8MYV0.
ExpressionAtlasiA8MYV0. baseline.
GenevestigatoriA8MYV0.

Organism-specific databases

HPAiHPA045848.

Structurei

3D structure databases

ProteinModelPortaliA8MYV0.
SMRiA8MYV0. Positions 15-97, 138-216.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini16 – 9883Doublecortin 1PROSITE-ProRule annotationAdd
BLAST
Domaini136 – 21782Doublecortin 2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 2 doublecortin domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiNOG116978.
InParanoidiA8MYV0.
PhylomeDBiA8MYV0.

Family and domain databases

Gene3Di3.10.20.230. 2 hits.
InterProiIPR003533. Doublecortin_dom.
[Graphical view]
PfamiPF03607. DCX. 2 hits.
[Graphical view]
SMARTiSM00537. DCX. 2 hits.
[Graphical view]
PROSITEiPS50309. DC. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8MYV0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGTRGPSAPV DTTPAKTIVV YRNGDPFYVG KKFVLSRRRA ATFEALLEQL
60 70 80 90 100
TEQVDVPFGV RRLFTPTRGH RVLGLDALQA GGKYVAAGRE RFKELDYIHI
110 120 130 140 150
VPRKPAKIRK LKEIKPVVHC DINVPSKWQT YHRISRHINV FTNGRLFIPP
160 170 180 190 200
AKIIIPKFSL SDWDIVLATI GEKVFPLGGV RKLFTMNGHL LGDSKDLQDN
210 220 230 240 250
HFYVAVGLET FKYFPYWKSP RVPSEVQQRY ANVEKNSQRK KKVDSKGKEP
260 270 280 290 300
CKYDGIPPKT QDSVYYAKEE KKKTLAEPLV QRGAEGDVYK APTPSKETQG
310 320 330 340 350
ALDVKEEHNV QLEVPVDQAE SSCDKHCCHN FAYNKHIHKF WLPVILISID

FEAVE
Length:355
Mass (Da):40,425
Last modified:February 8, 2011 - v3
Checksum:iAC2BD3EDED18C794
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC010907 Genomic DNA. No translation available.
AC019172 Genomic DNA. No translation available.
UniGeneiHs.304233.
Hs.631689.

Genome annotation databases

EnsembliENST00000399143; ENSP00000382097; ENSG00000214866.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC010907 Genomic DNA. No translation available.
AC019172 Genomic DNA. No translation available.
UniGenei Hs.304233.
Hs.631689.

3D structure databases

ProteinModelPortali A8MYV0.
SMRi A8MYV0. Positions 15-97, 138-216.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei A8MYV0.

Proteomic databases

PaxDbi A8MYV0.
PRIDEi A8MYV0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000399143 ; ENSP00000382097 ; ENSG00000214866 .

Organism-specific databases

GeneCardsi GC02P003750.
HGNCi HGNC:32696. DCDC2C.
HPAi HPA045848.
neXtProti NX_A8MYV0.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG116978.
InParanoidi A8MYV0.
PhylomeDBi A8MYV0.

Miscellaneous databases

PROi A8MYV0.

Gene expression databases

Bgeei A8MYV0.
ExpressionAtlasi A8MYV0. baseline.
Genevestigatori A8MYV0.

Family and domain databases

Gene3Di 3.10.20.230. 2 hits.
InterProi IPR003533. Doublecortin_dom.
[Graphical view ]
Pfami PF03607. DCX. 2 hits.
[Graphical view ]
SMARTi SM00537. DCX. 2 hits.
[Graphical view ]
PROSITEi PS50309. DC. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiDCD2C_HUMAN
AccessioniPrimary (citable) accession number: A8MYV0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: February 8, 2011
Last modified: October 29, 2014
This is version 43 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3