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A8MYV0

- DCD2C_HUMAN

UniProt

A8MYV0 - DCD2C_HUMAN

Protein

Doublecortin domain-containing protein 2C

Gene

DCDC2C

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 1 out of 5- Protein inferred from homologyi
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    • History
      Entry version 42 (01 Oct 2014)
      Sequence version 3 (08 Feb 2011)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. intracellular signal transduction Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Doublecortin domain-containing protein 2C
    Gene namesi
    Name:DCDC2C
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 2

    Organism-specific databases

    HGNCiHGNC:32696. DCDC2C.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 355355Doublecortin domain-containing protein 2CPRO_0000344449Add
    BLAST

    Proteomic databases

    PaxDbiA8MYV0.
    PRIDEiA8MYV0.

    PTM databases

    PhosphoSiteiA8MYV0.

    Expressioni

    Gene expression databases

    BgeeiA8MYV0.
    GenevestigatoriA8MYV0.

    Organism-specific databases

    HPAiHPA045848.

    Structurei

    3D structure databases

    ProteinModelPortaliA8MYV0.
    SMRiA8MYV0. Positions 15-97, 138-216.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini16 – 9883Doublecortin 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini136 – 21782Doublecortin 2PROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 2 doublecortin domains.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat

    Phylogenomic databases

    eggNOGiNOG116978.
    InParanoidiA8MYV0.
    PhylomeDBiA8MYV0.

    Family and domain databases

    Gene3Di3.10.20.230. 2 hits.
    InterProiIPR003533. Doublecortin_dom.
    [Graphical view]
    PfamiPF03607. DCX. 2 hits.
    [Graphical view]
    SMARTiSM00537. DCX. 2 hits.
    [Graphical view]
    PROSITEiPS50309. DC. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A8MYV0-1 [UniParc]FASTAAdd to Basket

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    MGTRGPSAPV DTTPAKTIVV YRNGDPFYVG KKFVLSRRRA ATFEALLEQL    50
    TEQVDVPFGV RRLFTPTRGH RVLGLDALQA GGKYVAAGRE RFKELDYIHI 100
    VPRKPAKIRK LKEIKPVVHC DINVPSKWQT YHRISRHINV FTNGRLFIPP 150
    AKIIIPKFSL SDWDIVLATI GEKVFPLGGV RKLFTMNGHL LGDSKDLQDN 200
    HFYVAVGLET FKYFPYWKSP RVPSEVQQRY ANVEKNSQRK KKVDSKGKEP 250
    CKYDGIPPKT QDSVYYAKEE KKKTLAEPLV QRGAEGDVYK APTPSKETQG 300
    ALDVKEEHNV QLEVPVDQAE SSCDKHCCHN FAYNKHIHKF WLPVILISID 350
    FEAVE 355
    Length:355
    Mass (Da):40,425
    Last modified:February 8, 2011 - v3
    Checksum:iAC2BD3EDED18C794
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC010907 Genomic DNA. No translation available.
    AC019172 Genomic DNA. No translation available.
    UniGeneiHs.304233.
    Hs.631689.

    Genome annotation databases

    EnsembliENST00000399143; ENSP00000382097; ENSG00000214866.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC010907 Genomic DNA. No translation available.
    AC019172 Genomic DNA. No translation available.
    UniGenei Hs.304233.
    Hs.631689.

    3D structure databases

    ProteinModelPortali A8MYV0.
    SMRi A8MYV0. Positions 15-97, 138-216.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei A8MYV0.

    Proteomic databases

    PaxDbi A8MYV0.
    PRIDEi A8MYV0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000399143 ; ENSP00000382097 ; ENSG00000214866 .

    Organism-specific databases

    GeneCardsi GC02P003750.
    HGNCi HGNC:32696. DCDC2C.
    HPAi HPA045848.
    neXtProti NX_A8MYV0.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG116978.
    InParanoidi A8MYV0.
    PhylomeDBi A8MYV0.

    Miscellaneous databases

    PROi A8MYV0.

    Gene expression databases

    Bgeei A8MYV0.
    Genevestigatori A8MYV0.

    Family and domain databases

    Gene3Di 3.10.20.230. 2 hits.
    InterProi IPR003533. Doublecortin_dom.
    [Graphical view ]
    Pfami PF03607. DCX. 2 hits.
    [Graphical view ]
    SMARTi SM00537. DCX. 2 hits.
    [Graphical view ]
    PROSITEi PS50309. DC. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
      , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
      Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiDCD2C_HUMAN
    AccessioniPrimary (citable) accession number: A8MYV0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 22, 2008
    Last sequence update: February 8, 2011
    Last modified: October 1, 2014
    This is version 42 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 2
      Human chromosome 2: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3