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A8MYV0 (DCD2C_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Doublecortin domain-containing protein 2C
Gene names
Name:DCDC2C
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length355 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Sequence similarities

Contains 2 doublecortin domains.

Ontologies

Keywords
   DomainRepeat
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processintracellular signal transduction

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 355355Doublecortin domain-containing protein 2C
PRO_0000344449

Regions

Domain16 – 9883Doublecortin 1
Domain136 – 21782Doublecortin 2

Sequences

Sequence LengthMass (Da)Tools
A8MYV0 [UniParc].

Last modified February 8, 2011. Version 3.
Checksum: AC2BD3EDED18C794

FASTA35540,425
        10         20         30         40         50         60 
MGTRGPSAPV DTTPAKTIVV YRNGDPFYVG KKFVLSRRRA ATFEALLEQL TEQVDVPFGV 

        70         80         90        100        110        120 
RRLFTPTRGH RVLGLDALQA GGKYVAAGRE RFKELDYIHI VPRKPAKIRK LKEIKPVVHC 

       130        140        150        160        170        180 
DINVPSKWQT YHRISRHINV FTNGRLFIPP AKIIIPKFSL SDWDIVLATI GEKVFPLGGV 

       190        200        210        220        230        240 
RKLFTMNGHL LGDSKDLQDN HFYVAVGLET FKYFPYWKSP RVPSEVQQRY ANVEKNSQRK 

       250        260        270        280        290        300 
KKVDSKGKEP CKYDGIPPKT QDSVYYAKEE KKKTLAEPLV QRGAEGDVYK APTPSKETQG 

       310        320        330        340        350 
ALDVKEEHNV QLEVPVDQAE SSCDKHCCHN FAYNKHIHKF WLPVILISID FEAVE 

« Hide

References

[1]"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H. expand/collapse author list , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC010907 Genomic DNA. No translation available.
AC019172 Genomic DNA. No translation available.
UniGeneHs.304233.
Hs.631689.

3D structure databases

ProteinModelPortalA8MYV0.
SMRA8MYV0. Positions 15-97, 138-216.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteA8MYV0.

Proteomic databases

PaxDbA8MYV0.
PRIDEA8MYV0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000399143; ENSP00000382097; ENSG00000214866.

Organism-specific databases

GeneCardsGC02P003750.
HGNCHGNC:32696. DCDC2C.
HPAHPA045848.
neXtProtNX_A8MYV0.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG116978.
InParanoidA8MYV0.
PhylomeDBA8MYV0.

Gene expression databases

BgeeA8MYV0.
GenevestigatorA8MYV0.

Family and domain databases

Gene3D3.10.20.230. 2 hits.
InterProIPR003533. Doublecortin_dom.
[Graphical view]
PfamPF03607. DCX. 2 hits.
[Graphical view]
SMARTSM00537. DCX. 2 hits.
[Graphical view]
PROSITEPS50309. DC. 2 hits.
[Graphical view]
ProtoNetSearch...

Other

PROA8MYV0.

Entry information

Entry nameDCD2C_HUMAN
AccessionPrimary (citable) accession number: A8MYV0
Entry history
Integrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: February 8, 2011
Last modified: April 16, 2014
This is version 41 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 2

Human chromosome 2: entries, gene names and cross-references to MIM