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Protein

Doublecortin domain-containing protein 2C

Gene

DCDC2C

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Doublecortin domain-containing protein 2C
Gene namesi
Name:DCDC2C
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000214866.7
HGNCiHGNC:32696 DCDC2C
neXtProtiNX_A8MYV0

Subcellular locationi

Keywords - Cellular componenti

Cell projection, Cilium, Cytoplasm, Flagellum

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003444491 – 355Doublecortin domain-containing protein 2CAdd BLAST355

Proteomic databases

PaxDbiA8MYV0
PRIDEiA8MYV0

PTM databases

iPTMnetiA8MYV0
PhosphoSitePlusiA8MYV0

Expressioni

Tissue specificityi

Expressed in testis and spermatozoa (at protein level).1 Publication

Gene expression databases

BgeeiENSG00000214866

Organism-specific databases

HPAiHPA045848

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000403984

Structurei

3D structure databases

ProteinModelPortaliA8MYV0
SMRiA8MYV0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 98Doublecortin 1PROSITE-ProRule annotationAdd BLAST83
Domaini136 – 217Doublecortin 2PROSITE-ProRule annotationAdd BLAST82

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG3757 Eukaryota
ENOG410ZE6Q LUCA
InParanoidiA8MYV0
OrthoDBiEOG091G13U4
PhylomeDBiA8MYV0

Family and domain databases

CDDicd01617 DCX, 1 hit
Gene3Di3.10.20.230, 2 hits
InterProiView protein in InterPro
IPR003533 Doublecortin_dom
IPR036572 Doublecortin_dom_sf
PfamiView protein in Pfam
PF03607 DCX, 2 hits
SMARTiView protein in SMART
SM00537 DCX, 2 hits
SUPFAMiSSF89837 SSF89837, 2 hits
PROSITEiView protein in PROSITE
PS50309 DC, 2 hits

Sequencei

Sequence statusi: Complete.

A8MYV0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGTRGPSAPV DTTPAKTIVV YRNGDPFYVG KKFVLSRRRA ATFEALLEQL
60 70 80 90 100
TEQVDVPFGV RRLFTPTRGH RVLGLDALQA GGKYVAAGRE RFKELDYIHI
110 120 130 140 150
VPRKPAKIRK LKEIKPVVHC DINVPSKWQT YHRISRHINV FTNGRLFIPP
160 170 180 190 200
AKIIIPKFSL SDWDIVLATI GEKVFPLGGV RKLFTMNGHL LGDSKDLQDN
210 220 230 240 250
HFYVAVGLET FKYFPYWKSP RVPSEVQQRY ANVEKNSQRK KKVDSKGKEP
260 270 280 290 300
CKYDGIPPKT QDSVYYAKEE KKKTLAEPLV QRGAEGDVYK APTPSKETQG
310 320 330 340 350
ALDVKEEHNV QLEVPVDQAE SSCDKHCCHN FAYNKHIHKF WLPVILISID

FEAVE
Length:355
Mass (Da):40,425
Last modified:February 8, 2011 - v3
Checksum:iAC2BD3EDED18C794
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010907 Genomic DNA No translation available.
AC019172 Genomic DNA No translation available.
UniGeneiHs.304233
Hs.631689

Genome annotation databases

EnsembliENST00000399143; ENSP00000382097; ENSG00000214866
UCSCiuc032nde.2 human

Similar proteinsi

Entry informationi

Entry nameiDCD2C_HUMAN
AccessioniPrimary (citable) accession number: A8MYV0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: February 8, 2011
Last modified: April 25, 2018
This is version 63 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health