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Protein

Tetratricopeptide repeat protein 34

Gene

TTC34

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Tetratricopeptide repeat protein 34
Short name:
TPR repeat protein 34
Gene namesi
Name:TTC34
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000215912.11
HGNCiHGNC:34297 TTC34
neXtProtiNX_A8MYJ7

Pathology & Biotechi

Organism-specific databases

DisGeNETi100287898
OpenTargetsiENSG00000215912
PharmGKBiPA162407211

Polymorphism and mutation databases

BioMutaiTTC34

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003412781 – 566Tetratricopeptide repeat protein 34Add BLAST566

Proteomic databases

PaxDbiA8MYJ7
PRIDEiA8MYJ7

PTM databases

PhosphoSitePlusiA8MYJ7

Expressioni

Gene expression databases

BgeeiENSG00000215912
CleanExiHS_TTC34
ExpressionAtlasiA8MYJ7 baseline and differential

Organism-specific databases

HPAiHPA066832

Interactioni

Protein-protein interaction databases

BioGridi939557, 1 interactor
STRINGi9606.ENSP00000383873

Structurei

3D structure databases

ProteinModelPortaliA8MYJ7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati50 – 83TPR 1Add BLAST34
Repeati178 – 211TPR 2Add BLAST34
Repeati212 – 245TPR 3Add BLAST34
Repeati306 – 339TPR 4Add BLAST34
Repeati341 – 373TPR 5Add BLAST33
Repeati424 – 457TPR 6Add BLAST34
Repeati464 – 497TPR 7Add BLAST34
Repeati512 – 545TPR 8Add BLAST34

Keywords - Domaini

Repeat, TPR repeat

Phylogenomic databases

eggNOGiENOG410IE0N Eukaryota
ENOG410ZKC0 LUCA
GeneTreeiENSGT00390000003047
HOGENOMiHOG000154706
HOVERGENiHBG108612
InParanoidiA8MYJ7
OrthoDBiEOG091G01H4
PhylomeDBiA8MYJ7
TreeFamiTF332803

Family and domain databases

Gene3Di1.25.40.10, 2 hits
InterProiView protein in InterPro
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
SMARTiView protein in SMART
SM00028 TPR, 7 hits
SUPFAMiSSF48452 SSF48452, 3 hits
PROSITEiView protein in PROSITE
PS50005 TPR, 6 hits
PS50293 TPR_REGION, 4 hits

Sequencei

Sequence statusi: Complete.

A8MYJ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLQRSPRAGP SRAQGRREAA ETGGPTTQEG VACGVHQLAT LLMELDSEDE
60 70 80 90 100
ASRLLAADAL YRLGRLEETH KALLVALSRR PQAAPVLARL ALLQLRRGFF
110 120 130 140 150
YDANQLVKKL VQSGDTACLQ PTLDVFCHED RQLLQGHCHA RALAILRARP
160 170 180 190 200
GGADGRVHTK EAIAYLSLAI FAAGSQASES LLARARCYGF LGQKKTAMFD
210 220 230 240 250
FNTVLRAEPG NVQALCGRAL VHLALDQLQE AVDDIVSALK LGPGTVVPEL
260 270 280 290 300
RSLKPEAQAL ITQGLYSHCR ALLSQLPDTG APLEDKDTQG LLAVGEALIK
310 320 330 340 350
IDSGQPHWHL LLADILMAQG SYEEAGTHLE KALHRAPTSE AARARLGLLQ
360 370 380 390 400
LKKGDVPGAA RDLQSLAEVD APDLSCLLHL LEASERQSLA QAAAQEAGTL
410 420 430 440 450
LDAGQPRQAL GYCSLSVLAS GSSACHLRLR ATCLAELQEF GRALRDLDHV
460 470 480 490 500
LQEALGDGDL PRRAEDFCRQ GRLLLSLGDE AAAAGAFAQA LKLAPSLAQN
510 520 530 540 550
SLCRQPGRAP TARMFLLRGQ CCLEEQRHAE AWTAVESGLL VDPDHRGLKR
560
LKARIRREAS SGCWLQ
Length:566
Mass (Da):60,903
Last modified:June 10, 2008 - v2
Checksum:i6668E05E87DC3E73
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL592464 Genomic DNA No translation available.
AL831784 Genomic DNA No translation available.
DN831537 mRNA No translation available.
DN831538 mRNA No translation available.
DY655627 mRNA No translation available.
CCDSiCCDS55565.1
RefSeqiNP_001229601.1, NM_001242672.1
XP_016855479.1, XM_016999990.1
UniGeneiHs.632363

Genome annotation databases

EnsembliENST00000611612; ENSP00000483029; ENSG00000275571
ENST00000637179; ENSP00000490537; ENSG00000215912
GeneIDi100287898
KEGGihsa:100287898
UCSCiuc021oey.2 human

Similar proteinsi

Entry informationi

Entry nameiTTC34_HUMAN
AccessioniPrimary (citable) accession number: A8MYJ7
Secondary accession number(s): A8MXL8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: June 10, 2008
Last modified: May 23, 2018
This is version 93 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM

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