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A8MYE6 (A8MYE6_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length712 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Membrane; Single-pass type I membrane protein By similarity RuleBase RU000633.

Sequence similarities

Belongs to the integrin beta chain family. RuleBase RU000633

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000380952

Ontologies

Sequences

Sequence LengthMass (Da)Tools
A8MYE6 [UniParc].

Last modified December 4, 2007. Version 1.
Checksum: 7792B69E2571C676

FASTA71278,345
        10         20         30         40         50         60 
MLGLRPPLLA LVGLLSLGCV LSQECTKFKV SSCRECIESG PGCTWCQKLN FTGPGDPDSI 

        70         80         90        100        110        120 
RCDTRPQLLM RGCAADDIMD PTSLAETQED HNGGQKQLSP QKVTLYLRPG FGSFVDKTVL 

       130        140        150        160        170        180 
PFVNTHPDKL RNPCPNKEKE CQPPFAFRHV LKLTNNSNQF QTEVGKQLIS GNLDAPEGGL 

       190        200        210        220        230        240 
DAMMQVAACP EEIGWRNVTR LLVFATDDGF HFAGDGKLGA ILTPNDGRCH LEDNLYKRSN 

       250        260        270        280        290        300 
EFDYPSVGQL AHKLAENNIQ PIFAVTSRMV KTYEKLTEII PKSAVGELSE DSSNVVQLIK 

       310        320        330        340        350        360 
NAYNKLSSRV FLDHNALPDT LKVTYDSFCS NGVTHRNQPR GDCDGVQINV PITFQVKVTA 

       370        380        390        400        410        420 
TECIQEQSFV IRALGFTDIV TVQVLPQCEC RCRDQSRDRS LCHGKGFLEC GICRCDTGYI 

       430        440        450        460        470        480 
GKNCECQTQG RSSQELEGSC RKDNNSIICS GLGDCVCGQC LCHTSDVPGK LIYGQYCECD 

       490        500        510        520        530        540 
TINCERYNGQ VCGGPGRGLC FCGKCRCHPG FEGSACQCER TTEGCLNPRR VECSGRGRCR 

       550        560        570        580        590        600 
CNVCECHSGY QLPLCQECPG CPSPCGKYIS CAECLKFEKG PFGKNCSAAC PGLQLSNNPV 

       610        620        630        640        650        660 
KGRTCKERDS EGCWVAYTLE QQDGMDRYLI YVDESRECVA GPNIAAIVGG TVAGIVLIGI 

       670        680        690        700        710 
LLLVIWKALI HLSDLREYRR FEKEKLKSQW NNDNPLFKSA TTTVMNPKFA ES 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL773603 Genomic DNA. No translation available.
AL844907 Genomic DNA. No translation available.
AL844908 Genomic DNA. No translation available.
UniGeneHs.375957.

3D structure databases

ProteinModelPortalA8MYE6.
SMRA8MYE6. Positions 23-639, 641-706.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEA8MYE6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000397854; ENSP00000380952; ENSG00000160255.
KEGGhsa:3689.
UCSCuc010gpw.2. human.

Organism-specific databases

CTD3689.
HGNCHGNC:6155. ITGB2.
GenAtlasSearch...

Phylogenomic databases

HOGENOMHOG000252936.
HOVERGENHBG006190.
KOK06464.

Enzyme and pathway databases

SignaLinkA8MYE6.

Gene expression databases

ArrayExpressA8MYE6.
BgeeA8MYE6.

Family and domain databases

Gene3D3.40.50.410. 1 hit.
InterProIPR015812. Integrin_bsu.
IPR015439. Integrin_bsu-2.
IPR014836. Integrin_bsu_cyt_dom.
IPR002369. Integrin_bsu_N.
IPR012896. Integrin_bsu_tail.
IPR016201. Plexin-like_fold.
IPR002035. VWF_A.
[Graphical view]
PANTHERPTHR10082. PTHR10082. 1 hit.
PTHR10082:SF15. PTHR10082:SF15. 1 hit.
PfamPF08725. Integrin_b_cyt. 1 hit.
PF07965. Integrin_B_tail. 1 hit.
PF00362. Integrin_beta. 2 hits.
[Graphical view]
PIRSFPIRSF002512. Integrin_B. 1 hit.
PRINTSPR01186. INTEGRINB.
SMARTSM00187. INB. 1 hit.
SM00423. PSI. 1 hit.
[Graphical view]
SUPFAMSSF103575. SSF103575. 1 hit.
SSF53300. SSF53300. 1 hit.
SSF69687. SSF69687. 1 hit.
PROSITEPS00243. INTEGRIN_BETA. 3 hits.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSITGB2. human.
GenomeRNAi3689.
NextBio35465048.

Entry information

Entry nameA8MYE6_HUMAN
AccessionPrimary (citable) accession number: A8MYE6
Entry history
Integrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: April 16, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.