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A8MXT2

- MAGBH_HUMAN

UniProt

A8MXT2 - MAGBH_HUMAN

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Protein

Melanoma-associated antigen B17

Gene
MAGEB17
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Protein predictedi

Names & Taxonomyi

Protein namesi
Recommended name:
Melanoma-associated antigen B17
Gene namesi
Name:MAGEB17
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome X

Organism-specific databases

HGNCiHGNC:17418. MAGEB17.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134872991.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 336336Melanoma-associated antigen B17PRO_0000332218Add
BLAST

Proteomic databases

PaxDbiA8MXT2.
PRIDEiA8MXT2.

PTM databases

PhosphoSiteiA8MXT2.

Expressioni

Gene expression databases

BgeeiA8MXT2.
GenevestigatoriA8MXT2.

Organism-specific databases

HPAiHPA003756.

Structurei

3D structure databases

ProteinModelPortaliA8MXT2.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini109 – 336228MAGEAdd
BLAST

Sequence similaritiesi

Contains 1 MAGE domain.

Phylogenomic databases

eggNOGiNOG266245.
HOGENOMiHOG000231161.
HOVERGENiHBG006315.
InParanoidiA8MXT2.
OrthoDBiEOG75F4GM.
PhylomeDBiA8MXT2.
TreeFamiTF328505.

Family and domain databases

InterProiIPR002190. MAGE.
IPR021072. Melanoma_ass_antigen_N.
[Graphical view]
PANTHERiPTHR11736. PTHR11736. 1 hit.
PfamiPF01454. MAGE. 1 hit.
PF12440. MAGE_N. 1 hit.
[Graphical view]
PROSITEiPS50838. MAGE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8MXT2-1 [UniParc]FASTAAdd to Basket

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MPRGQASKRR AREKRRQARG EDQCLGGAQA TAAEKEKLPS SSSPACQSPP    50
QSFPNAGIPQ ESQRASYPSS PASAVSLTSS DEGAKGQKGE SPNSFHGPSS 100
SESTGRDLLN TKTGELVQFL LNKYIRKEPI TREAMLKVIN RKYKQHFPEI 150
LRRSTENVEV VFGLYLKEMD PSRQSYVLVG KLDFPNQGSL SDGGGFPLSG 200
LLMVLLSTIF MHGNRATEEE MWECLNALGM YKGRKHFIYG EPQELVTKDL 250
VREGYLEYQQ VPSSDPPRYE FLWGPRARAE TSKMKVLEFV AKLNDTVAST 300
YKSRYEEALR EEEEQARARA VARDSARARA SRSFQP 336
Length:336
Mass (Da):37,578
Last modified:May 14, 2014 - v3
Checksum:iD6CA349109F6BEE4
GO

Sequence cautioni

The sequence EAW98911.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC078993 Genomic DNA. No translation available.
CH471074 Genomic DNA. Translation: EAW98911.1. Sequence problems.
CCDSiCCDS59524.1.
RefSeqiNP_001264236.1. NM_001277307.1.
UniGeneiHs.632792.

Genome annotation databases

EnsembliENST00000329538; ENSP00000328274; ENSG00000182798.
ENST00000400003; ENSP00000382883; ENSG00000182798.
ENST00000400004; ENSP00000382884; ENSG00000182798.
GeneIDi645864.
UCSCiuc031tgu.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC078993 Genomic DNA. No translation available.
CH471074 Genomic DNA. Translation: EAW98911.1 . Sequence problems.
CCDSi CCDS59524.1.
RefSeqi NP_001264236.1. NM_001277307.1.
UniGenei Hs.632792.

3D structure databases

ProteinModelPortali A8MXT2.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei A8MXT2.

Proteomic databases

PaxDbi A8MXT2.
PRIDEi A8MXT2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000329538 ; ENSP00000328274 ; ENSG00000182798 .
ENST00000400003 ; ENSP00000382883 ; ENSG00000182798 .
ENST00000400004 ; ENSP00000382884 ; ENSG00000182798 .
GeneIDi 645864.
UCSCi uc031tgu.1. human.

Organism-specific databases

GeneCardsi GC0XP016183.
HGNCi HGNC:17418. MAGEB17.
HPAi HPA003756.
MIMi 300763. gene.
neXtProti NX_A8MXT2.
PharmGKBi PA134872991.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG266245.
HOGENOMi HOG000231161.
HOVERGENi HBG006315.
InParanoidi A8MXT2.
OrthoDBi EOG75F4GM.
PhylomeDBi A8MXT2.
TreeFami TF328505.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

Bgeei A8MXT2.
Genevestigatori A8MXT2.

Family and domain databases

InterProi IPR002190. MAGE.
IPR021072. Melanoma_ass_antigen_N.
[Graphical view ]
PANTHERi PTHR11736. PTHR11736. 1 hit.
Pfami PF01454. MAGE. 1 hit.
PF12440. MAGE_N. 1 hit.
[Graphical view ]
PROSITEi PS50838. MAGE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The DNA sequence of the human X chromosome."
    Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
    , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
    Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiMAGBH_HUMAN
AccessioniPrimary (citable) accession number: A8MXT2
Secondary accession number(s): A6NE98
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: May 14, 2014
Last modified: September 3, 2014
This is version 53 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Formerly thought to be the product of a pseudogene, although could be a bona fide protein. However, scarce EST evidence confirms only the C-terminal sequence.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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