Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A8MXT2

- MAGBH_HUMAN

UniProt

A8MXT2 - MAGBH_HUMAN

Protein

Melanoma-associated antigen B17

Gene

MAGEB17

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 54 (01 Oct 2014)
      Sequence version 3 (14 May 2014)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Melanoma-associated antigen B17
    Gene namesi
    Name:MAGEB17
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome X

    Organism-specific databases

    HGNCiHGNC:17418. MAGEB17.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134872991.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 336336Melanoma-associated antigen B17PRO_0000332218Add
    BLAST

    Proteomic databases

    PaxDbiA8MXT2.
    PRIDEiA8MXT2.

    PTM databases

    PhosphoSiteiA8MXT2.

    Expressioni

    Gene expression databases

    BgeeiA8MXT2.
    GenevestigatoriA8MXT2.

    Organism-specific databases

    HPAiHPA003756.

    Structurei

    3D structure databases

    ProteinModelPortaliA8MXT2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini109 – 336228MAGEPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 MAGE domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiNOG266245.
    HOGENOMiHOG000231161.
    HOVERGENiHBG006315.
    InParanoidiA8MXT2.
    OrthoDBiEOG75F4GM.
    PhylomeDBiA8MXT2.
    TreeFamiTF328505.

    Family and domain databases

    InterProiIPR002190. MAGE.
    IPR021072. Melanoma_ass_antigen_N.
    [Graphical view]
    PANTHERiPTHR11736. PTHR11736. 1 hit.
    PfamiPF01454. MAGE. 1 hit.
    PF12440. MAGE_N. 1 hit.
    [Graphical view]
    PROSITEiPS50838. MAGE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A8MXT2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPRGQASKRR AREKRRQARG EDQCLGGAQA TAAEKEKLPS SSSPACQSPP    50
    QSFPNAGIPQ ESQRASYPSS PASAVSLTSS DEGAKGQKGE SPNSFHGPSS 100
    SESTGRDLLN TKTGELVQFL LNKYIRKEPI TREAMLKVIN RKYKQHFPEI 150
    LRRSTENVEV VFGLYLKEMD PSRQSYVLVG KLDFPNQGSL SDGGGFPLSG 200
    LLMVLLSTIF MHGNRATEEE MWECLNALGM YKGRKHFIYG EPQELVTKDL 250
    VREGYLEYQQ VPSSDPPRYE FLWGPRARAE TSKMKVLEFV AKLNDTVAST 300
    YKSRYEEALR EEEEQARARA VARDSARARA SRSFQP 336
    Length:336
    Mass (Da):37,578
    Last modified:May 14, 2014 - v3
    Checksum:iD6CA349109F6BEE4
    GO

    Sequence cautioni

    The sequence EAW98911.1 differs from that shown. Reason: Erroneous gene model prediction.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC078993 Genomic DNA. No translation available.
    CH471074 Genomic DNA. Translation: EAW98911.1. Sequence problems.
    CCDSiCCDS59524.1.
    RefSeqiNP_001264236.1. NM_001277307.1.
    UniGeneiHs.632792.

    Genome annotation databases

    EnsembliENST00000400003; ENSP00000382883; ENSG00000182798.
    ENST00000400004; ENSP00000382884; ENSG00000182798.
    GeneIDi645864.
    UCSCiuc031tgu.1. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC078993 Genomic DNA. No translation available.
    CH471074 Genomic DNA. Translation: EAW98911.1 . Sequence problems.
    CCDSi CCDS59524.1.
    RefSeqi NP_001264236.1. NM_001277307.1.
    UniGenei Hs.632792.

    3D structure databases

    ProteinModelPortali A8MXT2.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei A8MXT2.

    Proteomic databases

    PaxDbi A8MXT2.
    PRIDEi A8MXT2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000400003 ; ENSP00000382883 ; ENSG00000182798 .
    ENST00000400004 ; ENSP00000382884 ; ENSG00000182798 .
    GeneIDi 645864.
    UCSCi uc031tgu.1. human.

    Organism-specific databases

    CTDi 645864.
    GeneCardsi GC0XP016183.
    HGNCi HGNC:17418. MAGEB17.
    HPAi HPA003756.
    MIMi 300763. gene.
    neXtProti NX_A8MXT2.
    PharmGKBi PA134872991.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG266245.
    HOGENOMi HOG000231161.
    HOVERGENi HBG006315.
    InParanoidi A8MXT2.
    OrthoDBi EOG75F4GM.
    PhylomeDBi A8MXT2.
    TreeFami TF328505.

    Miscellaneous databases

    SOURCEi Search...

    Gene expression databases

    Bgeei A8MXT2.
    Genevestigatori A8MXT2.

    Family and domain databases

    InterProi IPR002190. MAGE.
    IPR021072. Melanoma_ass_antigen_N.
    [Graphical view ]
    PANTHERi PTHR11736. PTHR11736. 1 hit.
    Pfami PF01454. MAGE. 1 hit.
    PF12440. MAGE_N. 1 hit.
    [Graphical view ]
    PROSITEi PS50838. MAGE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence of the human X chromosome."
      Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
      , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
      Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiMAGBH_HUMAN
    AccessioniPrimary (citable) accession number: A8MXT2
    Secondary accession number(s): A6NE98
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 29, 2008
    Last sequence update: May 14, 2014
    Last modified: October 1, 2014
    This is version 54 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    Formerly thought to be the product of a pseudogene, although could be a bona fide protein. However, scarce EST evidence confirms only the C-terminal sequence.Curated

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome X
      Human chromosome X: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3