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Protein
Submitted name:

MAPK10 protein

Gene

MAPK10

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
MAPK10 proteinImported
Submitted name:
Mitogen-activated protein kinase 10Imported
Gene namesi
Name:MAPK10Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

HGNCiHGNC:6872. MAPK10.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000109339.

Expressioni

Gene expression databases

BgeeiENSG00000109339.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000352157.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 214Protein kinaseInterPro annotationAdd BLAST214

Phylogenomic databases

eggNOGiKOG0665. Eukaryota.
ENOG410XSHI. LUCA.
GeneTreeiENSGT00550000074271.
HOGENOMiHOG000233024.
HOVERGENiHBG014652.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR008351. MAPK_JNK.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSiPR01772. JNKMAPKINASE.
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8MWW6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELMDANLCQ VIQMELDHER MSYLLYQMLC GIKHLHSAGI IHRDLKPSNI
60 70 80 90 100
VVKSDCTLKI LDFGLARTAG TSFMMTPYVV TRYYRAPEVI LGMGYKENVD
110 120 130 140 150
IWSVGCIMGE MVRHKILFPG RDYIDQWNKV IEQLGTPCPE FMKKLQPTVR
160 170 180 190 200
NYVENRPKYA GLTFPKLFPD SLFPADSEHN KLKASQARDL LSKMLVIDPA
210 220 230 240 250
KRISVDDALQ HPYINVWYDP AEVEAPPPQI YDKQLDEREH TIEEWKELIY
260 270 280 290 300
KEVMNSEEKT KNGVVKGQPS PSGAAVNSSE SLPPSSSVND ISSMSTDQTL
310
ASDTDSSLEA SAGPLGCCR
Length:319
Mass (Da):35,964
Last modified:November 3, 2009 - v2
Checksum:iB576EB015F28C1D2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC096953 Genomic DNA. No translation available.
AC104059 Genomic DNA. No translation available.
AC104827 Genomic DNA. No translation available.
AC108054 Genomic DNA. No translation available.
AC110076 Genomic DNA. No translation available.
BC065516 mRNA. Translation: AAH65516.1.
RefSeqiXP_016863936.1. XM_017008447.1.
XP_016863937.1. XM_017008448.1.
UniGeneiHs.125503.
Hs.13438.

Genome annotation databases

EnsembliENST00000395157; ENSP00000378586; ENSG00000109339.
GeneIDi5602.
UCSCiuc003hpo.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC096953 Genomic DNA. No translation available.
AC104059 Genomic DNA. No translation available.
AC104827 Genomic DNA. No translation available.
AC108054 Genomic DNA. No translation available.
AC110076 Genomic DNA. No translation available.
BC065516 mRNA. Translation: AAH65516.1.
RefSeqiXP_016863936.1. XM_017008447.1.
XP_016863937.1. XM_017008448.1.
UniGeneiHs.125503.
Hs.13438.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000352157.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000395157; ENSP00000378586; ENSG00000109339.
GeneIDi5602.
UCSCiuc003hpo.4. human.

Organism-specific databases

CTDi5602.
HGNCiHGNC:6872. MAPK10.
OpenTargetsiENSG00000109339.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0665. Eukaryota.
ENOG410XSHI. LUCA.
GeneTreeiENSGT00550000074271.
HOGENOMiHOG000233024.
HOVERGENiHBG014652.

Miscellaneous databases

ChiTaRSiMAPK10. human.
GenomeRNAii5602.

Gene expression databases

BgeeiENSG00000109339.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR008351. MAPK_JNK.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSiPR01772. JNKMAPKINASE.
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA8MWW6_HUMAN
AccessioniPrimary (citable) accession number: A8MWW6
Entry historyi
Integrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: November 3, 2009
Last modified: November 30, 2016
This is version 83 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.