ID   SM34A_HUMAN             Reviewed;         139 AA.
AC   A8MWV9;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   04-DEC-2007, sequence version 1.
DT   24-JAN-2024, entry version 100.
DE   RecName: Full=Small integral membrane protein 34 {ECO:0000305};
GN   Name=SMIM34 {ECO:0000312|HGNC:HGNC:39601}; Synonyms=SMIM34A;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=10830953; DOI=10.1038/35012518;
RA   Hattori M., Fujiyama A., Taylor T.D., Watanabe H., Yada T., Park H.-S.,
RA   Toyoda A., Ishii K., Totoki Y., Choi D.-K., Groner Y., Soeda E., Ohki M.,
RA   Takagi T., Sakaki Y., Taudien S., Blechschmidt K., Polley A., Menzel U.,
RA   Delabar J., Kumpf K., Lehmann R., Patterson D., Reichwald K., Rump A.,
RA   Schillhabel M., Schudy A., Zimmermann W., Rosenthal A., Kudoh J.,
RA   Shibuya K., Kawasaki K., Asakawa S., Shintani A., Sasaki T., Nagamine K.,
RA   Mitsuyama S., Antonarakis S.E., Minoshima S., Shimizu N., Nordsiek G.,
RA   Hornischer K., Brandt P., Scharfe M., Schoen O., Desario A., Reichelt J.,
RA   Kauer G., Bloecker H., Ramser J., Beck A., Klages S., Hennig S.,
RA   Riesselmann L., Dagand E., Wehrmeyer S., Borzym K., Gardiner K.,
RA   Nizetic D., Francis F., Lehrach H., Reinhardt R., Yaspo M.-L.;
RT   "The DNA sequence of human chromosome 21.";
RL   Nature 405:311-319(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AP000322; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC049386; -; NOT_ANNOTATED_CDS; mRNA.
DR   CCDS; CCDS93093.1; -.
DR   RefSeq; XP_006724011.1; XM_006723948.3.
DR   RefSeq; XP_011507198.1; XM_011508896.2.
DR   RefSeq; XP_016884011.1; XM_017028522.1.
DR   AlphaFoldDB; A8MWV9; -.
DR   SMR; A8MWV9; -.
DR   STRING; 9606.ENSP00000397039; -.
DR   BioMuta; -; -.
DR   PaxDb; 9606-ENSP00000397039; -.
DR   PeptideAtlas; A8MWV9; -.
DR   Antibodypedia; 49026; 3 antibodies from 3 providers.
DR   Ensembl; ENST00000450895.2; ENSP00000397039.2; ENSG00000243627.5.
DR   MANE-Select; ENST00000450895.2; ENSP00000397039.2; NM_001367348.2; NP_001354277.1.
DR   UCSC; uc002yty.3; human.
DR   AGR; HGNC:39601; -.
DR   GeneCards; SMIM34; -.
DR   HGNC; HGNC:39601; SMIM34.
DR   HPA; ENSG00000243627; Tissue enhanced (kidney).
DR   neXtProt; NX_A8MWV9; -.
DR   VEuPathDB; HostDB:ENSG00000243627; -.
DR   eggNOG; ENOG502TABH; Eukaryota.
DR   GeneTree; ENSGT00490000044099; -.
DR   HOGENOM; CLU_1844479_0_0_1; -.
DR   InParanoid; A8MWV9; -.
DR   OMA; QSKVAKC; -.
DR   OrthoDB; 5264109at2759; -.
DR   PhylomeDB; A8MWV9; -.
DR   BioGRID-ORCS; 388820; 0 hits in 4 CRISPR screens.
DR   Pharos; A8MWV9; Tdark.
DR   PRO; PR:A8MWV9; -.
DR   Proteomes; UP000005640; Chromosome 21.
DR   RNAct; A8MWV9; Protein.
DR   Bgee; ENSG00000243627; Expressed in olfactory segment of nasal mucosa and 79 other cell types or tissues.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..139
FT                   /note="Small integral membrane protein 34"
FT                   /id="PRO_0000348245"
FT   TRANSMEM        46..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   139 AA;  15007 MW;  30E5C201208C132A CRC64;
     MEWAKWTPHE ASNQTQASTL LGLLLGDHTE GRNDTNSTRA LKVPDGTSAA WYILTIIGIY
     AVIFVFRLAS NILRKNDKSL EDVYYSNLTS ELKMTGLQGK VAKCSTLSIS NRAVLQPCQA
     HLGAKGGSSG PQTATPETP
//