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A8MWE9

- EFCB8_HUMAN

UniProt

A8MWE9 - EFCB8_HUMAN

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Protein

EF-hand calcium-binding domain-containing protein 8

Gene
EFCAB8
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
EF-hand calcium-binding domain-containing protein 8
Gene namesi
Name:EFCAB8
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 20

Organism-specific databases

HGNCiHGNC:34532. EFCAB8.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 144144EF-hand calcium-binding domain-containing protein 8PRO_0000340678Add
BLAST

Proteomic databases

PaxDbiA8MWE9.
PRIDEiA8MWE9.

PTM databases

PhosphoSiteiA8MWE9.

Expressioni

Gene expression databases

BgeeiA8MWE9.
GenevestigatoriA8MWE9.

Organism-specific databases

HPAiCAB034246.
HPA042751.

Structurei

3D structure databases

ProteinModelPortaliA8MWE9.
SMRiA8MWE9. Positions 50-113.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini52 – 8635EF-hand 1Add
BLAST
Domaini87 – 12236EF-hand 2Add
BLAST

Sequence similaritiesi

Contains 2 EF-hand domains.

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiCOG2319.
HOVERGENiHBG107837.
InParanoidiA8MWE9.
PhylomeDBiA8MWE9.
TreeFamiTF353054.

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
InterProiIPR011992. EF-hand-dom_pair.
IPR002048. EF_hand_dom.
[Graphical view]
PROSITEiPS50222. EF_HAND_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8MWE9-1 [UniParc]FASTAAdd to Basket

« Hide

MSSEDLAEIP QLQKLSIPHG FQNKEAASSP TPSITLSQVP DLQPGSQLFT    50
EIHLAKIEKM FEEDINSTGA LGMDAFIKAM KKVLSSVSDE MLKELFLKVD 100
SDCEGFVTWQ KYVDYMMREF QGKEDMRKSQ YRLHFYLPMT VVPL 144
Length:144
Mass (Da):16,428
Last modified:June 10, 2008 - v2
Checksum:iBA081DF55B37B0BB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL390298 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000400522; ENSP00000383366; ENSG00000215529.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL390298 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali A8MWE9.
SMRi A8MWE9. Positions 50-113.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei A8MWE9.

Proteomic databases

PaxDbi A8MWE9.
PRIDEi A8MWE9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000400522 ; ENSP00000383366 ; ENSG00000215529 .

Organism-specific databases

GeneCardsi GC20P031446.
HGNCi HGNC:34532. EFCAB8.
HPAi CAB034246.
HPA042751.
neXtProti NX_A8MWE9.
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG2319.
HOVERGENi HBG107837.
InParanoidi A8MWE9.
PhylomeDBi A8MWE9.
TreeFami TF353054.

Gene expression databases

Bgeei A8MWE9.
Genevestigatori A8MWE9.

Family and domain databases

Gene3Di 1.10.238.10. 1 hit.
InterProi IPR011992. EF-hand-dom_pair.
IPR002048. EF_hand_dom.
[Graphical view ]
PROSITEi PS50222. EF_HAND_2. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The DNA sequence and comparative analysis of human chromosome 20."
    Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E.
    , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
    Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiEFCB8_HUMAN
AccessioniPrimary (citable) accession number: A8MWE9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: June 10, 2008
Last modified: June 11, 2014
This is version 51 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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