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A8MWD9 (RUXGL_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative small nuclear ribonucleoprotein G-like protein 15
Gene names
Name:SNRPGP15
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length76 AA.
Sequence statusComplete.
Protein existenceUncertain

General annotation (Comments)

Function

Associated with snRNP U1, U2, U4/U6 and U5 By similarity.

Subcellular location

Nucleus By similarity.

Sequence similarities

Belongs to the snRNP Sm proteins family.

Caution

Could be the product of a pseudogene.

Ontologies

Keywords
   Biological processmRNA processing
mRNA splicing
   Cellular componentNucleus
Spliceosome
   LigandRNA-binding
   Molecular functionRibonucleoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processRNA splicing

Inferred from electronic annotation. Source: UniProtKB-KW

mRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentspliceosomal complex

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 7676Putative small nuclear ribonucleoprotein G-like protein 15
PRO_0000348240

Experimental info

Sequence conflict501T → I in CK005235. Ref.2
Sequence conflict681I → F in CK005235. Ref.2
Sequence conflict731L → K in CK005235. Ref.2

Sequences

Sequence LengthMass (Da)Tools
A8MWD9 [UniParc].

Last modified September 2, 2008. Version 2.
Checksum: BF93159251E1E44A

FASTA768,544
        10         20         30         40         50         60 
MSKAHPPELK KFTDKKFSLK LNGGRHVQGI LRGFDPFMNL VIDECVEMAT SGQQKNIGMV 

        70 
EIRGNSIIML EALERV 

« Hide

References

[1]"The DNA sequence and biology of human chromosome 19."
Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V. expand/collapse author list , Caoile C., Chan Y.M., Christensen M., Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., Rubin E.M., Lucas S.M.
Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Frontal cortex.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC012318 Genomic DNA. No translation available.
CK005235 mRNA. No translation available.
UniGeneHs.631639.

3D structure databases

ProteinModelPortalA8MWD9.
SMRA8MWD9. Positions 3-76.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

MaxQBA8MWD9.
PaxDbA8MWD9.
PRIDEA8MWD9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

HGNCHGNC:49371. SNRPGP15.
neXtProtNX_A8MWD9.
GenAtlasSearch...

Phylogenomic databases

eggNOGCOG1958.
HOVERGENHBG000513.
InParanoidA8MWD9.
PhylomeDBA8MWD9.

Gene expression databases

BgeeA8MWD9.
GenevestigatorA8MWD9.

Family and domain databases

InterProIPR010920. LSM_dom.
IPR001163. Ribonucl_LSM.
IPR006649. Ribonucl_LSM_euk/arc.
[Graphical view]
PfamPF01423. LSM. 1 hit.
[Graphical view]
SMARTSM00651. Sm. 1 hit.
[Graphical view]
SUPFAMSSF50182. SSF50182. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRUXGL_HUMAN
AccessionPrimary (citable) accession number: A8MWD9
Entry history
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: September 2, 2008
Last modified: July 9, 2014
This is version 50 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 19

Human chromosome 19: entries, gene names and cross-references to MIM