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A8MWD9

- RUXGL_HUMAN

UniProt

A8MWD9 - RUXGL_HUMAN

Protein

Putative small nuclear ribonucleoprotein G-like protein 15

Gene

SNRPGP15

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Protein uncertaini
  1. Functioni

    Associated with snRNP U1, U2, U4/U6 and U5.By similarity

    GO - Molecular functioni

    1. RNA binding Source: UniProtKB-KW

    GO - Biological processi

    1. mRNA processing Source: UniProtKB-KW
    2. RNA splicing Source: UniProtKB-KW

    Keywords - Molecular functioni

    Ribonucleoprotein

    Keywords - Biological processi

    mRNA processing, mRNA splicing

    Keywords - Ligandi

    RNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative small nuclear ribonucleoprotein G-like protein 15
    Gene namesi
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Unplaced

    Organism-specific databases

    HGNCiHGNC:49371. SNRPGP15.

    Subcellular locationi

    Nucleus By similarity

    GO - Cellular componenti

    1. spliceosomal complex Source: UniProtKB-KW

    Keywords - Cellular componenti

    Nucleus, Spliceosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 7676Putative small nuclear ribonucleoprotein G-like protein 15PRO_0000348240Add
    BLAST

    Proteomic databases

    MaxQBiA8MWD9.
    PaxDbiA8MWD9.
    PRIDEiA8MWD9.

    Expressioni

    Gene expression databases

    BgeeiA8MWD9.
    GenevestigatoriA8MWD9.

    Structurei

    3D structure databases

    ProteinModelPortaliA8MWD9.
    SMRiA8MWD9. Positions 3-76.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the snRNP Sm proteins family.Curated

    Phylogenomic databases

    eggNOGiCOG1958.
    HOVERGENiHBG000513.
    InParanoidiA8MWD9.
    PhylomeDBiA8MWD9.

    Family and domain databases

    InterProiIPR010920. LSM_dom.
    IPR001163. Ribonucl_LSM.
    IPR006649. Ribonucl_LSM_euk/arc.
    [Graphical view]
    PfamiPF01423. LSM. 1 hit.
    [Graphical view]
    SMARTiSM00651. Sm. 1 hit.
    [Graphical view]
    SUPFAMiSSF50182. SSF50182. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A8MWD9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSKAHPPELK KFTDKKFSLK LNGGRHVQGI LRGFDPFMNL VIDECVEMAT   50
    SGQQKNIGMV EIRGNSIIML EALERV 76
    Length:76
    Mass (Da):8,544
    Last modified:September 2, 2008 - v2
    Checksum:iBF93159251E1E44A
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti50 – 501T → I in CK005235. (PubMed:15489334)Curated
    Sequence conflicti68 – 681I → F in CK005235. (PubMed:15489334)Curated
    Sequence conflicti73 – 731L → K in CK005235. (PubMed:15489334)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC012318 Genomic DNA. No translation available.
    CK005235 mRNA. No translation available.
    UniGeneiHs.631639.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC012318 Genomic DNA. No translation available.
    CK005235 mRNA. No translation available.
    UniGenei Hs.631639.

    3D structure databases

    ProteinModelPortali A8MWD9.
    SMRi A8MWD9. Positions 3-76.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    MaxQBi A8MWD9.
    PaxDbi A8MWD9.
    PRIDEi A8MWD9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    HGNCi HGNC:49371. SNRPGP15.
    neXtProti NX_A8MWD9.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG1958.
    HOVERGENi HBG000513.
    InParanoidi A8MWD9.
    PhylomeDBi A8MWD9.

    Gene expression databases

    Bgeei A8MWD9.
    Genevestigatori A8MWD9.

    Family and domain databases

    InterProi IPR010920. LSM_dom.
    IPR001163. Ribonucl_LSM.
    IPR006649. Ribonucl_LSM_euk/arc.
    [Graphical view ]
    Pfami PF01423. LSM. 1 hit.
    [Graphical view ]
    SMARTi SM00651. Sm. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50182. SSF50182. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence and biology of human chromosome 19."
      Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V.
      , Caoile C., Chan Y.M., Christensen M., Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., Rubin E.M., Lucas S.M.
      Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Frontal cortex.

    Entry informationi

    Entry nameiRUXGL_HUMAN
    AccessioniPrimary (citable) accession number: A8MWD9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 2, 2008
    Last sequence update: September 2, 2008
    Last modified: October 1, 2014
    This is version 51 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    Could be the product of a pseudogene.Curated

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 19
      Human chromosome 19: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3