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A8MWD9

- RUXGL_HUMAN

UniProt

A8MWD9 - RUXGL_HUMAN

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Protein

Putative small nuclear ribonucleoprotein G-like protein 15

Gene

SNRPGP15

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Protein uncertaini

Functioni

Associated with snRNP U1, U2, U4/U6 and U5.By similarity

GO - Molecular functioni

  1. RNA binding Source: UniProtKB-KW

GO - Biological processi

  1. mRNA processing Source: UniProtKB-KW
  2. RNA splicing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein

Keywords - Biological processi

mRNA processing, mRNA splicing

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative small nuclear ribonucleoprotein G-like protein 15
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Unplaced

Organism-specific databases

HGNCiHGNC:49371. SNRPGP15.

Subcellular locationi

Nucleus By similarity

GO - Cellular componenti

  1. spliceosomal complex Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Nucleus, Spliceosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 7676Putative small nuclear ribonucleoprotein G-like protein 15PRO_0000348240Add
BLAST

Proteomic databases

MaxQBiA8MWD9.
PaxDbiA8MWD9.
PRIDEiA8MWD9.

Expressioni

Gene expression databases

BgeeiA8MWD9.
GenevestigatoriA8MWD9.

Structurei

3D structure databases

ProteinModelPortaliA8MWD9.
SMRiA8MWD9. Positions 3-76.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the snRNP Sm proteins family.Curated

Phylogenomic databases

eggNOGiCOG1958.
HOVERGENiHBG000513.
PhylomeDBiA8MWD9.

Family and domain databases

InterProiIPR010920. LSM_dom.
IPR001163. Ribonucl_LSM.
IPR006649. Ribonucl_LSM_euk/arc.
[Graphical view]
PfamiPF01423. LSM. 1 hit.
[Graphical view]
SMARTiSM00651. Sm. 1 hit.
[Graphical view]
SUPFAMiSSF50182. SSF50182. 1 hit.

Sequencei

Sequence statusi: Complete.

A8MWD9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSKAHPPELK KFTDKKFSLK LNGGRHVQGI LRGFDPFMNL VIDECVEMAT
60 70
SGQQKNIGMV EIRGNSIIML EALERV
Length:76
Mass (Da):8,544
Last modified:September 2, 2008 - v2
Checksum:iBF93159251E1E44A
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti50 – 501T → I in CK005235. (PubMed:15489334)Curated
Sequence conflicti68 – 681I → F in CK005235. (PubMed:15489334)Curated
Sequence conflicti73 – 731L → K in CK005235. (PubMed:15489334)Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC012318 Genomic DNA. No translation available.
CK005235 mRNA. No translation available.
UniGeneiHs.631639.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC012318 Genomic DNA. No translation available.
CK005235 mRNA. No translation available.
UniGenei Hs.631639.

3D structure databases

ProteinModelPortali A8MWD9.
SMRi A8MWD9. Positions 3-76.
ModBasei Search...
MobiDBi Search...

Proteomic databases

MaxQBi A8MWD9.
PaxDbi A8MWD9.
PRIDEi A8MWD9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

HGNCi HGNC:49371. SNRPGP15.
neXtProti NX_A8MWD9.
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG1958.
HOVERGENi HBG000513.
PhylomeDBi A8MWD9.

Gene expression databases

Bgeei A8MWD9.
Genevestigatori A8MWD9.

Family and domain databases

InterProi IPR010920. LSM_dom.
IPR001163. Ribonucl_LSM.
IPR006649. Ribonucl_LSM_euk/arc.
[Graphical view ]
Pfami PF01423. LSM. 1 hit.
[Graphical view ]
SMARTi SM00651. Sm. 1 hit.
[Graphical view ]
SUPFAMi SSF50182. SSF50182. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The DNA sequence and biology of human chromosome 19."
    Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V.
    , Caoile C., Chan Y.M., Christensen M., Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., Rubin E.M., Lucas S.M.
    Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Frontal cortex.

Entry informationi

Entry nameiRUXGL_HUMAN
AccessioniPrimary (citable) accession number: A8MWD9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: September 2, 2008
Last modified: October 29, 2014
This is version 52 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Could be the product of a pseudogene.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3