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Protein

PHD finger protein 20-like protein 1

Gene

PHF20L1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri681 – 72949PHD-typeAdd
BLAST

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
PHD finger protein 20-like protein 1
Gene namesi
Name:PHF20L1
ORF Names:CGI-72
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

HGNCiHGNC:24280. PHF20L1.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134874888.

Polymorphism and mutation databases

BioMutaiPHF20L1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 10171017PHD finger protein 20-like protein 1PRO_0000336001Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei368 – 3681PhosphoserineBy similarity
Modified residuei433 – 4331PhosphoserineCombined sources
Modified residuei909 – 9091N6-acetyllysineCombined sources

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

EPDiA8MW92.
MaxQBiA8MW92.
PaxDbiA8MW92.
PeptideAtlasiA8MW92.
PRIDEiA8MW92.

PTM databases

iPTMnetiA8MW92.
PhosphoSiteiA8MW92.

Expressioni

Gene expression databases

BgeeiA8MW92.
CleanExiHS_PHF20L1.
ExpressionAtlasiA8MW92. baseline and differential.
GenevisibleiA8MW92. HS.

Organism-specific databases

HPAiHPA025060.
HPA028417.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
HIST1H3DP684312EBI-2560834,EBI-79722
HIST2H4BP628052EBI-2560834,EBI-302023

Protein-protein interaction databases

BioGridi119294. 35 interactions.
IntActiA8MW92. 13 interactions.
MINTiMINT-2830261.
STRINGi9606.ENSP00000378784.

Structurei

Secondary structure

1
1017
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi18 – 225Combined sources
Turni24 – 263Combined sources
Beta strandi28 – 3710Combined sources
Turni38 – 414Combined sources
Beta strandi42 – 509Combined sources
Turni51 – 533Combined sources
Beta strandi54 – 596Combined sources
Turni60 – 623Combined sources
Beta strandi63 – 675Combined sources
Beta strandi92 – 965Combined sources
Beta strandi98 – 11114Combined sources
Beta strandi114 – 1207Combined sources
Beta strandi125 – 1284Combined sources
Helixi130 – 1323Combined sources
Helixi138 – 1403Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2EQMNMR-A1-81[»]
2EQUNMR-A85-177[»]
2JTFNMR-A1-74[»]
ProteinModelPortaliA8MW92.
SMRiA8MW92. Positions 3-81, 85-177, 680-727.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiA8MW92.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini11 – 7161Tudor 1Add
BLAST
Domaini85 – 14157Tudor 2Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi530 – 57950Lys-richAdd
BLAST

Sequence similaritiesi

Contains 1 PHD-type zinc finger.Curated
Contains 2 Tudor domains.Curated

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri681 – 72949PHD-typeAdd
BLAST

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1844. Eukaryota.
ENOG410YHG2. LUCA.
GeneTreeiENSGT00390000006451.
HOVERGENiHBG108227.
InParanoidiA8MW92.
KOiK18402.
OMAiFRNEYPS.
PhylomeDBiA8MW92.
TreeFamiTF106475.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiIPR014002. Agenet_dom_plant.
IPR022255. DUF3776.
IPR002999. Tudor.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF12618. DUF3776. 1 hit.
[Graphical view]
SMARTiSM00743. Agenet. 2 hits.
SM00333. TUDOR. 2 hits.
[Graphical view]
SUPFAMiSSF57903. SSF57903. 1 hit.
PROSITEiPS01359. ZF_PHD_1. 1 hit.
[Graphical view]

Sequences (3)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: A8MW92-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSKKPPNRPG ITFEIGARLE ALDYLQKWYP SRIEKIDYEE GKMLVHFERW
60 70 80 90 100
SHRYDEWIYW DSNRLRPLER PALRKEGLKD EEDFFDFKAG EEVLARWTDC
110 120 130 140 150
RYYPAKIEAI NKEGTFTVQF YDGVIRCLKR MHIKAMPEDA KGQVKSQHPL
160 170 180 190 200
SWCCPIDPAG SCNQSMGSED WIALVKAAAA AAAKNKTGSK PRTSANSNKD
210 220 230 240 250
KDKDERKWFK VPSKKEETST CIATPDVEKK EDLPTSSETF GLHVENVPKM
260 270 280 290 300
VFPQPESTLS NKRKNNQGNS FQAKRARLNK ITGLLASKAV GVDGAEKKED
310 320 330 340 350
YNETAPMLEQ AISPKPQSQK KNEADISSSA NTQKPALLSS TLSSGKARSK
360 370 380 390 400
KCKHESGDSS GCIKPPKSPL SPELIQVEDL TLVSQLSSSV INKTSPPQPV
410 420 430 440 450
NPPRPFKHSE RRRRSQRLAT LPMPDDSVEK VSSPSPATDG KVFSISSQNQ
460 470 480 490 500
QESSVPEVPD VAHLPLEKLG PCLPLDLSRG SEVTAPVASD SSYRNECPRA
510 520 530 540 550
EKEDTQMLPN PSSKAIADGR GAPAAAGISK TEKKVKLEDK SSTAFGKRKE
560 570 580 590 600
KDKERREKRD KDHYRPKQKK KKKKKKKSKQ HDYSDYEDSS LEFLERCSSP
610 620 630 640 650
LTRSSGSSLA SRSMFTEKTT TYQYPRAILS VDLSGENLSD VDFLDDSSTE
660 670 680 690 700
SLLLSGDEYN QDFDSTNFEE SQDEDDALNE IVRCICEMDE ENGFMIQCEE
710 720 730 740 750
CLCWQHSVCM GLLEESIPEQ YICYICRDPP GQRWSAKYRY DKEWLNNGRM
760 770 780 790 800
CGLSFFKENY SHLNAKKIVS THHLLADVYG VTEVLHGLQL KIGILKNKHH
810 820 830 840 850
PDLHLWACSG KRKDQDQIIA GVEKKIAQDT VNREEKKYVQ NHKEPPRLPL
860 870 880 890 900
KMEGTYITSE HSYQKPQSFG QDCKSLADPG SSDDDDVSSL EEEQEFHMRS
910 920 930 940 950
KNSLQYSAKE HGMPEKNPAE GNTVFVYNDK KGTEDPGDSH LQWQLNLLTH
960 970 980 990 1000
IENVQNEVTS RMDLIEKEVD VLESWLDFTG ELEPPDPLAR LPQLKRHIKQ
1010
LLIDMGKVQQ IATLCSV
Length:1,017
Mass (Da):115,010
Last modified:January 11, 2011 - v2
Checksum:i6FF33736EE712836
GO
Isoform 2 (identifier: A8MW92-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     144-169: Missing.
     311-311: A → V
     312-1017: Missing.

Show »
Length:285
Mass (Da):32,825
Checksum:iAFD021E8921F4E0E
GO
Isoform 4 (identifier: A8MW92-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     547-573: KRKEKDKERREKRDKDHYRPKQKKKKK → IRSWDFSALLMKIPSYSPISLSGLPES
     574-1017: Missing.

Show »
Length:573
Mass (Da):63,487
Checksum:i71094E5C08D97D0D
GO

Sequence cautioni

The sequence AAD34067.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence AAP33690.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAB15098.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence EAW92152.1 differs from that shown. Reason: Erroneous gene model prediction. Curated

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei144 – 16926Missing in isoform 2. 2 PublicationsVSP_033781Add
BLAST
Alternative sequencei311 – 3111A → V in isoform 2. 2 PublicationsVSP_033782
Alternative sequencei312 – 1017706Missing in isoform 2. 2 PublicationsVSP_033783Add
BLAST
Alternative sequencei547 – 57327KRKEK…KKKKK → IRSWDFSALLMKIPSYSPIS LSGLPES in isoform 4. 1 PublicationVSP_040407Add
BLAST
Alternative sequencei574 – 1017444Missing in isoform 4. 1 PublicationVSP_040408Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK025268 mRNA. Translation: BAB15098.1. Different initiation.
AK290506 mRNA. Translation: BAF83195.1.
AF228727 Genomic DNA. No translation available.
CH471060 Genomic DNA. Translation: EAW92148.1.
CH471060 Genomic DNA. Translation: EAW92152.1. Sequence problems.
BC015211 mRNA. Translation: AAH15211.1.
BC050655 mRNA. Translation: AAH50655.4.
BC056413 mRNA. Translation: AAH56413.2.
AF151830 mRNA. Translation: AAD34067.1. Different initiation.
AY279109 mRNA. Translation: AAP33690.1. Different initiation.
CCDSiCCDS6367.2. [A8MW92-1]
CCDS6368.1. [A8MW92-2]
RefSeqiNP_057102.4. NM_016018.4. [A8MW92-1]
NP_940915.1. NM_198513.1. [A8MW92-2]
UniGeneiHs.304362.

Genome annotation databases

EnsembliENST00000337920; ENSP00000338269; ENSG00000129292. [A8MW92-2]
ENST00000395386; ENSP00000378784; ENSG00000129292. [A8MW92-1]
ENST00000622263; ENSP00000482945; ENSG00000129292. [A8MW92-1]
GeneIDi51105.
KEGGihsa:51105.
UCSCiuc003ytr.4. human. [A8MW92-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK025268 mRNA. Translation: BAB15098.1. Different initiation.
AK290506 mRNA. Translation: BAF83195.1.
AF228727 Genomic DNA. No translation available.
CH471060 Genomic DNA. Translation: EAW92148.1.
CH471060 Genomic DNA. Translation: EAW92152.1. Sequence problems.
BC015211 mRNA. Translation: AAH15211.1.
BC050655 mRNA. Translation: AAH50655.4.
BC056413 mRNA. Translation: AAH56413.2.
AF151830 mRNA. Translation: AAD34067.1. Different initiation.
AY279109 mRNA. Translation: AAP33690.1. Different initiation.
CCDSiCCDS6367.2. [A8MW92-1]
CCDS6368.1. [A8MW92-2]
RefSeqiNP_057102.4. NM_016018.4. [A8MW92-1]
NP_940915.1. NM_198513.1. [A8MW92-2]
UniGeneiHs.304362.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2EQMNMR-A1-81[»]
2EQUNMR-A85-177[»]
2JTFNMR-A1-74[»]
ProteinModelPortaliA8MW92.
SMRiA8MW92. Positions 3-81, 85-177, 680-727.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi119294. 35 interactions.
IntActiA8MW92. 13 interactions.
MINTiMINT-2830261.
STRINGi9606.ENSP00000378784.

PTM databases

iPTMnetiA8MW92.
PhosphoSiteiA8MW92.

Polymorphism and mutation databases

BioMutaiPHF20L1.

Proteomic databases

EPDiA8MW92.
MaxQBiA8MW92.
PaxDbiA8MW92.
PeptideAtlasiA8MW92.
PRIDEiA8MW92.

Protocols and materials databases

DNASUi51105.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000337920; ENSP00000338269; ENSG00000129292. [A8MW92-2]
ENST00000395386; ENSP00000378784; ENSG00000129292. [A8MW92-1]
ENST00000622263; ENSP00000482945; ENSG00000129292. [A8MW92-1]
GeneIDi51105.
KEGGihsa:51105.
UCSCiuc003ytr.4. human. [A8MW92-1]

Organism-specific databases

CTDi51105.
GeneCardsiPHF20L1.
H-InvDBHIX0007796.
HGNCiHGNC:24280. PHF20L1.
HPAiHPA025060.
HPA028417.
neXtProtiNX_A8MW92.
PharmGKBiPA134874888.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1844. Eukaryota.
ENOG410YHG2. LUCA.
GeneTreeiENSGT00390000006451.
HOVERGENiHBG108227.
InParanoidiA8MW92.
KOiK18402.
OMAiFRNEYPS.
PhylomeDBiA8MW92.
TreeFamiTF106475.

Miscellaneous databases

ChiTaRSiPHF20L1. human.
EvolutionaryTraceiA8MW92.
GenomeRNAii51105.
PROiA8MW92.

Gene expression databases

BgeeiA8MW92.
CleanExiHS_PHF20L1.
ExpressionAtlasiA8MW92. baseline and differential.
GenevisibleiA8MW92. HS.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiIPR014002. Agenet_dom_plant.
IPR022255. DUF3776.
IPR002999. Tudor.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF12618. DUF3776. 1 hit.
[Graphical view]
SMARTiSM00743. Agenet. 2 hits.
SM00333. TUDOR. 2 hits.
[Graphical view]
SUPFAMiSSF57903. SSF57903. 1 hit.
PROSITEiPS01359. ZF_PHD_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 755-1017 (ISOFORM 1).
    Tissue: Brain and Colon.
  2. "DNA sequence and analysis of human chromosome 8."
    Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S., Garber M., Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., Allen N.R., Anderson S., Asakawa T.
    , Blechschmidt K., Bloom T., Borowsky M.L., Butler J., Cook A., Corum B., DeArellano K., DeCaprio D., Dooley K.T., Dorris L. III, Engels R., Gloeckner G., Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K., Jaffe D.B., Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P., Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H., Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C., O'Leary S.B., O'Neill K., Parker S.C.J., Polley A., Raymond C.K., Reichwald K., Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R., Smith C.L., Sneddon T.P., Talamas J.A., Tenzin P., Topham K., Venkataraman V., Wen G., Yamazaki S., Young S.K., Zeng Q., Zimmer A.R., Rosenthal A., Birren B.W., Platzer M., Shimizu N., Lander E.S.
    Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 613-1017 (ISOFORM 1).
    Tissue: Uterus.
  5. "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics."
    Lai C.-H., Chou C.-Y., Ch'ang L.-Y., Liu C.-S., Lin W.-C.
    Genome Res. 10:703-713(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 109-1017 (ISOFORM 4).
  6. "Cloning and characterization of a novel PHD finger gene."
    Shan Y.X., Huang C.Q., Yu L.
    Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 555-1017 (ISOFORM 1).
  7. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
    Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M.
    Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-909, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  8. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
    Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.
    J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-433, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Liver.
  9. "Solution structure of the tudor domain of PHD finger protein 20-like 1."
    RIKEN structural genomics initiative (RSGI)
    Submitted (OCT-2007) to the PDB data bank
    Cited for: STRUCTURE BY NMR OF 1-181 (ISOFORM 2).

Entry informationi

Entry nameiP20L1_HUMAN
AccessioniPrimary (citable) accession number: A8MW92
Secondary accession number(s): A8MZC9
, Q86U89, Q86W43, Q96BT0, Q9H702, Q9HBK3, Q9NYR3, Q9Y381
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: January 11, 2011
Last modified: July 6, 2016
This is version 81 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.