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A8MVG7

- A8MVG7_HUMAN

UniProt

A8MVG7 - A8MVG7_HUMAN

Protein
Submitted name:

Integrin beta-2

Gene

ITGB2

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. receptor activity Source: InterPro

    GO - Biological processi

    1. cell-matrix adhesion Source: InterPro
    2. integrin-mediated signaling pathway Source: InterPro
    3. multicellular organismal development Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Integrin beta-2Imported
    Gene namesi
    Name:ITGB2Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 21

    Organism-specific databases

    HGNCiHGNC:6155. ITGB2.

    Subcellular locationi

    GO - Cellular componenti

    1. integrin complex Source: InterPro

    PTM / Processingi

    Proteomic databases

    PRIDEiA8MVG7.

    Expressioni

    Gene expression databases

    ArrayExpressiA8MVG7.
    BgeeiA8MVG7.

    Structurei

    3D structure databases

    ProteinModelPortaliA8MVG7.
    SMRiA8MVG7. Positions 23-49.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000015314.
    OMAiLSTRIMP.

    Family and domain databases

    InterProiIPR015812. Integrin_bsu.
    IPR015439. Integrin_bsu-2.
    IPR016201. Plexin-like_fold.
    [Graphical view]
    PANTHERiPTHR10082. PTHR10082. 1 hit.
    PTHR10082:SF15. PTHR10082:SF15. 1 hit.
    SMARTiSM00423. PSI. 1 hit.
    [Graphical view]
    SUPFAMiSSF103575. SSF103575. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A8MVG7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLGLRPPLLA LVGLLSLGCV LSQECTKFKV SSCRECIESG PGCTWCQKLG    50
    AALGPPAHAT AASSPRRRSR VAPVCPRTEQ GGQAPGGNYL GQAGFFPSPF 100
    WRFSAPLK 108
    Length:108
    Mass (Da):11,357
    Last modified:December 4, 2007 - v1
    Checksum:i212C30A7D3DB4055
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL773603 Genomic DNA. No translation available.
    AL844907 Genomic DNA. No translation available.
    AL844908 Genomic DNA. No translation available.
    KC877928 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000397846; ENSP00000380944; ENSG00000160255.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL773603 Genomic DNA. No translation available.
    AL844907 Genomic DNA. No translation available.
    AL844908 Genomic DNA. No translation available.
    KC877928 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali A8MVG7.
    SMRi A8MVG7. Positions 23-49.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi A8MVG7.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000397846 ; ENSP00000380944 ; ENSG00000160255 .

    Organism-specific databases

    HGNCi HGNC:6155. ITGB2.
    GenAtlasi Search...

    Phylogenomic databases

    HOGENOMi HOG000015314.
    OMAi LSTRIMP.

    Miscellaneous databases

    ChiTaRSi ITGB2. human.
    NextBioi 35464936.

    Gene expression databases

    ArrayExpressi A8MVG7.
    Bgeei A8MVG7.

    Family and domain databases

    InterProi IPR015812. Integrin_bsu.
    IPR015439. Integrin_bsu-2.
    IPR016201. Plexin-like_fold.
    [Graphical view ]
    PANTHERi PTHR10082. PTHR10082. 1 hit.
    PTHR10082:SF15. PTHR10082:SF15. 1 hit.
    SMARTi SM00423. PSI. 1 hit.
    [Graphical view ]
    SUPFAMi SSF103575. SSF103575. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence of human chromosome 21."
      Chromosome 21 mapping and sequencing consortium
      Hattori M., Fujiyama A., Taylor T.D., Watanabe H., Yada T., Park H.-S., Toyoda A., Ishii K., Totoki Y., Choi D.-K., Groner Y., Soeda E., Ohki M., Takagi T., Sakaki Y., Taudien S., Blechschmidt K., Polley A.
      , Menzel U., Delabar J., Kumpf K., Lehmann R., Patterson D., Reichwald K., Rump A., Schillhabel M., Schudy A., Zimmermann W., Rosenthal A., Kudoh J., Shibuya K., Kawasaki K., Asakawa S., Shintani A., Sasaki T., Nagamine K., Mitsuyama S., Antonarakis S.E., Minoshima S., Shimizu N., Nordsiek G., Hornischer K., Brandt P., Scharfe M., Schoen O., Desario A., Reichelt J., Kauer G., Bloecker H., Ramser J., Beck A., Klages S., Hennig S., Riesselmann L., Dagand E., Wehrmeyer S., Borzym K., Gardiner K., Nizetic D., Francis F., Lehrach H., Reinhardt R., Yaspo M.-L.
      Nature 405:311-319(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiA8MVG7_HUMAN
    AccessioniPrimary (citable) accession number: A8MVG7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 4, 2007
    Last sequence update: December 4, 2007
    Last modified: October 1, 2014
    This is version 42 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3