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A8MVG7

- A8MVG7_HUMAN

UniProt

A8MVG7 - A8MVG7_HUMAN

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Protein
Submitted name: Integrin beta-2
Gene
ITGB2
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. receptor activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. cell-matrix adhesion Source: InterPro
  2. integrin-mediated signaling pathway Source: InterPro
  3. multicellular organismal development Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Integrin beta-2Imported
Gene namesi
Name:ITGB2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 21

Organism-specific databases

HGNCiHGNC:6155. ITGB2.

Subcellular locationi

GO - Cellular componenti

  1. integrin complex Source: InterPro
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiA8MVG7.

Expressioni

Gene expression databases

ArrayExpressiA8MVG7.
BgeeiA8MVG7.

Structurei

3D structure databases

ProteinModelPortaliA8MVG7.
SMRiA8MVG7. Positions 23-49.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000015314.
OMAiLSTRIMP.

Family and domain databases

InterProiIPR015812. Integrin_bsu.
IPR015439. Integrin_bsu-2.
IPR016201. Plexin-like_fold.
[Graphical view]
PANTHERiPTHR10082. PTHR10082. 1 hit.
PTHR10082:SF15. PTHR10082:SF15. 1 hit.
SMARTiSM00423. PSI. 1 hit.
[Graphical view]
SUPFAMiSSF103575. SSF103575. 1 hit.

Sequencei

Sequence statusi: Complete.

A8MVG7-1 [UniParc]FASTAAdd to Basket

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MLGLRPPLLA LVGLLSLGCV LSQECTKFKV SSCRECIESG PGCTWCQKLG    50
AALGPPAHAT AASSPRRRSR VAPVCPRTEQ GGQAPGGNYL GQAGFFPSPF 100
WRFSAPLK 108
Length:108
Mass (Da):11,357
Last modified:December 4, 2007 - v1
Checksum:i212C30A7D3DB4055
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL773603 Genomic DNA. No translation available.
AL844907 Genomic DNA. No translation available.
AL844908 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000397846; ENSP00000380944; ENSG00000160255.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL773603 Genomic DNA. No translation available.
AL844907 Genomic DNA. No translation available.
AL844908 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali A8MVG7.
SMRi A8MVG7. Positions 23-49.
ModBasei Search...

Proteomic databases

PRIDEi A8MVG7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000397846 ; ENSP00000380944 ; ENSG00000160255 .

Organism-specific databases

HGNCi HGNC:6155. ITGB2.
GenAtlasi Search...

Phylogenomic databases

HOGENOMi HOG000015314.
OMAi LSTRIMP.

Miscellaneous databases

ChiTaRSi ITGB2. human.
NextBioi 35464936.

Gene expression databases

ArrayExpressi A8MVG7.
Bgeei A8MVG7.

Family and domain databases

InterProi IPR015812. Integrin_bsu.
IPR015439. Integrin_bsu-2.
IPR016201. Plexin-like_fold.
[Graphical view ]
PANTHERi PTHR10082. PTHR10082. 1 hit.
PTHR10082:SF15. PTHR10082:SF15. 1 hit.
SMARTi SM00423. PSI. 1 hit.
[Graphical view ]
SUPFAMi SSF103575. SSF103575. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence of human chromosome 21."
    Chromosome 21 mapping and sequencing consortium
    Hattori M., Fujiyama A., Taylor T.D., Watanabe H., Yada T., Park H.-S., Toyoda A., Ishii K., Totoki Y., Choi D.-K., Groner Y., Soeda E., Ohki M., Takagi T., Sakaki Y., Taudien S., Blechschmidt K., Polley A.
    , Menzel U., Delabar J., Kumpf K., Lehmann R., Patterson D., Reichwald K., Rump A., Schillhabel M., Schudy A., Zimmermann W., Rosenthal A., Kudoh J., Shibuya K., Kawasaki K., Asakawa S., Shintani A., Sasaki T., Nagamine K., Mitsuyama S., Antonarakis S.E., Minoshima S., Shimizu N., Nordsiek G., Hornischer K., Brandt P., Scharfe M., Schoen O., Desario A., Reichelt J., Kauer G., Bloecker H., Ramser J., Beck A., Klages S., Hennig S., Riesselmann L., Dagand E., Wehrmeyer S., Borzym K., Gardiner K., Nizetic D., Francis F., Lehrach H., Reinhardt R., Yaspo M.-L.
    Nature 405:311-319(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiA8MVG7_HUMAN
AccessioniPrimary (citable) accession number: A8MVG7
Entry historyi
Integrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: July 9, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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