A8MVG7 (A8MVG7_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Integrin beta-2 Ensembl ENSP00000380944

Gene names

Name:

ITGB2 Ensembl ENSP00000380944

Organism

Homo sapiens (Human) [Reference proteome] Ensembl ENSP00000380944

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	108 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000380944

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell-matrix adhesion Inferred from electronic annotation. Source: InterPro integrin-mediated signaling pathway Inferred from electronic annotation. Source: InterPro multicellular organismal development Inferred from electronic annotation. Source: InterPro
Cellular_component	integrin complex Inferred from electronic annotation. Source: InterPro
Molecular_function	receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A8MVG7 [UniParc]. Last modified December 4, 2007. Version 1. Checksum: 212C30A7D3DB4055	FASTA	108	11,357
	10 20 30 40 50 60 MLGLRPPLLA LVGLLSLGCV LSQECTKFKV SSCRECIESG PGCTWCQKLG AALGPPAHAT 70 80 90 100 AASSPRRRSR VAPVCPRTEQ GGQAPGGNYL GQAGFFPSPF WRFSAPLK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence of human chromosome 21." Chromosome 21 mapping and sequencing consortium Hattori M., Fujiyama A., Taylor T.D., Watanabe H., Yada T., Park H.-S., Toyoda A., Ishii K., Totoki Y., Choi D.-K., Groner Y., Soeda E., Ohki M., Takagi T., Sakaki Y., Taudien S., Blechschmidt K., Polley A. , Menzel U., Delabar J., Kumpf K., Lehmann R., Patterson D., Reichwald K., Rump A., Schillhabel M., Schudy A., Zimmermann W., Rosenthal A., Kudoh J., Shibuya K., Kawasaki K., Asakawa S., Shintani A., Sasaki T., Nagamine K., Mitsuyama S., Antonarakis S.E., Minoshima S., Shimizu N., Nordsiek G., Hornischer K., Brandt P., Scharfe M., Schoen O., Desario A., Reichelt J., Kauer G., Bloecker H., Ramser J., Beck A., Klages S., Hennig S., Riesselmann L., Dagand E., Wehrmeyer S., Borzym K., Gardiner K., Nizetic D., Francis F., Lehrach H., Reinhardt R., Yaspo M.-L. Nature 405:311-319(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL773603 Genomic DNA. No translation available. AL844907 Genomic DNA. No translation available. AL844908 Genomic DNA. No translation available.
IPI	IPI00795567.
3D structure databases
ProteinModelPortal	A8MVG7.
SMR	A8MVG7. Positions 22-79.
ModBase	Search...
Protein-protein interaction databases
STRING	A8MVG7.
Proteomic databases
PRIDE	A8MVG7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000397846; ENSP00000380944; ENSG00000160255.
Organism-specific databases
HGNC	HGNC:6155. ITGB2.
GenAtlas	Search...
Phylogenomic databases
HOGENOM	HOG000015314.
Gene expression databases
ArrayExpress	A8MVG7.
Bgee	A8MVG7.
Family and domain databases
InterPro	IPR015812. Integrin_bsu. IPR015439. Integrin_bsu-2. IPR003659. Plexin-like. IPR016201. Plexin-like_fold. [Graphical view]
PANTHER	PTHR10082. PTHR10082. 1 hit. PTHR10082:SF15. PTHR10082:SF15. 1 hit.
SMART	SM00423. PSI. 1 hit. [Graphical view]
SUPFAM	SSF103575. Plexin-like_fold. 1 hit.
ProtoNet	Search...
Other
ChiTaRS	ITGB2. human.
NextBio	35464936.

Entry information

Entry name

A8MVG7_HUMAN

Accession

Primary (citable) accession number: A8MVG7

Entry history

Integrated into UniProtKB/TrEMBL:	December 4, 2007
Last sequence update:	December 4, 2007
Last modified:	May 1, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.