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A8MUV4

- A8MUV4_HUMAN

UniProt

A8MUV4 - A8MUV4_HUMAN

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Protein
Submitted name:

Forkhead box protein P2

Gene
FOXP2
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. sequence-specific DNA binding Source: InterPro
  2. sequence-specific DNA binding transcription factor activity Source: InterPro
Complete GO annotation...

Keywords - Ligandi

DNA-bindingSAAS annotations

Names & Taxonomyi

Protein namesi
Submitted name:
Forkhead box protein P2Imported
Gene namesi
Name:FOXP2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 7

Organism-specific databases

HGNCiHGNC:13875. FOXP2.

PTM / Processingi

Proteomic databases

PRIDEiA8MUV4.

Expressioni

Gene expression databases

ArrayExpressiA8MUV4.
BgeeiA8MUV4.

Structurei

3D structure databases

ProteinModelPortaliA8MUV4.
SMRiA8MUV4. Positions 330-388, 482-563.

Family & Domainsi

Sequence similaritiesi

Contains fork-head DNA-binding domain.SAAS annotations

Phylogenomic databases

HOGENOMiHOG000092089.
HOVERGENiHBG051657.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR001766. TF_fork_head.
IPR018122. TF_fork_head_CS.
IPR011991. WHTH_DNA-bd_dom.
IPR015880. Znf_C2H2-like.
[Graphical view]
PfamiPF00250. Fork_head. 1 hit.
[Graphical view]
PRINTSiPR00053. FORKHEAD.
SMARTiSM00339. FH. 1 hit.
SM00355. ZnF_C2H2. 1 hit.
[Graphical view]
PROSITEiPS00658. FORK_HEAD_2. 1 hit.
PS50039. FORK_HEAD_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8MUV4-1 [UniParc]FASTAAdd to Basket

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MMQESATETI SNSSMNQNGM STLSSQLDAG SRDGRSSGDT SSEVSTVELL    50
HLQQQQALQA ARQLLLQQQT SGLKSPKSSD KQRPLQVPVS VAMMTPQVIT 100
PQQMQQILQQ QVLSPQQLQA LLQQQQAVML QQQQQQQQQQ QQQQQQQQQQ 150
QQQQQQQQQQ QQQQQQQQQQ QHPGKQAKEQ QQQQQQQQLA AQQLVFQQQL 200
LQMQQLQQQQ HLLSLQRQGL ISIPPGQAAL PVQSLPQAGL SPAEIQQLWK 250
EVTGVHSMED NGIKHGGLDL TTNNSSSTTS SNTSKASPPI THHSIVNGQS 300
SVLSARRDSS SHEETGASHT LYGHGVCKWP GCESICEDFG QFLKHLNNEH 350
ALDDRSTAQC RVQMQVVQQL EIQLSKERER LQAMMTHLHM RPSEPKPSPK 400
PLNLVSSVTM SKNMLETSPQ SLPQTPTTPT APVTPITQGP SVITPASVPN 450
VGAIRRRHSD KYNIPMSSEI APNYEFYKNA DVRPPFTYAT LIRQAIMESS 500
DRQLTLNEIY SWFTRTFAYF RRNAATWKNA VRHNLSLHKC FVRVENVKGA 550
VWTVDEVEYQ KRRSQKITGS PTLVKNIPTS LGYGAALNAS LQAALAESSL 600
PLLSNPGLIN NASSGLLQAV HEDLNGSLDH IDSNGNSSPG CSPQPHIHSI 650
HVKEEPVIAE DEDCPMSLVT TANHSPELED DREIEEEPLS EDLE 694
Length:694
Mass (Da):77,238
Last modified:June 26, 2013 - v2
Checksum:i7432707B039E43CE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC003992 Genomic DNA. No translation available.
AC020606 Genomic DNA. No translation available.
AC073626 Genomic DNA. No translation available.
AC074000 Genomic DNA. No translation available.
AC092148 Genomic DNA. No translation available.
AC092606 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000393498; ENSP00000377135; ENSG00000128573.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC003992 Genomic DNA. No translation available.
AC020606 Genomic DNA. No translation available.
AC073626 Genomic DNA. No translation available.
AC074000 Genomic DNA. No translation available.
AC092148 Genomic DNA. No translation available.
AC092606 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali A8MUV4.
SMRi A8MUV4. Positions 330-388, 482-563.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi A8MUV4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000393498 ; ENSP00000377135 ; ENSG00000128573 .

Organism-specific databases

HGNCi HGNC:13875. FOXP2.
GenAtlasi Search...

Phylogenomic databases

HOGENOMi HOG000092089.
HOVERGENi HBG051657.

Miscellaneous databases

ChiTaRSi FOXP2. human.
NextBioi 35464916.

Gene expression databases

ArrayExpressi A8MUV4.
Bgeei A8MUV4.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
InterProi IPR001766. TF_fork_head.
IPR018122. TF_fork_head_CS.
IPR011991. WHTH_DNA-bd_dom.
IPR015880. Znf_C2H2-like.
[Graphical view ]
Pfami PF00250. Fork_head. 1 hit.
[Graphical view ]
PRINTSi PR00053. FORKHEAD.
SMARTi SM00339. FH. 1 hit.
SM00355. ZnF_C2H2. 1 hit.
[Graphical view ]
PROSITEi PS00658. FORK_HEAD_2. 1 hit.
PS50039. FORK_HEAD_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence of human chromosome 7."
    Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L.
    , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
    Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiA8MUV4_HUMAN
AccessioniPrimary (citable) accession number: A8MUV4
Entry historyi
Integrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: June 26, 2013
Last modified: July 9, 2014
This is version 51 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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