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A8MUV4

- A8MUV4_HUMAN

UniProt

A8MUV4 - A8MUV4_HUMAN

Protein
Submitted name:

Forkhead box protein P2

Gene

FOXP2

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 52 (01 Oct 2014)
      Sequence version 2 (26 Jun 2013)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. sequence-specific DNA binding Source: InterPro
    2. sequence-specific DNA binding transcription factor activity Source: InterPro

    Keywords - Ligandi

    DNA-bindingSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Forkhead box protein P2Imported
    Gene namesi
    Name:FOXP2Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 7

    Organism-specific databases

    HGNCiHGNC:13875. FOXP2.

    PTM / Processingi

    Proteomic databases

    PRIDEiA8MUV4.

    Expressioni

    Gene expression databases

    ArrayExpressiA8MUV4.
    BgeeiA8MUV4.

    Structurei

    3D structure databases

    ProteinModelPortaliA8MUV4.
    SMRiA8MUV4. Positions 330-388, 482-563.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains fork-head DNA-binding domain.SAAS annotation

    Phylogenomic databases

    HOGENOMiHOG000092089.
    HOVERGENiHBG051657.

    Family and domain databases

    Gene3Di1.10.10.10. 1 hit.
    InterProiIPR001766. TF_fork_head.
    IPR018122. TF_fork_head_CS.
    IPR011991. WHTH_DNA-bd_dom.
    IPR015880. Znf_C2H2-like.
    [Graphical view]
    PfamiPF00250. Fork_head. 1 hit.
    [Graphical view]
    PRINTSiPR00053. FORKHEAD.
    SMARTiSM00339. FH. 1 hit.
    SM00355. ZnF_C2H2. 1 hit.
    [Graphical view]
    PROSITEiPS00658. FORK_HEAD_2. 1 hit.
    PS50039. FORK_HEAD_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A8MUV4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MMQESATETI SNSSMNQNGM STLSSQLDAG SRDGRSSGDT SSEVSTVELL    50
    HLQQQQALQA ARQLLLQQQT SGLKSPKSSD KQRPLQVPVS VAMMTPQVIT 100
    PQQMQQILQQ QVLSPQQLQA LLQQQQAVML QQQQQQQQQQ QQQQQQQQQQ 150
    QQQQQQQQQQ QQQQQQQQQQ QHPGKQAKEQ QQQQQQQQLA AQQLVFQQQL 200
    LQMQQLQQQQ HLLSLQRQGL ISIPPGQAAL PVQSLPQAGL SPAEIQQLWK 250
    EVTGVHSMED NGIKHGGLDL TTNNSSSTTS SNTSKASPPI THHSIVNGQS 300
    SVLSARRDSS SHEETGASHT LYGHGVCKWP GCESICEDFG QFLKHLNNEH 350
    ALDDRSTAQC RVQMQVVQQL EIQLSKERER LQAMMTHLHM RPSEPKPSPK 400
    PLNLVSSVTM SKNMLETSPQ SLPQTPTTPT APVTPITQGP SVITPASVPN 450
    VGAIRRRHSD KYNIPMSSEI APNYEFYKNA DVRPPFTYAT LIRQAIMESS 500
    DRQLTLNEIY SWFTRTFAYF RRNAATWKNA VRHNLSLHKC FVRVENVKGA 550
    VWTVDEVEYQ KRRSQKITGS PTLVKNIPTS LGYGAALNAS LQAALAESSL 600
    PLLSNPGLIN NASSGLLQAV HEDLNGSLDH IDSNGNSSPG CSPQPHIHSI 650
    HVKEEPVIAE DEDCPMSLVT TANHSPELED DREIEEEPLS EDLE 694
    Length:694
    Mass (Da):77,238
    Last modified:June 26, 2013 - v2
    Checksum:i7432707B039E43CE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC003992 Genomic DNA. No translation available.
    AC020606 Genomic DNA. No translation available.
    AC073626 Genomic DNA. No translation available.
    AC074000 Genomic DNA. No translation available.
    AC092148 Genomic DNA. No translation available.
    AC092606 Genomic DNA. No translation available.
    KF458557 Genomic DNA. No translation available.
    KF458560 Genomic DNA. No translation available.
    KF458565 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000393498; ENSP00000377135; ENSG00000128573.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC003992 Genomic DNA. No translation available.
    AC020606 Genomic DNA. No translation available.
    AC073626 Genomic DNA. No translation available.
    AC074000 Genomic DNA. No translation available.
    AC092148 Genomic DNA. No translation available.
    AC092606 Genomic DNA. No translation available.
    KF458557 Genomic DNA. No translation available.
    KF458560 Genomic DNA. No translation available.
    KF458565 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali A8MUV4.
    SMRi A8MUV4. Positions 330-388, 482-563.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi A8MUV4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000393498 ; ENSP00000377135 ; ENSG00000128573 .

    Organism-specific databases

    HGNCi HGNC:13875. FOXP2.
    GenAtlasi Search...

    Phylogenomic databases

    HOGENOMi HOG000092089.
    HOVERGENi HBG051657.

    Miscellaneous databases

    ChiTaRSi FOXP2. human.
    NextBioi 35464916.

    Gene expression databases

    ArrayExpressi A8MUV4.
    Bgeei A8MUV4.

    Family and domain databases

    Gene3Di 1.10.10.10. 1 hit.
    InterProi IPR001766. TF_fork_head.
    IPR018122. TF_fork_head_CS.
    IPR011991. WHTH_DNA-bd_dom.
    IPR015880. Znf_C2H2-like.
    [Graphical view ]
    Pfami PF00250. Fork_head. 1 hit.
    [Graphical view ]
    PRINTSi PR00053. FORKHEAD.
    SMARTi SM00339. FH. 1 hit.
    SM00355. ZnF_C2H2. 1 hit.
    [Graphical view ]
    PROSITEi PS00658. FORK_HEAD_2. 1 hit.
    PS50039. FORK_HEAD_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence of human chromosome 7."
      Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L.
      , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
      Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiA8MUV4_HUMAN
    AccessioniPrimary (citable) accession number: A8MUV4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 4, 2007
    Last sequence update: June 26, 2013
    Last modified: October 1, 2014
    This is version 52 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3