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Protein

Germ cell-specific gene 1-like protein 2

Gene

GSG1L2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Germ cell-specific gene 1-like protein 2Curated
Short name:
GSG1-like protein 2Curated
Gene namesi
Name:GSG1L2Imported
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

HGNCiHGNC:51826. GSG1L2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 88CytoplasmicCurated
Transmembranei9 – 2921HelicalSequence analysisAdd
BLAST
Topological domaini30 – 12091ExtracellularCuratedAdd
BLAST
Transmembranei121 – 14121HelicalSequence analysisAdd
BLAST
Topological domaini142 – 16019CytoplasmicCuratedAdd
BLAST
Transmembranei161 – 18121HelicalSequence analysisAdd
BLAST
Topological domaini182 – 20423ExtracellularCuratedAdd
BLAST
Transmembranei205 – 22521HelicalSequence analysisAdd
BLAST
Topological domaini226 – 29368CytoplasmicCuratedAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini30 – 293264Germ cell-specific gene 1-like protein 2Sequence analysisPRO_0000343701Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi59 – 591N-linked (GlcNAc...)Sequence analysis
Glycosylationi67 – 671N-linked (GlcNAc...)Sequence analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiA8MUP6.
PRIDEiA8MUP6.

Expressioni

Gene expression databases

BgeeiENSG00000214978.

Organism-specific databases

HPAiHPA059428.

Structurei

3D structure databases

ProteinModelPortaliA8MUP6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GSG1 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IGAK. Eukaryota.
ENOG410ZXFF. LUCA.
GeneTreeiENSGT00390000011933.
HOGENOMiHOG000112826.
HOVERGENiHBG069545.
InParanoidiK7EL98.
OMAiCRSPGFD.
OrthoDBiEOG091G0FIO.
TreeFamiTF331388.

Family and domain databases

InterProiIPR012478. GSG-1.
[Graphical view]
PfamiPF07803. GSG-1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8MUP6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDRAKQQQAL LLLPVCLALT FSLTAVVSSH WCEGTRRVVK PLCQDQPGGQ
60 70 80 90 100
HCIHFKRDNS SNGRMDNNSQ AVLYIWELGD DKFIQRGFHV GLWQSCEESL
110 120 130 140 150
NGEDEKCRSF RSVVPAEEQG VLWLSIGGEV LDIVLILTSA ILLGSRVSCR
160 170 180 190 200
SPGFHWLRVD ALVAIFMVLA GLLGMVAHMM YTTIFQITVN LGPEDWKPQT
210 220 230 240 250
WDYGWSYCLA WGSFALCLAV SVSAMSRFTA ARLEFTEKQQ AQNGSRHSQH
260 270 280 290
SFLEPEASES IWKTGAAPCP AEQAFRNVSG HLPPGAPGKV SIC
Length:293
Mass (Da):32,443
Last modified:October 14, 2015 - v3
Checksum:i5B379C0A0EA62815
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC026591 Genomic DNA. No translation available.
AC027045 Genomic DNA. No translation available.
RefSeqiNP_001297148.1. NM_001310219.1.

Genome annotation databases

EnsembliENST00000399363; ENSP00000465978; ENSG00000214978.
GeneIDi644070.
KEGGihsa:644070.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC026591 Genomic DNA. No translation available.
AC027045 Genomic DNA. No translation available.
RefSeqiNP_001297148.1. NM_001310219.1.

3D structure databases

ProteinModelPortaliA8MUP6.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PaxDbiA8MUP6.
PRIDEiA8MUP6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000399363; ENSP00000465978; ENSG00000214978.
GeneIDi644070.
KEGGihsa:644070.

Organism-specific databases

CTDi644070.
GeneCardsiLOC644070.
HGNCiHGNC:51826. GSG1L2.
HPAiHPA059428.
neXtProtiNX_A8MUP6.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IGAK. Eukaryota.
ENOG410ZXFF. LUCA.
GeneTreeiENSGT00390000011933.
HOGENOMiHOG000112826.
HOVERGENiHBG069545.
InParanoidiK7EL98.
OMAiCRSPGFD.
OrthoDBiEOG091G0FIO.
TreeFamiTF331388.

Miscellaneous databases

GenomeRNAii644070.
PROiA8MUP6.

Gene expression databases

BgeeiENSG00000214978.

Family and domain databases

InterProiIPR012478. GSG-1.
[Graphical view]
PfamiPF07803. GSG-1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGS1L2_HUMAN
AccessioniPrimary (citable) accession number: A8MUP6
Secondary accession number(s): K7EL98
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: October 14, 2015
Last modified: September 7, 2016
This is version 52 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.