A8MUP6 (GSG1M_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Putative germ cell-specific gene 1-like protein 2 Short name=GSG1-like protein 2
Organism	Homo sapiens (Human) [Reference proteome]
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	235 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the GSG1 family.

Ontologies

Keywords
Cellular component	Membrane
Domain	Signal Transmembrane Transmembrane helix
PTM	Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 28	28	Potential
	Chain	29 – 235	207	Putative germ cell-specific gene 1-like protein 2		PRO_0000343701
Regions
	Transmembrane	121 – 141	21	Helical; Potential
	Transmembrane	161 – 181	21	Helical; Potential
	Transmembrane	205 – 225	21	Helical; Potential
Amino acid modifications
	Glycosylation	59	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	A8MUP6 [UniParc]. Last modified July 22, 2008. Version 2. Checksum: CD2A7EB5373F496A	FASTA	235	26,305
	10 20 30 40 50 60 MDRAKQQQAL LLLPVCLALT FSLTAVVSSH WCEGTRRVVK PLCQDQPGGQ HCIHFKRDNS 70 80 90 100 110 120 SNGRMDNNSQ AVLYIWELGD DKFIQRGFHV GLWQSCEESL NGEDEKCRSF RSVVPAEEQG 130 140 150 160 170 180 VLWLSIGGEV LDIVLILTSA ILLGSRVSCR SPGFHWLRVD ALVAIFMVLA GLLGMVAHMM 190 200 210 220 230 YTTIFQITVN LGPEDWKPQT WDYGWSYCLA WGSFALCLAV SVSAMSRFTA ARLEF

References

[1]

"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L. , Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C. Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC026591 Genomic DNA. No translation available. AC027045 Genomic DNA. No translation available.
IPI	IPI00787576.
3D structure databases
ProteinModelPortal	A8MUP6.
ModBase	Search...
Proteomic databases
PRIDE	A8MUP6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
GeneCards	GC17M009647.
neXtProt	NX_A8MUP6.
Phylogenomic databases
eggNOG	NOG78518.
HOGENOM	HOG000112826.
HOVERGEN	HBG069545.
InParanoid	A8MUP6.
OrthoDB	EOG42822J.
Gene expression databases
ArrayExpress	A8MUP6.
Bgee	A8MUP6.
Genevestigator	A8MUP6.
Family and domain databases
InterPro	IPR012478. GSG-1. [Graphical view]
Pfam	PF07803. GSG-1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GSG1M_HUMAN

Accession

Primary (citable) accession number: A8MUP6

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 22, 2008
Last sequence update:	July 22, 2008
Last modified:	April 3, 2013
This is version 28 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.