ID   A8MTU2_HUMAN            Unreviewed;       171 AA.
AC   A8MTU2;
DT   04-DEC-2007, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 3.
DT   27-MAR-2024, entry version 97.
DE   SubName: Full=Forkhead box P2 {ECO:0000313|Ensembl:ENSP00000377133.3};
DE   Flags: Fragment;
GN   Name=FOXP2 {ECO:0000313|Ensembl:ENSP00000377133.3};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000377133.3, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000377133.3, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12853948; DOI=10.1038/nature01782;
RA   Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA   Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K.,
RA   Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A.,
RA   Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H., Sun H.,
RA   Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A.,
RA   Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P.,
RA   Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M.,
RA   Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S.,
RA   Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R.,
RA   Strowmatt C., Latreille P., Miller N., Johnson D., Murray J.,
RA   Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W.,
RA   Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E.,
RA   Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A.,
RA   Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA   Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E.,
RA   Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A.,
RA   Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A.,
RA   Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R.,
RA   McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H.,
RA   Wilson R.K.;
RT   "The DNA sequence of human chromosome 7.";
RL   Nature 424:157-164(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000377133.3}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; AC073626; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC074000; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC092148; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC092606; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF458557; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF458560; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF458565; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A8MTU2; -.
DR   MassIVE; A8MTU2; -.
DR   MaxQB; A8MTU2; -.
DR   PeptideAtlas; A8MTU2; -.
DR   ProteomicsDB; 2052; -.
DR   Antibodypedia; 672; 511 antibodies from 40 providers.
DR   Ensembl; ENST00000393495.7; ENSP00000377133.3; ENSG00000128573.28.
DR   UCSC; uc064hff.1; human.
DR   HGNC; HGNC:13875; FOXP2.
DR   VEuPathDB; HostDB:ENSG00000128573; -.
DR   GeneTree; ENSGT00940000155480; -.
DR   HOGENOM; CLU_1566511_0_0_1; -.
DR   ChiTaRS; FOXP2; human.
DR   Proteomes; UP000005640; Chromosome 7.
DR   Bgee; ENSG00000128573; Expressed in buccal mucosa cell and 180 other cell types or tissues.
DR   ExpressionAtlas; A8MTU2; baseline and differential.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   PANTHER; PTHR45796; FORKHEAD BOX P, ISOFORM C; 1.
DR   PANTHER; PTHR45796:SF1; FORKHEAD BOX PROTEIN P2; 1.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0007829|MaxQB:A8MTU2,
KW   ECO:0007829|PeptideAtlas:A8MTU2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT   REGION          1..44
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          140..171
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        142..166
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         171
FT                   /evidence="ECO:0000313|Ensembl:ENSP00000377133.3"
SQ   SEQUENCE   171 AA;  18494 MW;  2CF3697DE748EAF3 CRC64;
     MMQESATETI SNSSMNQNGM STLSSQLDAG SRDGRSSGDT SSEVSTVELL HLQQQQQQQQ
     QQQLAAQQLV FQQQLLQMQQ LQQQQHLLSL QRQGLISIPP GQAALPVQSL PQAGLSPAEI
     QQLWKEVTGV HSMEDNGIKH GGLDLTTNNS SSTTSSNTSK ASPPITHHSI V
//