Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

A8MTL3 (CN164_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
RING finger protein C14orf164
Gene names
Name:C14orf164
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length300 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 RING-type zinc finger.

Sequence caution

The sequence EB710205 differs from that shown. Reason: Frameshift at position 40.

Ontologies

Keywords
   DomainCoiled coil
Zinc-finger
   LigandMetal-binding
Zinc
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionzinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 300300RING finger protein C14orf164
PRO_0000349181

Regions

Zinc finger6 – 4035RING-type
Coiled coil87 – 12438 Potential

Experimental info

Sequence conflict2271S → T in EB710205. Ref.3
Sequence conflict2341G → E in EB710205. Ref.3

Sequences

Sequence LengthMass (Da)Tools
A8MTL3 [UniParc].

Last modified December 4, 2007. Version 1.
Checksum: A064DB5E3DCE0DFE

FASTA30033,570
        10         20         30         40         50         60 
MDWFHCNQCF RKDGAHFFVT SCGHIFCKKC VTLEKCAVCG TACKHLALSD NLKPQEKMFF 

        70         80         90        100        110        120 
KSPVETALQY FSHISQVWSF QKKQTDLLIA FYKHRITKLE TAMQEAQQAL VSQDKELSVL 

       130        140        150        160        170        180 
RKENGELKKF LAILKESPSR YQGSRSITPR PVGITSPSQS VTPRPSFQHS SQVVSRSSSA 

       190        200        210        220        230        240 
ESIPYREAGF GSLGQGGRGL QGRRTPRDSY NETPSPASTH SLSYRTSSAS SGQGIFSFRP 

       250        260        270        280        290        300 
SPNGHSGHTR VLTPNNFAQR ESTTTLESLP SFQLPVLQTL YQQRRHMGLP SGREAWTTSR 

« Hide

References

[1]"The DNA sequence and analysis of human chromosome 14."
Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C., Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A., Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S., Sun H., Du H. expand/collapse author list , Pepin K., Artiguenave F., Robert C., Cruaud C., Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P., Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N., Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C., Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S., Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B., Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M., Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S., Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D., Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A., Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M., Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V., Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L., Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J., Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W., Quetier F., Waterston R., Hood L., Weissenbach J.
Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]"Exhaustive RT-PCR and sequencing of all novel TWINSCAN predictions in human."
Stevens M., Wei C., Gross S.S., McPherson J., Brent M.R.
Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 34-250.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL117258 Genomic DNA. No translation available.
CH471078 Genomic DNA. Translation: EAW66180.1.
EB710205 mRNA. No translation available.
CCDSCCDS61401.1.
RefSeqNP_001269251.1. NM_001282322.1.

3D structure databases

ProteinModelPortalA8MTL3.
SMRA8MTL3. Positions 4-46.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteA8MTL3.

Proteomic databases

PaxDbA8MTL3.
PRIDEA8MTL3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000399910; ENSP00000382794; ENSG00000215277.
ENST00000430154; ENSP00000397830; ENSG00000215277.
GeneID100507650.
KEGGhsa:100507650.

Organism-specific databases

CTD100507650.
GeneCardsGC14P023657.
HGNCHGNC:20438. C14orf164.
HPAHPA053574.
neXtProtNX_A8MTL3.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG122049.
HOGENOMHOG000155629.
HOVERGENHBG097206.
InParanoidA8MTL3.
OMAYQQRQMG.
OrthoDBEOG776SRM.
PhylomeDBA8MTL3.
TreeFamTF319600.

Gene expression databases

ArrayExpressA8MTL3.
BgeeA8MTL3.
GenevestigatorA8MTL3.

Family and domain databases

InterProIPR001841. Znf_RING.
IPR017907. Znf_RING_CS.
[Graphical view]
PfamPF14634. zf-RING_5. 1 hit.
[Graphical view]
SMARTSM00184. RING. 1 hit.
[Graphical view]
PROSITEPS00518. ZF_RING_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCN164_HUMAN
AccessionPrimary (citable) accession number: A8MTL3
Entry history
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: December 4, 2007
Last modified: July 9, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 14

Human chromosome 14: entries, gene names and cross-references to MIM