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A8MTL3

- R212B_HUMAN

UniProt

A8MTL3 - R212B_HUMAN

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Protein
RING finger protein 212B
Gene
RNF212B, C14orf164
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri6 – 4035RING-type
Add
BLAST

GO - Molecular functioni

  1. zinc ion binding Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
RING finger protein 212B
Gene namesi
Name:RNF212B
Synonyms:C14orf164
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 14

Organism-specific databases

HGNCiHGNC:20438. RNF212B.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 300300RING finger protein 212B
PRO_0000349181Add
BLAST

Proteomic databases

PaxDbiA8MTL3.
PRIDEiA8MTL3.

PTM databases

PhosphoSiteiA8MTL3.

Expressioni

Gene expression databases

ArrayExpressiA8MTL3.
BgeeiA8MTL3.
GenevestigatoriA8MTL3.

Organism-specific databases

HPAiHPA053574.

Structurei

3D structure databases

ProteinModelPortaliA8MTL3.
SMRiA8MTL3. Positions 4-46.

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili87 – 12438 Reviewed prediction
Add
BLAST

Sequence similaritiesi

Keywords - Domaini

Coiled coil, Zinc-finger

Phylogenomic databases

eggNOGiNOG122049.
HOGENOMiHOG000155629.
HOVERGENiHBG097206.
InParanoidiA8MTL3.
OMAiYQQRQMG.
OrthoDBiEOG776SRM.
PhylomeDBiA8MTL3.
TreeFamiTF319600.

Family and domain databases

InterProiIPR001841. Znf_RING.
IPR017907. Znf_RING_CS.
[Graphical view]
PfamiPF14634. zf-RING_5. 1 hit.
[Graphical view]
SMARTiSM00184. RING. 1 hit.
[Graphical view]
PROSITEiPS00518. ZF_RING_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8MTL3-1 [UniParc]FASTAAdd to Basket

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MDWFHCNQCF RKDGAHFFVT SCGHIFCKKC VTLEKCAVCG TACKHLALSD    50
NLKPQEKMFF KSPVETALQY FSHISQVWSF QKKQTDLLIA FYKHRITKLE 100
TAMQEAQQAL VSQDKELSVL RKENGELKKF LAILKESPSR YQGSRSITPR 150
PVGITSPSQS VTPRPSFQHS SQVVSRSSSA ESIPYREAGF GSLGQGGRGL 200
QGRRTPRDSY NETPSPASTH SLSYRTSSAS SGQGIFSFRP SPNGHSGHTR 250
VLTPNNFAQR ESTTTLESLP SFQLPVLQTL YQQRRHMGLP SGREAWTTSR 300
Length:300
Mass (Da):33,570
Last modified:December 4, 2007 - v1
Checksum:iA064DB5E3DCE0DFE
GO

Sequence cautioni

The sequence EB710205 differs from that shown. Reason: Frameshift at position 40.

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti227 – 2271S → T in EB710205. 1 Publication
Sequence conflicti234 – 2341G → E in EB710205. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL117258 Genomic DNA. No translation available.
CH471078 Genomic DNA. Translation: EAW66180.1.
EB710205 mRNA. No translation available.
CCDSiCCDS61401.1.
RefSeqiNP_001269251.1. NM_001282322.1.

Genome annotation databases

EnsembliENST00000399910; ENSP00000382794; ENSG00000215277.
ENST00000430154; ENSP00000397830; ENSG00000215277.
GeneIDi100507650.
KEGGihsa:100507650.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL117258 Genomic DNA. No translation available.
CH471078 Genomic DNA. Translation: EAW66180.1 .
EB710205 mRNA. No translation available.
CCDSi CCDS61401.1.
RefSeqi NP_001269251.1. NM_001282322.1.

3D structure databases

ProteinModelPortali A8MTL3.
SMRi A8MTL3. Positions 4-46.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei A8MTL3.

Proteomic databases

PaxDbi A8MTL3.
PRIDEi A8MTL3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000399910 ; ENSP00000382794 ; ENSG00000215277 .
ENST00000430154 ; ENSP00000397830 ; ENSG00000215277 .
GeneIDi 100507650.
KEGGi hsa:100507650.

Organism-specific databases

CTDi 100507650.
GeneCardsi GC14P023657.
HGNCi HGNC:20438. RNF212B.
HPAi HPA053574.
neXtProti NX_A8MTL3.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG122049.
HOGENOMi HOG000155629.
HOVERGENi HBG097206.
InParanoidi A8MTL3.
OMAi YQQRQMG.
OrthoDBi EOG776SRM.
PhylomeDBi A8MTL3.
TreeFami TF319600.

Gene expression databases

ArrayExpressi A8MTL3.
Bgeei A8MTL3.
Genevestigatori A8MTL3.

Family and domain databases

InterProi IPR001841. Znf_RING.
IPR017907. Znf_RING_CS.
[Graphical view ]
Pfami PF14634. zf-RING_5. 1 hit.
[Graphical view ]
SMARTi SM00184. RING. 1 hit.
[Graphical view ]
PROSITEi PS00518. ZF_RING_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The DNA sequence and analysis of human chromosome 14."
    Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C., Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A., Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S., Sun H., Du H.
    , Pepin K., Artiguenave F., Robert C., Cruaud C., Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P., Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N., Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C., Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S., Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B., Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M., Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S., Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D., Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A., Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M., Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V., Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L., Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J., Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W., Quetier F., Waterston R., Hood L., Weissenbach J.
    Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "Exhaustive RT-PCR and sequencing of all novel TWINSCAN predictions in human."
    Stevens M., Wei C., Gross S.S., McPherson J., Brent M.R.
    Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 34-250.

Entry informationi

Entry nameiR212B_HUMAN
AccessioniPrimary (citable) accession number: A8MTL3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: December 4, 2007
Last modified: September 3, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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