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A8MT82 (CTLFB_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative centaurin-gamma-like family member 11P
Gene names
Name:CTGLF11P
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length671 AA.
Sequence statusComplete.
Protein existenceUncertain

General annotation (Comments)

Function

Putative GTPase-activating protein Potential.

Miscellaneous

Encoded by one of the numerous copies of centaurin gamma-like genes clustered in the q11 region of the chromosome 10.

Sequence similarities

Belongs to the centaurin gamma-like family.

Contains 2 ANK repeats.

Contains 1 Arf-GAP domain.

Contains 1 PH domain.

Caution

Could be the product of a pseudogene.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 671671Putative centaurin-gamma-like family member 11P
PRO_0000348941

Regions

Domain267 – 428162PH
Domain449 – 569121Arf-GAP
Repeat608 – 63730ANK 1
Repeat641 – 67030ANK 2
Zinc finger464 – 48724C4-type

Sequences

Sequence LengthMass (Da)Tools
A8MT82 [UniParc].

Last modified September 2, 2008. Version 2.
Checksum: DFC4E5F84EC3B25F

FASTA67174,058
        10         20         30         40         50         60 
MGNILTCRVH PSVSLEFDQQ QGSVCPSESE IYEAGAKDRM AGAPMAAAVQ PAEVTVEVGE 

        70         80         90        100        110        120 
DLHMHHVRDR EMPEALEFNP SANPEASTIF QRNSQTDVVE IRRSNCTNHV STERFSQQYS 

       130        140        150        160        170        180 
SCSTIFLDDS TASQHYLTMT IISVTLEIPH HITQRDADRS LSIPDEQLTH LRHSSFCSTQ 

       190        200        210        220        230        240 
VSTVHITKNR NGGGSLNNYS SSIPSTPSTS QEDPQFSVPP TANTPTPVCK WSMCWSNLFT 

       250        260        270        280        290        300 
SEKGSHPDKE RKAPENHADT IGSSRAIPIK QGMLLKRSGK WLKTWKKKYV TLCSNGVLTY 

       310        320        330        340        350        360 
YSSLGDYMKN IHKKEIDLRT STIKVPGKWP SLATSACAPI SSSKSNGLSK DMDTGLGDSI 

       370        380        390        400        410        420 
CFSPSISSTT SPKLNLPPSP HANKKKHLKK KSTNNFMIVS ATGQTWHFEA TTYEERDAWV 

       430        440        450        460        470        480 
QAIQSQIVAS LQSCESSKSK SQLTSQSEAM ALQSIQNMRG NAHCVDCETQ NPKWASLNLG 

       490        500        510        520        530        540 
VLMCIECSGI HCSLGTRLSR VRSLELDDWP VELRKVMSSI GNDLANSIWE GSSQGQTKPS 

       550        560        570        580        590        600 
VKSTREEKER WIRSKYEKKL FLAPLPCTEL SLGQHLLRAT ADEDLQTAIL LLAHGSREEV 

       610        620        630        640        650        660 
NETCGEGDGC TALHLACRKG NVVLAQLLIW YRVDVMARDA HGNTALTYAR QASSQECINV 

       670 
LLQYGCPDEC V 

« Hide

References

[1]"The DNA sequence and comparative analysis of human chromosome 10."
Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J. expand/collapse author list , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL603965 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortalA8MT82.
SMRA8MT82. Positions 265-432, 455-649.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEA8MT82.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

GeneCardsGC10P047708.
HGNCHGNC:23660. CTGLF11P.
HPAHPA042490.
neXtProtNX_A8MT82.
GenAtlasSearch...

Phylogenomic databases

HOVERGENHBG054045.
InParanoidA8MT82.

Gene expression databases

GenevestigatorA8MT82.

Family and domain databases

Gene3D1.25.40.20. 1 hit.
2.30.29.30. 2 hits.
InterProIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR001164. ArfGAP.
IPR011993. PH_like_dom.
IPR001849. Pleckstrin_homology.
[Graphical view]
PfamPF12796. Ank_2. 1 hit.
PF01412. ArfGap. 1 hit.
PF00169. PH. 1 hit.
[Graphical view]
PRINTSPR00405. REVINTRACTNG.
SMARTSM00248. ANK. 2 hits.
SM00105. ArfGap. 1 hit.
SM00233. PH. 1 hit.
[Graphical view]
SUPFAMSSF48403. SSF48403. 1 hit.
PROSITEPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 1 hit.
PS50115. ARFGAP. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCTLFB_HUMAN
AccessionPrimary (citable) accession number: A8MT82
Entry history
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: September 2, 2008
Last modified: April 16, 2014
This is version 48 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 10

Human chromosome 10: entries, gene names and cross-references to MIM