SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A8MT82

- CTLFB_HUMAN

UniProt

A8MT82 - CTLFB_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Putative centaurin-gamma-like family member 11P
Gene
CTGLF11P
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Protein uncertaini

Functioni

Putative GTPase-activating protein Reviewed prediction.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri464 – 48724C4-type
Add
BLAST

GO - Molecular functioni

  1. ARF GTPase activator activity Source: InterPro
  2. zinc ion binding Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. regulation of ARF GTPase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GTPase activation

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Putative centaurin-gamma-like family member 11P
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Unplaced

Organism-specific databases

HGNCiHGNC:23660. CTGLF11P.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 671671Putative centaurin-gamma-like family member 11P
PRO_0000348941Add
BLAST

Proteomic databases

PRIDEiA8MT82.

Expressioni

Gene expression databases

GenevestigatoriA8MT82.

Organism-specific databases

HPAiHPA042490.

Structurei

3D structure databases

ProteinModelPortaliA8MT82.
SMRiA8MT82. Positions 265-432, 455-649.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini267 – 428162PH
Add
BLAST
Domaini449 – 569121Arf-GAP
Add
BLAST
Repeati608 – 63730ANK 1
Add
BLAST
Repeati641 – 67030ANK 2
Add
BLAST

Sequence similaritiesi

Contains 2 ANK repeats.
Contains 1 Arf-GAP domain.
Contains 1 PH domain.

Keywords - Domaini

ANK repeat, Repeat, Zinc-finger

Phylogenomic databases

HOVERGENiHBG054045.
InParanoidiA8MT82.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
2.30.29.30. 2 hits.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR001164. ArfGAP.
IPR001849. PH_domain.
IPR011993. PH_like_dom.
[Graphical view]
PfamiPF12796. Ank_2. 1 hit.
PF01412. ArfGap. 1 hit.
PF00169. PH. 1 hit.
[Graphical view]
PRINTSiPR00405. REVINTRACTNG.
SMARTiSM00248. ANK. 2 hits.
SM00105. ArfGap. 1 hit.
SM00233. PH. 1 hit.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 1 hit.
PS50115. ARFGAP. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8MT82-1 [UniParc]FASTAAdd to Basket

« Hide

MGNILTCRVH PSVSLEFDQQ QGSVCPSESE IYEAGAKDRM AGAPMAAAVQ    50
PAEVTVEVGE DLHMHHVRDR EMPEALEFNP SANPEASTIF QRNSQTDVVE 100
IRRSNCTNHV STERFSQQYS SCSTIFLDDS TASQHYLTMT IISVTLEIPH 150
HITQRDADRS LSIPDEQLTH LRHSSFCSTQ VSTVHITKNR NGGGSLNNYS 200
SSIPSTPSTS QEDPQFSVPP TANTPTPVCK WSMCWSNLFT SEKGSHPDKE 250
RKAPENHADT IGSSRAIPIK QGMLLKRSGK WLKTWKKKYV TLCSNGVLTY 300
YSSLGDYMKN IHKKEIDLRT STIKVPGKWP SLATSACAPI SSSKSNGLSK 350
DMDTGLGDSI CFSPSISSTT SPKLNLPPSP HANKKKHLKK KSTNNFMIVS 400
ATGQTWHFEA TTYEERDAWV QAIQSQIVAS LQSCESSKSK SQLTSQSEAM 450
ALQSIQNMRG NAHCVDCETQ NPKWASLNLG VLMCIECSGI HCSLGTRLSR 500
VRSLELDDWP VELRKVMSSI GNDLANSIWE GSSQGQTKPS VKSTREEKER 550
WIRSKYEKKL FLAPLPCTEL SLGQHLLRAT ADEDLQTAIL LLAHGSREEV 600
NETCGEGDGC TALHLACRKG NVVLAQLLIW YRVDVMARDA HGNTALTYAR 650
QASSQECINV LLQYGCPDEC V 671
Length:671
Mass (Da):74,058
Last modified:September 2, 2008 - v2
Checksum:iDFC4E5F84EC3B25F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL603965 Genomic DNA. No translation available.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL603965 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali A8MT82.
SMRi A8MT82. Positions 265-432, 455-649.
ModBasei Search...

Proteomic databases

PRIDEi A8MT82.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

GeneCardsi GC10P047708.
HGNCi HGNC:23660. CTGLF11P.
HPAi HPA042490.
neXtProti NX_A8MT82.
GenAtlasi Search...

Phylogenomic databases

HOVERGENi HBG054045.
InParanoidi A8MT82.

Gene expression databases

Genevestigatori A8MT82.

Family and domain databases

Gene3Di 1.25.40.20. 1 hit.
2.30.29.30. 2 hits.
InterProi IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR001164. ArfGAP.
IPR001849. PH_domain.
IPR011993. PH_like_dom.
[Graphical view ]
Pfami PF12796. Ank_2. 1 hit.
PF01412. ArfGap. 1 hit.
PF00169. PH. 1 hit.
[Graphical view ]
PRINTSi PR00405. REVINTRACTNG.
SMARTi SM00248. ANK. 2 hits.
SM00105. ArfGap. 1 hit.
SM00233. PH. 1 hit.
[Graphical view ]
SUPFAMi SSF48403. SSF48403. 1 hit.
PROSITEi PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 1 hit.
PS50115. ARFGAP. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The DNA sequence and comparative analysis of human chromosome 10."
    Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J.
    , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
    Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiCTLFB_HUMAN
AccessioniPrimary (citable) accession number: A8MT82
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: September 2, 2008
Last modified: September 3, 2014
This is version 49 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Miscellaneous

Encoded by one of the numerous copies of centaurin gamma-like genes clustered in the q11 region of the chromosome 10.

Caution

Could be the product of a pseudogene.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi