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Protein
Submitted name:

Protein S100-B

Gene

S100B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Protein S100-BImported
Submitted name:
S100 calcium binding protein B isoform 2Imported
Gene namesi
Name:S100BImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 21

Organism-specific databases

HGNCiHGNC:10500. S100B.

PTM / Processingi

Proteomic databases

EPDiA8MRB1.
PaxDbiA8MRB1.

Expressioni

Gene expression databases

BgeeiA8MRB1.
ExpressionAtlasiA8MRB1. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000291700.

Structurei

3D structure databases

ProteinModelPortaliA8MRB1.
SMRiA8MRB1. Positions 1-89.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 4643S_100InterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG410IYFX. Eukaryota.
ENOG41127J0. LUCA.
GeneTreeiENSGT00760000119034.
HOGENOMiHOG000246968.
PhylomeDBiA8MRB1.

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
InterProiIPR011992. EF-hand-dom_pair.
IPR028481. S100-B.
IPR013787. S100_Ca-bd_sub.
[Graphical view]
PANTHERiPTHR11639:SF17. PTHR11639:SF17. 1 hit.
PfamiPF01023. S_100. 1 hit.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.

Sequencei

Sequence statusi: Complete.

A8MRB1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSELEKAMVA LIDVFHQYSG REGDKHKLKK SELKELINNE LSHFLERWSL
60 70 80 90
PMLPRLVSNF LCSSYPPALA SQSAGITGNQ RAGGCGQSHG NTGQ
Length:94
Mass (Da):10,343
Last modified:December 4, 2007 - v1
Checksum:iADDC888C374E35C6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP000339 Genomic DNA. No translation available.
KU178320 mRNA. Translation: ALQ33778.1.
UniGeneiHs.422181.

Genome annotation databases

EnsembliENST00000367071; ENSP00000356038; ENSG00000160307.
UCSCiuc002zjv.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP000339 Genomic DNA. No translation available.
KU178320 mRNA. Translation: ALQ33778.1.
UniGeneiHs.422181.

3D structure databases

ProteinModelPortaliA8MRB1.
SMRiA8MRB1. Positions 1-89.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000291700.

Proteomic databases

EPDiA8MRB1.
PaxDbiA8MRB1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000367071; ENSP00000356038; ENSG00000160307.
UCSCiuc002zjv.2. human.

Organism-specific databases

HGNCiHGNC:10500. S100B.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IYFX. Eukaryota.
ENOG41127J0. LUCA.
GeneTreeiENSGT00760000119034.
HOGENOMiHOG000246968.
PhylomeDBiA8MRB1.

Miscellaneous databases

ChiTaRSiS100B. human.
NextBioi35464815.

Gene expression databases

BgeeiA8MRB1.
ExpressionAtlasiA8MRB1. baseline and differential.

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
InterProiIPR011992. EF-hand-dom_pair.
IPR028481. S100-B.
IPR013787. S100_Ca-bd_sub.
[Graphical view]
PANTHERiPTHR11639:SF17. PTHR11639:SF17. 1 hit.
PfamiPF01023. S_100. 1 hit.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence of human chromosome 21."
    Chromosome 21 mapping and sequencing consortium
    Hattori M., Fujiyama A., Taylor T.D., Watanabe H., Yada T., Park H.-S., Toyoda A., Ishii K., Totoki Y., Choi D.-K., Groner Y., Soeda E., Ohki M., Takagi T., Sakaki Y., Taudien S., Blechschmidt K., Polley A.
    , Menzel U., Delabar J., Kumpf K., Lehmann R., Patterson D., Reichwald K., Rump A., Schillhabel M., Schudy A., Zimmermann W., Rosenthal A., Kudoh J., Shibuya K., Kawasaki K., Asakawa S., Shintani A., Sasaki T., Nagamine K., Mitsuyama S., Antonarakis S.E., Minoshima S., Shimizu N., Nordsiek G., Hornischer K., Brandt P., Scharfe M., Schoen O., Desario A., Reichelt J., Kauer G., Bloecker H., Ramser J., Beck A., Klages S., Hennig S., Riesselmann L., Dagand E., Wehrmeyer S., Borzym K., Gardiner K., Nizetic D., Francis F., Lehrach H., Reinhardt R., Yaspo M.-L.
    Nature 405:311-319(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
  3. Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiA8MRB1_HUMAN
AccessioniPrimary (citable) accession number: A8MRB1
Entry historyi
Integrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: March 16, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.