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Protein

Cysteine-rich tail protein 1

Gene

CYSRT1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Cysteine-rich tail protein 1
Gene namesi
Name:CYSRT1
Synonyms:C9orf169
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:30529. CYSRT1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162380848.

Polymorphism and mutation databases

BioMutaiC9orf169.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003322871 – 144Cysteine-rich tail protein 1Add BLAST144

Proteomic databases

MaxQBiA8MQ03.
PaxDbiA8MQ03.
PRIDEiA8MQ03.

PTM databases

iPTMnetiA8MQ03.
PhosphoSitePlusiA8MQ03.

Expressioni

Gene expression databases

CleanExiHS_C9orf169.

Organism-specific databases

HPAiHPA021883.
HPA021886.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
B2R4U64EBI-3867333,EBI-10175477
ADAM12O43184-44EBI-3867333,EBI-12006944
ADAMTSL4Q6UY14-34EBI-3867333,EBI-10173507
APLND3DTF84EBI-3867333,EBI-14157552
B3GNTL1Q2TB724EBI-3867333,EBI-13021467
C22orf39Q6P5X54EBI-3867333,EBI-7317823
CARD10Q9BWT74EBI-3867333,EBI-3866279
CHRNGP07510-24EBI-3867333,EBI-11979451
COL8A1P276584EBI-3867333,EBI-747133
CRCT1Q9UGL94EBI-3867333,EBI-713677
DMRT3Q9NQL94EBI-3867333,EBI-9679045
ERHP840904EBI-3867333,EBI-711389
FZD10Q9ULW24EBI-3867333,EBI-8803802
GUCD1Q96NT3-24EBI-3867333,EBI-11978177
hCG_2008078Q8N4W54EBI-3867333,EBI-11746188
HOXA1P496394EBI-3867333,EBI-740785
HSBP1O755064EBI-3867333,EBI-748664
INO80BQ9C0864EBI-3867333,EBI-715611
INPP5DQ92835-24EBI-3867333,EBI-9092209
IQUBQ8NA544EBI-3867333,EBI-10220600
KCNK1O001804EBI-3867333,EBI-3914675
KPRPQ5T7494EBI-3867333,EBI-10981970
KRT33BQ145254EBI-3867333,EBI-1049638
KRTAP10-11P604124EBI-3867333,EBI-10217483
KRTAP10-7P60409-24EBI-3867333,EBI-10695388
KRTAP10-8P604104EBI-3867333,EBI-10171774
KRTAP12-2P599914EBI-3867333,EBI-10176379
KRTAP2-4Q9BYR94EBI-3867333,EBI-14065470
KRTAP5-6Q6L8G94EBI-3867333,EBI-10250562
KRTAP5-9P263714EBI-3867333,EBI-3958099
KRTAP6-2Q3LI666EBI-3867333,EBI-11962084
KRTAP9-3Q9BYQ34EBI-3867333,EBI-1043191
KRTAP9-8Q9BYQ04EBI-3867333,EBI-11958364
LASP1Q14847-24EBI-3867333,EBI-9088686
LCE1AQ5T7P24EBI-3867333,EBI-11962058
LCE1DQ5T7524EBI-3867333,EBI-11741311
LCE1EQ5T7534EBI-3867333,EBI-11955335
LCE1FQ5T7544EBI-3867333,EBI-11958008
LCE2BO146334EBI-3867333,EBI-11478468
LCE2CQ5TA814EBI-3867333,EBI-11973993
LCE3AQ5TA764EBI-3867333,EBI-9394625
LCE3BQ5TA774EBI-3867333,EBI-11974495
LCE3CQ5T5A84EBI-3867333,EBI-10245291
LCE3DQ9BYE34EBI-3867333,EBI-6658837
LCE3EQ5T5B04EBI-3867333,EBI-10245456
LCE4AQ5TA784EBI-3867333,EBI-10246358
LCE5AQ5TCM94EBI-3867333,EBI-11955689
LGALS9CQ6DKI24EBI-3867333,EBI-9088829
LINC01600Q96MT44EBI-3867333,EBI-12804988
NECTIN2Q92692-24EBI-3867333,EBI-6979889
OTX1P322424EBI-3867333,EBI-740446
P2RX7Q995724EBI-3867333,EBI-1753251
PROCP040704EBI-3867333,EBI-1383018
RAMP3O608964EBI-3867333,EBI-720447
REM2Q8IYK84EBI-3867333,EBI-11304833
RPS19BP1Q86WX34EBI-3867333,EBI-4479407
SEMA4CQ9C0C44EBI-3867333,EBI-10303490
SLC5A5Q929114EBI-3867333,EBI-12313867
SMCPP499014EBI-3867333,EBI-750494
SPATA3A0A024R4B04EBI-3867333,EBI-14123856
SPON1Q9HCB64EBI-3867333,EBI-2431846
SPRY1O436094EBI-3867333,EBI-3866665
TNIP1Q150254EBI-3867333,EBI-357849
TSPAN4O148174EBI-3867333,EBI-8652667
VASNQ6EMK44EBI-3867333,EBI-10249550
WIF1Q9Y5W54EBI-3867333,EBI-3922719
ZMYND10O758004EBI-3867333,EBI-747061
ZNF319Q9P2F94EBI-3867333,EBI-11993110
ZNF581Q9P0T44EBI-3867333,EBI-745520

Protein-protein interaction databases

BioGridi132001. 4 interactors.
IntActiA8MQ03. 538 interactors.
STRINGi9606.ENSP00000351967.

Structurei

3D structure databases

ProteinModelPortaliA8MQ03.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi118 – 141Cys-richAdd BLAST24

Sequence similaritiesi

Belongs to the CYSRT1 family.Curated

Phylogenomic databases

eggNOGiENOG410JEBP. Eukaryota.
ENOG41114BU. LUCA.
HOGENOMiHOG000082660.
HOVERGENiHBG106778.
InParanoidiA8MQ03.
PhylomeDBiA8MQ03.
TreeFamiTF338434.

Family and domain databases

InterProiView protein in InterPro
IPR018904. UPF0574.
PfamiView protein in Pfam
PF10631. DUF2477. 1 hit.

Sequencei

Sequence statusi: Complete.

A8MQ03-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPQEMVVKN PYAHISIPRA HLRPDLGQQL EVASTCSSSS EMQPLPVGPC
60 70 80 90 100
APEPTHLLQP TEVPGPKGAK GNQGAAPIQN QQAWQQPGNP YSSSQRQAGL
110 120 130 140
TYAGPPPAGR GDDIAHHCCC CPCCHCCHCP PFCRCHSCCC CVIS
Length:144
Mass (Da):15,313
Last modified:December 4, 2007 - v1
Checksum:i58C43B5472CA49EF
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti108A → V in AAH52297 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX255925 Genomic DNA. No translation available.
BC052297 mRNA. Translation: AAH52297.1.
RefSeqiNP_945352.3. NM_199001.3.
UniGeneiHs.495540.
Hs.512469.

Genome annotation databases

EnsembliENST00000359069; ENSP00000351967; ENSG00000197191.
GeneIDi375791.
KEGGihsa:375791.

Similar proteinsi

Entry informationi

Entry nameiCRTP1_HUMAN
AccessioniPrimary (citable) accession number: A8MQ03
Secondary accession number(s): Q86UY7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: December 4, 2007
Last modified: August 30, 2017
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries