A8MPQ2 (A8MPQ2_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
cAMP-responsive element modulator Ensembl ENSP00000363866

Gene names

Name:

CREM Ensembl ENSP00000363866

Organism

Homo sapiens (Human) [Reference proteome] Ensembl ENSP00000363866

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	236 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000363866

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	nucleus Inferred from electronic annotation. Source: InterPro
Molecular_function	sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A8MPQ2 [UniParc]. Last modified December 4, 2007. Version 1. Checksum: DCBB6E2218E14D07	FASTA	236	26,269
	10 20 30 40 50 60 MSKCARKKYI KTNPRQMTME TVESQHDGSI TASLTESKSA HVQTQTGQNS IPALAQVAAI 70 80 90 100 110 120 AETDESAESE GVIDSHKRRE ILSRRPSYRK ILNELSSDVP GVPKIEEERS EEEGTPPSIA 130 140 150 160 170 180 TMAVPTSIYQ TSTGQYTATG DMPTYQIRAP TAALPQGVVM AASPGSLHSP QQLAEEATRK 190 200 210 220 230 RELRLMKNRE AARECRRKKK EYVKCLENRV AVLENQNKTL IEELKALKDL YCHKVE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence and comparative analysis of human chromosome 10." Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J. , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J. Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL117336 Genomic DNA. No translation available. AL157783 Genomic DNA. No translation available.
IPI	IPI00877147.
RefSeq	NP_898830.1. NM_183012.1.
UniGene	Hs.200250. Hs.686182.
3D structure databases
ProteinModelPortal	A8MPQ2.
SMR	A8MPQ2. Positions 180-234.
ModBase	Search...
Protein-protein interaction databases
STRING	A8MPQ2.
Protocols and materials databases
DNASU	1390.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000374734; ENSP00000363866; ENSG00000095794.
GeneID	1390.
KEGG	hsa:1390.
UCSC	uc001iye.3. human.
Organism-specific databases
CTD	1390.
HGNC	HGNC:2352. CREM.
PharmGKB	PA26871.
GenAtlas	Search...
Phylogenomic databases
HOGENOM	HOG000007365.
HOVERGEN	HBG011077.
KO	K09052.
Gene expression databases
ArrayExpress	A8MPQ2.
Bgee	A8MPQ2.
Family and domain databases
InterPro	IPR004827. bZIP. IPR003102. Coactivator_CBP_pKID. IPR001630. Leuzip_CREB. [Graphical view]
Pfam	PF00170. bZIP_1. 1 hit. PF02173. pKID. 1 hit. [Graphical view]
PRINTS	PR00041. LEUZIPPRCREB.
SMART	SM00338. BRLZ. 1 hit. [Graphical view]
PROSITE	PS50217. BZIP. 1 hit. PS00036. BZIP_BASIC. 1 hit. PS50953. KID. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	CREM. human.
GenomeRNAi	1390.
NextBio	5649.

Entry information

Entry name

A8MPQ2_HUMAN

Accession

Primary (citable) accession number: A8MPQ2

Entry history

Integrated into UniProtKB/TrEMBL:	December 4, 2007
Last sequence update:	December 4, 2007
Last modified:	May 1, 2013
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.