Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

A8MIB3 (GLSA_ALKOO) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutaminase

EC=3.5.1.2
Gene names
Name:glsA
Ordered Locus Names:Clos_2008
OrganismAlkaliphilus oremlandii (strain OhILAs) (Clostridium oremlandii (strain OhILAs)) [Complete proteome] [HAMAP]
Taxonomic identifier350688 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesClostridiaceaeAlkaliphilus

Protein attributes

Sequence length305 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00313

Sequence similarities

Belongs to the glutaminase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 305305Glutaminase HAMAP-Rule MF_00313
PRO_0000336022

Sites

Binding site611Substrate By similarity
Binding site1131Substrate By similarity
Binding site1581Substrate By similarity
Binding site1651Substrate By similarity
Binding site1891Substrate By similarity
Binding site2411Substrate By similarity
Binding site2591Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
A8MIB3 [UniParc].

Last modified December 4, 2007. Version 1.
Checksum: 97B76E03F436237B

FASTA30533,308
        10         20         30         40         50         60 
MQIELEKILN QNREKIAFGN LPTYIPELTR ANKDALGIYI SQLDGSEFKA GDYDYKFTIQ 

        70         80         90        100        110        120 
SISKVITLIM ALEDWGAEYI FECVGKEPTG DAFNSMMKLE IVRPSKPFNP MINAGAIAVT 

       130        140        150        160        170        180 
SKIKGKSPEE RIQRIMDFFK LVTGNPDLKV NESIYMSEKS TGDRNRAMAY FMKDVGVITG 

       190        200        210        220        230        240 
DVEENLDLYF KQCSIEVTCK DIARIGLFLS SDGVLLETGK QIINPKHSKI AKALMTTCGM 

       250        260        270        280        290        300 
YNASGEFAIN VGIPAKSGVG GGIMAVVPGK MGIGVIGPSL DEKGNSIAGV GVLEQLSKML 


ELSIF 

« Hide

References

[1]"Complete genome of Alkaliphilus oremlandii OhILAs."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Mikhailova N., Stolz J.F., Dawson A., Fisher E., Crable B., Perera E., Lisak J., Ranganathan M., Basu P., Richardson P.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: OhILAs.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000853 Genomic DNA. Translation: ABW19545.1.
RefSeqYP_001513541.1. NC_009922.1.

3D structure databases

ProteinModelPortalA8MIB3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING350688.Clos_2008.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABW19545; ABW19545; Clos_2008.
GeneID5677822.
KEGGaoe:Clos_2008.
PATRIC20869364. VBIAlkOre124042_2108.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2066.
HOGENOMHOG000216890.
KOK01425.
OMARINALML.
OrthoDBEOG6N94BK.
ProtClustDBPRK00971.

Enzyme and pathway databases

BioCycAORE350688:GHBG-2069-MONOMER.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. SSF56601. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLSA_ALKOO
AccessionPrimary (citable) accession number: A8MIB3
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: December 4, 2007
Last modified: February 19, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families