A8MH80 (A8MH80_ALKOO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Guanylate kinase EMBL ABW18967.1
EC=2.7.4.8 EMBL ABW18967.1

Gene names

Ordered Locus Names:

Clos_1423

Organism

Alkaliphilus oremlandii (strain OhILAs) (Clostridium oremlandii (strain OhILAs)) [Complete proteome] [HAMAP] EMBL ABW18967.1

Taxonomic identifier

350688 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Alkaliphilus

Protein attributes

Sequence length	200 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Essential for recycling GMP and indirectly, cGMP By similarity. SAAS SAAS020590
Catalytic activity	ATP + GMP = ADP + GDP. SAAS SAAS020590
Subcellular location	Cytoplasm By similarity SAAS SAAS020590.
Sequence similarities	Contains 1 guanylate kinase-like domain. SAAS SAAS017665

Ontologies

Keywords
Cellular component	Cytoplasm SAAS SAAS020590
Domain	Signal EMBL ABW18967.1
Ligand	ATP-binding SAAS SAAS020590 Nucleotide-binding
Molecular function	Kinase SAAS SAAS020590 EMBL ABW18967.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	purine nucleotide metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW guanylate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 17	17	Potential EMBL ABW18967.1
	Chain	18 – 200	183	Potential EMBL ABW18967.1		PRO_5000281864

Sequences

	Sequence		Length	Mass (Da)
	A8MH80 [UniParc]. Last modified December 4, 2007. Version 1. Checksum: AFAD2162E8D9B656	FASTA	200	22,629
	10 20 30 40 50 60 MSSKGLLIVV SGPSGAGKGT ICKELLNQNP QIKVSISATT RQPRNGEIKG INYFFIDKNK 70 80 90 100 110 120 FELMIKNDDF LEYATVYDNY YGTPKEYVMK NLEDGNDVLL EIDIVGALQI KDRFKDAVFI 130 140 150 160 170 180 FILPPSLEEL KNRIVGRGTE SLADIEKRHG SAISEIEQFI KYDYAVINED VLKAVGDIEA 190 200 IIRAEKCRVL RRTEEIQSKF

References

[1]

"Complete genome of Alkaliphilus oremlandii OhILAs." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Mikhailova N., Stolz J.F., Dawson A., Fisher E., Crable B., Perera E., Lisak J., Ranganathan M., Basu P., Richardson P. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: OhILAs.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000853 Genomic DNA. Translation: ABW18967.1.
RefSeq	YP_001512963.1. NC_009922.1.
3D structure databases
ProteinModelPortal	A8MH80.
ModBase	Search...
Protein-protein interaction databases
STRING	A8MH80.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5676457.
GenomeReviews	Gene locus Clos_1423 in contig CP000853_GR.
KEGG	aoe:Clos_1423.
PATRIC	20868071. VBIAlkOre124042_1492.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG671982.
OMA	DIDWQGT.
ProtClustDB	PRK00300.
Family and domain databases
HAMAP	MF_00328. Guanylate_kinase. [Tree]
InterPro	IPR008144. Guanylate_kin. IPR008145. Guanylate_kin/L-typ_Ca_channel. IPR020590. Guanylate_kinase_CS. IPR017665. Guanylate_kinase_sub. [Graphical view]
KO	K00942.
Pfam	PF00625. Guanylate_kin. 1 hit. [Graphical view]
SMART	SM00072. GuKc. 1 hit. [Graphical view]
TIGRFAMs	TIGR03263. Guanyl_kin. 1 hit.
PROSITE	PS00856. GUANYLATE_KINASE_1. 1 hit. PS50052. GUANYLATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A8MH80_ALKOO

Accession

Primary (citable) accession number: A8MH80

Entry history

Integrated into UniProtKB/TrEMBL:	December 4, 2007
Last sequence update:	December 4, 2007
Last modified:	December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)