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Protein

DNA replication and repair protein RecF

Gene

recF

Organism
Alkaliphilus oremlandii (strain OhILAs) (Clostridium oremlandii (strain OhILAs))
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi30 – 378ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA repair, DNA replication, SOS response

Keywords - Ligandi

ATP-binding, DNA-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciAORE350688:GHBG-4-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA replication and repair protein RecFUniRule annotation
Gene namesi
Name:recFUniRule annotation
Ordered Locus Names:Clos_0004
OrganismiAlkaliphilus oremlandii (strain OhILAs) (Clostridium oremlandii (strain OhILAs))
Taxonomic identifieri350688 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeAlkaliphilus
Proteomesi
  • UP000000269 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 365365DNA replication and repair protein RecFPRO_1000059899Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi350688.Clos_0004.

Structurei

3D structure databases

ProteinModelPortaliA8MEA3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RecF family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C3X. Bacteria.
COG1195. LUCA.
HOGENOMiHOG000269559.
KOiK03629.
OMAiKVQTFIT.
OrthoDBiPOG091H00U7.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
HAMAPiMF_00365. RecF. 1 hit.
InterProiIPR001238. DNA-binding_RecF.
IPR018078. DNA-binding_RecF_CS.
IPR027417. P-loop_NTPase.
IPR003395. RecF/RecN/SMC_N.
[Graphical view]
PANTHERiPTHR32182:SF0. PTHR32182:SF0. 1 hit.
PfamiPF02463. SMC_N. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
TIGRFAMsiTIGR00611. recf. 1 hit.
PROSITEiPS00617. RECF_1. 1 hit.
PS00618. RECF_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8MEA3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIVEELKLIN YRNYEQMNLK FHPRLNVFIG DNAQGKTNLI ESIYLCSAGK
60 70 80 90 100
SFRTNHDQEL INMNKKQAYI HVKVKKVHSD VHIEVRLNSE RKKDLKVNQI
110 120 130 140 150
PLVKMGELLG NLNVVLFSPE DLKLVKEGPS ERRRFMDREI SQISTKFYYT
160 170 180 190 200
LSQYNKILQH RNKLLKYNKG KEIDIEVWDE QLAAAGAWLI VYRRNFIKKI
210 220 230 240 250
SILAKLMHRK ITESIENLEV IYEPNVKVKE NDEVDVIKEK ILQNLKENFN
260 270 280 290 300
VDKQRGLTTC GPHRDDMILK INGLDVKTYG SQGQQRTAVL SLKLAELELV
310 320 330 340 350
KGEVGEYPIL LLDDVMSELD SKRQHYLIHN LKSVQTFITT TMMETLKDLK
360
PEDRAVFYVN KGQID
Length:365
Mass (Da):42,585
Last modified:December 4, 2007 - v1
Checksum:i9C8D6202D7AC39B0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000853 Genomic DNA. Translation: ABW17574.1.
RefSeqiWP_012157889.1. NC_009922.1.

Genome annotation databases

EnsemblBacteriaiABW17574; ABW17574; Clos_0004.
KEGGiaoe:Clos_0004.
PATRICi20865046. VBIAlkOre124042_0004.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000853 Genomic DNA. Translation: ABW17574.1.
RefSeqiWP_012157889.1. NC_009922.1.

3D structure databases

ProteinModelPortaliA8MEA3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi350688.Clos_0004.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABW17574; ABW17574; Clos_0004.
KEGGiaoe:Clos_0004.
PATRICi20865046. VBIAlkOre124042_0004.

Phylogenomic databases

eggNOGiENOG4105C3X. Bacteria.
COG1195. LUCA.
HOGENOMiHOG000269559.
KOiK03629.
OMAiKVQTFIT.
OrthoDBiPOG091H00U7.

Enzyme and pathway databases

BioCyciAORE350688:GHBG-4-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
HAMAPiMF_00365. RecF. 1 hit.
InterProiIPR001238. DNA-binding_RecF.
IPR018078. DNA-binding_RecF_CS.
IPR027417. P-loop_NTPase.
IPR003395. RecF/RecN/SMC_N.
[Graphical view]
PANTHERiPTHR32182:SF0. PTHR32182:SF0. 1 hit.
PfamiPF02463. SMC_N. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
TIGRFAMsiTIGR00611. recf. 1 hit.
PROSITEiPS00617. RECF_1. 1 hit.
PS00618. RECF_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRECF_ALKOO
AccessioniPrimary (citable) accession number: A8MEA3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: December 4, 2007
Last modified: September 7, 2016
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.