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A8MDU6

- DNLI_CALMQ

UniProt

A8MDU6 - DNLI_CALMQ

Protein

DNA ligase

Gene

lig

Organism
Caldivirga maquilingensis (strain ATCC 700844 / DSM 13496 / JCM 10307 / IC-167)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 57 (01 Oct 2014)
      Sequence version 1 (04 Dec 2007)
      Previous versions | rss
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    Functioni

    DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.UniRule annotation

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

    Cofactori

    Divalent metal cations.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei262 – 2621ATPUniRule annotation
    Active sitei264 – 2641N6-AMP-lysine intermediateUniRule annotation
    Binding sitei269 – 2691ATPUniRule annotation
    Binding sitei285 – 2851ATPUniRule annotation
    Binding sitei315 – 3151ATPUniRule annotation
    Binding sitei355 – 3551ATPUniRule annotation
    Binding sitei432 – 4321ATPUniRule annotation
    Binding sitei438 – 4381ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-HAMAP
    4. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. cell cycle Source: UniProtKB-KW
    2. cell division Source: UniProtKB-KW
    3. DNA ligation involved in DNA repair Source: InterPro
    4. DNA recombination Source: UniProtKB-HAMAP
    5. DNA replication Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Ligase

    Keywords - Biological processi

    Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, DNA replication

    Keywords - Ligandi

    ATP-binding, Metal-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciCMAQ397948:GH9M-1148-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Alternative name(s):
    Polydeoxyribonucleotide synthase [ATP]UniRule annotation
    Gene namesi
    Name:ligUniRule annotation
    Ordered Locus Names:Cmaq_1124
    OrganismiCaldivirga maquilingensis (strain ATCC 700844 / DSM 13496 / JCM 10307 / IC-167)
    Taxonomic identifieri397948 [NCBI]
    Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiThermoprotealesThermoproteaceaeCaldivirga
    ProteomesiUP000001137: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 603603DNA ligasePRO_0000365243Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi397948.Cmaq_1124.

    Structurei

    3D structure databases

    ProteinModelPortaliA8MDU6.
    SMRiA8MDU6. Positions 5-595.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATP-dependent DNA ligase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1793.
    HOGENOMiHOG000036008.
    KOiK10747.
    OMAiMVKMLEG.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    HAMAPiMF_00407. DNA_ligase.
    InterProiIPR022865. DNA_ligae_ATP-dep_bac/arc.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A8MDU6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MESDLEFSNI VSVLKLVEAT TQRTVMAKAL SSLLAKTPPQ VIDKVIYFLL    50
    GSLRPDWEGV ELGLAERLTL RAISMATGLP IRQVEELYKK LGDAGEVAKR 100
    AAEIKRSKGG GGTIFDFIDT GPKRRLTISK VYDTLMAIAK ASGEGAQDTK 150
    VKLLSSLLTD AEPDEAKYIT RFVIGRLRLG VADMTILDAL SDAFDVNRDL 200
    LEKAYHVYPD LGKIAKTLAE GGEEAVKAIK VTPGVPIQPM LAERLSSPKE 250
    ILNKLGGVAI CEFKYDGERM QIHKLKDGTV KIFSRRMEDI TNQYPDVAEY 300
    AREAIDAEEF IVEGEGVAID PDTGEFKPFQ ELMHRKRKHN IKEAIEEYPI 350
    NLYLFDVMYV NGQDLTDLPL PDRKKVLFSI IKPHEHVHHA DWIITDDADS 400
    LEKFFLDAIS SGCEGVMCKS VKLGSVYEMG ARGWLWIKYK RDYKSELSDT 450
    MDLVVVGAFW GRGKRAGTYG ALLLAAYDPD SDQFYTVCKV GSGFTDEDLK 500
    KLPQMLEPYK IPHRHPRVVS KMEPDIWFTP GLVLEITGAE ITMSPLHTCC 550
    SVMLKGDVGL AIRFPRFTGR YRTDKRPEDA TTVKEIFEMY SNQKKVKLTD 600
    QVP 603
    Length:603
    Mass (Da):67,561
    Last modified:December 4, 2007 - v1
    Checksum:i616703AB3A417D84
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000852 Genomic DNA. Translation: ABW01952.1.
    RefSeqiWP_012186171.1. NC_009954.1.
    YP_001540942.1. NC_009954.1.

    Genome annotation databases

    EnsemblBacteriaiABW01952; ABW01952; Cmaq_1124.
    GeneIDi5710004.
    KEGGicma:Cmaq_1124.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000852 Genomic DNA. Translation: ABW01952.1 .
    RefSeqi WP_012186171.1. NC_009954.1.
    YP_001540942.1. NC_009954.1.

    3D structure databases

    ProteinModelPortali A8MDU6.
    SMRi A8MDU6. Positions 5-595.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 397948.Cmaq_1124.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABW01952 ; ABW01952 ; Cmaq_1124 .
    GeneIDi 5710004.
    KEGGi cma:Cmaq_1124.

    Phylogenomic databases

    eggNOGi COG1793.
    HOGENOMi HOG000036008.
    KOi K10747.
    OMAi MVKMLEG.

    Enzyme and pathway databases

    BioCyci CMAQ397948:GH9M-1148-MONOMER.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    HAMAPi MF_00407. DNA_ligase.
    InterProi IPR022865. DNA_ligae_ATP-dep_bac/arc.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700844 / DSM 13496 / JCM 10307 / IC-167.

    Entry informationi

    Entry nameiDNLI_CALMQ
    AccessioniPrimary (citable) accession number: A8MDU6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 3, 2009
    Last sequence update: December 4, 2007
    Last modified: October 1, 2014
    This is version 57 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3