Reviewed, UniProtKB/Swiss-Prot A8MCY4 (AROE_CALMQ)

Names and origin

Protein names

Recommended name:
    Shikimate dehydrogenase
    EC=1.1.1.25

Gene names

Name:	aroE
Ordered Locus Names:	Cmaq_0805

Organism

Caldivirga maquilingensis (strain DSMZ 13496 / IC-167) [Complete proteome] [HAMAP]

Taxonomic identifier

397948 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Thermoproteales › Thermoproteaceae › Caldivirga

Protein attributes

Sequence length	269 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Shikimate + NADP+ = 3-dehydroshikimate + NADPH. HAMAP MF_00222
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7. HAMAP MF_00222
Sequence similarities	Belongs to the shikimate dehydrogenase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis
Ligand	NADP
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	binding Inferred from electronic annotation. Source: InterPro shikimate 5-dehydrogenase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 269	269	Shikimate dehydrogenase HAMAP MF_00222		PRO_1000100107
Regions
	Nucleotide binding	122 – 126	5	NADP By similarity
Sites
	Active site	64	1	Proton acceptor Potential

Sequences

	Sequence		Length	Mass (Da)
	A8MCY4-1 [UniParc]. Last modified December 4, 2007. Version 1. Checksum: 6F23FE2A16601CE1	FASTA	269	29,480
	10 20 30 40 50 60 MHVFGLIGYP LNYTLSPQIH NYVFKRLRID AAYVPLRVAS KRLLHFIEFS RDALSGFNVT 70 80 90 100 110 120 IPHKVAVAKL IDELNDDADT IKSVNTVVNS NQKLIGYNTD YVAVEESLIE RGYKGEEALL 130 140 150 160 170 180 IGAGGAARAV VLALSKTGCR AIKVLNRSRE RAVELCGLAN GLGLDCSVVD IGGNYGKPHV 190 200 210 220 230 240 IINATPLSSE EYWLLNLGEL GTMLLLDMAY KPNTETDLIK RARELGIQVI DGVEILVRQA 250 260 LAADKLWLGD FNEPSASEVI KYIKGINPS

References

[1]

"Complete sequence of Caldivirga maquilingensis IC-167." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Ivanova N., Biddle J.F., Zhang Z., Fitz-Gibbon S.T., Lowe T.M., Saltikov C., House C.H., Richardson P. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000852 Genomic DNA. Translation: ABW01640.1.
RefSeq	YP_001540630.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5708718.
GenomeReviews	Gene locus Cmaq_0805 in contig CP000852_GR.
KEGG	cma:Cmaq_0805.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	GELEEIN.
Family and domain databases
HAMAP	MF_00222. [Tree]
InterPro	IPR013708. Shikimate_DH-bd_N. IPR006151. Shikm_DH/Glu-tRNA_Rdtase. [Graphical view]
Pfam	PF01488. Shikimate_DH. 1 hit. PF08501. Shikimate_dh_N. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AROE_CALMQ

Accession

Primary (citable) accession number: A8MCY4

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	December 4, 2007
Last modified:	November 3, 2009
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)